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The map label for this gene is pgsA [H]

Identifier: 34496761

GI number: 34496761

Start: 1376752

End: 1377333

Strand: Direct

Name: pgsA [H]

Synonym: CV_1306

Alternate gene names: 34496761

Gene position: 1376752-1377333 (Clockwise)

Preceding gene: 34496760

Following gene: 34496762

Centisome position: 28.98

GC content: 60.48

Gene sequence:

>582_bases
ATGCCCTTCAATTTGCCGATATTACTGACCTGGCTCAGGGTCGCCCTGATCCCGATCTGCGTGGCGGTATTCTTCCTGCC
GGACTCCATTCTGCTGCTGCATAGCCGCAACGCTGTGGGGGCCGGCATTTTCGCATTGGCGGCCGCCACCGACTGGCTGG
ACGGCTACCTGGCGCGCAAGCTGGGGCAGACCTCGGCCTTCGGCGCCTTTCTCGACCCGGTGGCGGACAAGCTGATCGTG
GCCGCGGCGCTGATCCTGCTGGTGCAATTGGGCCGCACCGAGGGTTGGATGGCGATGATCATCATCGGCCGCGAGATCAC
CATTTCGGCGCTGCGCGAATGGATGGCGGGCATGGGCAGCCGCAGCAGCGTCGCCGTCGCCTATATCGGCAAGTTGAAGA
CCGCTGCCCAGATGTTGGCGATCACGCTGCTGCTGTACGACGGCGCGCTTGTCCCGGGCCTGGATGCGCGCGGGTTGGGA
AATTTTTCGATGTACGTTGCTGTCATATTGACTTTGTGGTCAATGATTTATTACCTGCAAATGGCGGCCAAGGAGTTCGC
GGGTAAAAAAATAGACGTTTGA

Upstream 100 bases:

>100_bases
GATCGTTGCATTGATACATGAAAGCGGCGGGTGCCCCTGATCCAGGCTCGGGGCGCCGGCCGGCGTTGTTGACGAGCCTG
AAGCGACAAGACCAAGACCA

Downstream 100 bases:

>100_bases
GGTGTTGACAGAACGAACAAATCTCTATAATTCGCAGTCTCTCGCCGCCGCTGACGAAGCAGCAGCGAGATCAAGCAAAG
CGTTGTAGCAAGTTACGCAG

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MPFNLPILLTWLRVALIPICVAVFFLPDSILLLHSRNAVGAGIFALAAATDWLDGYLARKLGQTSAFGAFLDPVADKLIV
AAALILLVQLGRTEGWMAMIIIGREITISALREWMAGMGSRSSVAVAYIGKLKTAAQMLAITLLLYDGALVPGLDARGLG
NFSMYVAVILTLWSMIYYLQMAAKEFAGKKIDV

Sequences:

>Translated_193_residues
MPFNLPILLTWLRVALIPICVAVFFLPDSILLLHSRNAVGAGIFALAAATDWLDGYLARKLGQTSAFGAFLDPVADKLIV
AAALILLVQLGRTEGWMAMIIIGREITISALREWMAGMGSRSSVAVAYIGKLKTAAQMLAITLLLYDGALVPGLDARGLG
NFSMYVAVILTLWSMIYYLQMAAKEFAGKKIDV
>Mature_192_residues
PFNLPILLTWLRVALIPICVAVFFLPDSILLLHSRNAVGAGIFALAAATDWLDGYLARKLGQTSAFGAFLDPVADKLIVA
AALILLVQLGRTEGWMAMIIIGREITISALREWMAGMGSRSSVAVAYIGKLKTAAQMLAITLLLYDGALVPGLDARGLGN
FSMYVAVILTLWSMIYYLQMAAKEFAGKKIDV

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=186, Percent_Identity=49.4623655913978, Blast_Score=157, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20835; Mature: 20704

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNLPILLTWLRVALIPICVAVFFLPDSILLLHSRNAVGAGIFALAAATDWLDGYLARK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LGQTSAFGAFLDPVADKLIVAAALILLVQLGRTEGWMAMIIIGREITISALREWMAGMGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCC
RSSVAVAYIGKLKTAAQMLAITLLLYDGALVPGLDARGLGNFSMYVAVILTLWSMIYYLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MAAKEFAGKKIDV
HHHHHHCCCCCCC
>Mature Secondary Structure 
PFNLPILLTWLRVALIPICVAVFFLPDSILLLHSRNAVGAGIFALAAATDWLDGYLARK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LGQTSAFGAFLDPVADKLIVAAALILLVQLGRTEGWMAMIIIGREITISALREWMAGMGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCC
RSSVAVAYIGKLKTAAQMLAITLLLYDGALVPGLDARGLGNFSMYVAVILTLWSMIYYLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MAAKEFAGKKIDV
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]