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The map label for this gene is upk

Identifier: 34496782

GI number: 34496782

Start: 1396079

End: 1396891

Strand: Reverse

Name: upk

Synonym: CV_1327

Alternate gene names: 34496782

Gene position: 1396891-1396079 (Counterclockwise)

Preceding gene: 34496783

Following gene: 34496776

Centisome position: 29.4

GC content: 64.82

Gene sequence:

>813_bases
CTGCTGTTCCACTCCCTGATCATGGGCCTGGTCGAGGGCATCACCGAATTCCTCCCGATCTCCTCCACCGGCCACCTGAT
CCTGACCGGCGACCTGCTGGGCTTTCTCGACAAGGAAAAGCGCGACGTCTACGAAATTTTCATCCAGCTGGGCGCAATGC
TGGCGGTGGTGTGGGAGTACCGCCGCAAGATAGGCCATACCGTGGCCGGCGCCGTCCGTCCCGGCGGCGAGCGCAATCTG
CTGCTCGGCATCGTCATCGCCTTCATCCCCGCCGCCGTCGCCGGCCTGCTGTTTTCCAAGCAGATCAAAGCCGTGCTGTT
CAATCCGGTATGCGTGGCCATCGCCTTCATCGTCGGCGGCCTGATCATCCTGTGGGCGGAAAAGCGCGAGCATAAAGTCG
CGGTGGAGACCGTCGACGATCTGAGCCTGAAGGACGCGCTGAAAGTGGGACTGTGCCAGTGCCTGGCCCTGATCCCCGGC
ACCAGCCGCTCCGGCGCCACCATCATCGGCGGCCTGTTCCTGGGCCTGTCGCGCAAGGCGGCCACCGAGTTCTCGTTCTT
TCTCGGCATCCCGACGCTGGGCGCCGCCTCGCTGTACAGCCTCATCAAGCACCGCGACGCGCTGAGCGCGGACGACATCG
GCGTGTTCGCCGTCGGCTTTATCGCGTCCTTCGTCTTCGCCTTCCTCGCCATCCGCGCGCTGCTGCGCTTCATCTCCACG
CACAGCTTCGCGGTGTTCGCCTGGTATCGCATCGCCTTCGGCCTGATCGTGCTGGGGACCTGGTGGAGCGGCCTGGTGAA
CTGGAGCGCCTGA

Upstream 100 bases:

>100_bases
GCGGACGCGCGACAAGCGGCCAACAACATGCATGCTTCTCGCTTATAATCGCGTCCATTCTTCCCAACTCACCCAAACCG
AGCGTTCAATGGATCCGATC

Downstream 100 bases:

>100_bases
AACAGAGGAACCAAAGGCAGGGCAGGCCTATAGGCCTTGCCCTGCCTCAGCCAACAAAAGTTATACCCAGCTGCGAGTGT
GATTGATTGCTTCTTTCCGT

Product: undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLFHSLIMGLVEGITEFLPISSTGHLILTGDLLGFLDKEKRDVYEIFIQLGAMLAVVWEYRRKIGHTVAGAVRPGGERNL
LLGIVIAFIPAAVAGLLFSKQIKAVLFNPVCVAIAFIVGGLIILWAEKREHKVAVETVDDLSLKDALKVGLCQCLALIPG
TSRSGATIIGGLFLGLSRKAATEFSFFLGIPTLGAASLYSLIKHRDALSADDIGVFAVGFIASFVFAFLAIRALLRFIST
HSFAVFAWYRIAFGLIVLGTWWSGLVNWSA

Sequences:

>Translated_270_residues
MLFHSLIMGLVEGITEFLPISSTGHLILTGDLLGFLDKEKRDVYEIFIQLGAMLAVVWEYRRKIGHTVAGAVRPGGERNL
LLGIVIAFIPAAVAGLLFSKQIKAVLFNPVCVAIAFIVGGLIILWAEKREHKVAVETVDDLSLKDALKVGLCQCLALIPG
TSRSGATIIGGLFLGLSRKAATEFSFFLGIPTLGAASLYSLIKHRDALSADDIGVFAVGFIASFVFAFLAIRALLRFIST
HSFAVFAWYRIAFGLIVLGTWWSGLVNWSA
>Mature_270_residues
MLFHSLIMGLVEGITEFLPISSTGHLILTGDLLGFLDKEKRDVYEIFIQLGAMLAVVWEYRRKIGHTVAGAVRPGGERNL
LLGIVIAFIPAAVAGLLFSKQIKAVLFNPVCVAIAFIVGGLIILWAEKREHKVAVETVDDLSLKDALKVGLCQCLALIPG
TSRSGATIIGGLFLGLSRKAATEFSFFLGIPTLGAASLYSLIKHRDALSADDIGVFAVGFIASFVFAFLAIRALLRFIST
HSFAVFAWYRIAFGLIVLGTWWSGLVNWSA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=259, Percent_Identity=46.3320463320463, Blast_Score=194, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_CHRVO (Q7NYE7)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900997.1
- GeneID:   2547669
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1327
- NMPDR:   fig|243365.1.peg.1327
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   Q7NYE7
- BioCyc:   CVIO243365:CV_1327-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29198; Mature: 29198

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc3c1d14)-; HASH(0xed3b77c)-; HASH(0xedd3dd0)-; HASH(0xe6474d0)-; HASH(0xd0b5b0c)-; HASH(0xe72f0f8)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MLFHSLIMGLVEGITEFLPISSTGHLILTGDLLGFLDKEKRDVYEIFIQLGAMLAVVWEY
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
RRKIGHTVAGAVRPGGERNLLLGIVIAFIPAAVAGLLFSKQIKAVLFNPVCVAIAFIVGG
HHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIILWAEKREHKVAVETVDDLSLKDALKVGLCQCLALIPGTSRSGATIIGGLFLGLSRKA
HHEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ATEFSFFLGIPTLGAASLYSLIKHRDALSADDIGVFAVGFIASFVFAFLAIRALLRFIST
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSFAVFAWYRIAFGLIVLGTWWSGLVNWSA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782