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The map label for this gene is mdtP [H]

Identifier: 34496165

GI number: 34496165

Start: 736207

End: 737646

Strand: Reverse

Name: mdtP [H]

Synonym: CV_0710

Alternate gene names: 34496165

Gene position: 737646-736207 (Counterclockwise)

Preceding gene: 34496169

Following gene: 34496164

Centisome position: 15.53

GC content: 72.29

Gene sequence:

>1440_bases
ATGAGAACCGCATATTTTCGCTGGCGGCCGCTGCCAGCAGCCGGCCTCTCCGCAGCGCTGACGCTGCTGGGAGGCTGCGC
GATGACGCCGGACATGGGGCCGGCGCCGCAGATCAAACCGCTGCAACAATACCAGAATACGCAAAGCCTGCCCGCCTCGG
ACGGCGTCTGGGCCAATGAACAATGGTGGAAAAAATACGGCGACGCGCAACTGAACGCGCTGATGGACGAGGCGCTGAGC
CAGGCGCCCGACCTCGCCGCCGCCCGCGCCCGCGTCGAGCGCGCCGAAGGCCTGGCGCAGCAAGCCGGCGCCGCGCGGCT
GCCCGGCGCGGACCTGAACGCCGCGATCGACCGCGACAAGCAGAGCTACAACAACGGCATGCCGGCGCCGGCTGGCTTCA
ACACCAGCGGCCGCGCCACGCTGGACTTCAGTTACGAACTGGACTTCTGGGGCAAGAACCGCGCCTCGCTGGCCGCCGCG
ACCTCCGACCTGACCGCCGCCCGCGCCGACGCGGCCCAGGCCAGGCTGATGCTGACCGCCTCGCTGGCCGCCGGCTATGC
CGAGCTGGCGCGGCTGTTTTCCGAGCGCGACGCCGCCGCCCAGGCGCTGGAGGTGCGCGCGCACACCGCCAAGCTGATGC
TGCAGCGTTGGCAGCAAGGCATGGACACCCGCGGCGTGCTGCGCCAGGCGGAGTCGCGCGAGGCCGCCGCCCGCGCCGAC
CTGGCCGCCGCCGACGAGAGCATCGCCTTGCAACGCCACAGCCTGGCGGCGCTGATCGGCGCCGGACCAGACCGCGGCCT
GGCCATCGCCCGTCCGGCCGCCGGCTTGTTTCGCGAACAGCGGCTCCCGGCCACGCTGGCAGCCGAATTGCTGGGCCGCC
GACCGGATCTCGCCGCCGCCCGGCTCCGCGCCGAAGCCGCGGCCAAGCGCATCGACGTCGCCCAGGCCCAGTTTTACCCC
AACGTCAACCTCACCGCCTTCGTCGGCGCCCAGTCGCTGGGGTTGGGGCTGTTCGACAAGGCCGGTTCCGGCATAGCCGG
CGTCGGCCCGGCGATCCATCTGCCGATATTCCGCGGCGGCCAGTTGCAAGGCCAGTACCGCGCCGCGCGCGGCGACTACG
ACGCCGCCGTCGCCAGCTACGACGCCACGCTGAGCCAGGCGCTGCGCGAAGTGGCCGACGCCGTCTCCAGCCAGGCCGCG
CTGACGCCGCAACTGCAACAGCGCCAGCAGGCGCTGACGGCCGCCGACGAGGCCTACCGCGTCAGCCGGAACCGCTTCGA
CGGCGGTCTCGCCAATTACCTGGACGTGCTGACCGCCGAAGACAGCGTGATCGCCGCCCGCCGCGGCCTGGCCAGTCTGC
AGGCCCGCCGCTTCTCGCTGGATGTGGCGCTTGTCAAGGCGCTGGGCGGCGGCTACCAGGCAGCCGAACCCGCCCGCTGA

Upstream 100 bases:

>100_bases
CTGAACCGTACGGTTCAATTTTTCTTGACAAGAAATCTCGCTCCGCCATATAACTATACCGTACCGTACAGTTAAATCAA
AACACTCCCGGACAGAGACG

Downstream 100 bases:

>100_bases
GGCCGCCGGCAAACCCATACCAGGACAATCCATCATGAGCGAAAACGCACAAGCCCTGCCGGCCGCCGCGGCGCCCGCCG
CCGCCGGCCGTCCCCTGCAA

Product: outer membrane multidrug resistance lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MRTAYFRWRPLPAAGLSAALTLLGGCAMTPDMGPAPQIKPLQQYQNTQSLPASDGVWANEQWWKKYGDAQLNALMDEALS
QAPDLAAARARVERAEGLAQQAGAARLPGADLNAAIDRDKQSYNNGMPAPAGFNTSGRATLDFSYELDFWGKNRASLAAA
TSDLTAARADAAQARLMLTASLAAGYAELARLFSERDAAAQALEVRAHTAKLMLQRWQQGMDTRGVLRQAESREAAARAD
LAAADESIALQRHSLAALIGAGPDRGLAIARPAAGLFREQRLPATLAAELLGRRPDLAAARLRAEAAAKRIDVAQAQFYP
NVNLTAFVGAQSLGLGLFDKAGSGIAGVGPAIHLPIFRGGQLQGQYRAARGDYDAAVASYDATLSQALREVADAVSSQAA
LTPQLQQRQQALTAADEAYRVSRNRFDGGLANYLDVLTAEDSVIAARRGLASLQARRFSLDVALVKALGGGYQAAEPAR

Sequences:

>Translated_479_residues
MRTAYFRWRPLPAAGLSAALTLLGGCAMTPDMGPAPQIKPLQQYQNTQSLPASDGVWANEQWWKKYGDAQLNALMDEALS
QAPDLAAARARVERAEGLAQQAGAARLPGADLNAAIDRDKQSYNNGMPAPAGFNTSGRATLDFSYELDFWGKNRASLAAA
TSDLTAARADAAQARLMLTASLAAGYAELARLFSERDAAAQALEVRAHTAKLMLQRWQQGMDTRGVLRQAESREAAARAD
LAAADESIALQRHSLAALIGAGPDRGLAIARPAAGLFREQRLPATLAAELLGRRPDLAAARLRAEAAAKRIDVAQAQFYP
NVNLTAFVGAQSLGLGLFDKAGSGIAGVGPAIHLPIFRGGQLQGQYRAARGDYDAAVASYDATLSQALREVADAVSSQAA
LTPQLQQRQQALTAADEAYRVSRNRFDGGLANYLDVLTAEDSVIAARRGLASLQARRFSLDVALVKALGGGYQAAEPAR
>Mature_479_residues
MRTAYFRWRPLPAAGLSAALTLLGGCAMTPDMGPAPQIKPLQQYQNTQSLPASDGVWANEQWWKKYGDAQLNALMDEALS
QAPDLAAARARVERAEGLAQQAGAARLPGADLNAAIDRDKQSYNNGMPAPAGFNTSGRATLDFSYELDFWGKNRASLAAA
TSDLTAARADAAQARLMLTASLAAGYAELARLFSERDAAAQALEVRAHTAKLMLQRWQQGMDTRGVLRQAESREAAARAD
LAAADESIALQRHSLAALIGAGPDRGLAIARPAAGLFREQRLPATLAAELLGRRPDLAAARLRAEAAAKRIDVAQAQFYP
NVNLTAFVGAQSLGLGLFDKAGSGIAGVGPAIHLPIFRGGQLQGQYRAARGDYDAAVASYDATLSQALREVADAVSSQAA
LTPQLQQRQQALTAADEAYRVSRNRFDGGLANYLDVLTAEDSVIAARRGLASLQARRFSLDVALVKALGGGYQAAEPAR

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=469, Percent_Identity=30.7036247334755, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786785, Length=453, Percent_Identity=26.4900662251656, Blast_Score=132, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50721; Mature: 50721

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTAYFRWRPLPAAGLSAALTLLGGCAMTPDMGPAPQIKPLQQYQNTQSLPASDGVWANE
CCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCH
QWWKKYGDAQLNALMDEALSQAPDLAAARARVERAEGLAQQAGAARLPGADLNAAIDRDK
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCH
QSYNNGMPAPAGFNTSGRATLDFSYELDFWGKNRASLAAATSDLTAARADAAQARLMLTA
HHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAAGYAELARLFSERDAAAQALEVRAHTAKLMLQRWQQGMDTRGVLRQAESREAAARAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAAADESIALQRHSLAALIGAGPDRGLAIARPAAGLFREQRLPATLAAELLGRRPDLAAA
HHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHCCCCCHHHH
RLRAEAAAKRIDVAQAQFYPNVNLTAFVGAQSLGLGLFDKAGSGIAGVGPAIHLPIFRGG
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCCCCHHCCCCCCCCCCCEEEECEECCC
QLQGQYRAARGDYDAAVASYDATLSQALREVADAVSSQAALTPQLQQRQQALTAADEAYR
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSRNRFDGGLANYLDVLTAEDSVIAARRGLASLQARRFSLDVALVKALGGGYQAAEPAR
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRTAYFRWRPLPAAGLSAALTLLGGCAMTPDMGPAPQIKPLQQYQNTQSLPASDGVWANE
CCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCH
QWWKKYGDAQLNALMDEALSQAPDLAAARARVERAEGLAQQAGAARLPGADLNAAIDRDK
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCH
QSYNNGMPAPAGFNTSGRATLDFSYELDFWGKNRASLAAATSDLTAARADAAQARLMLTA
HHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAAGYAELARLFSERDAAAQALEVRAHTAKLMLQRWQQGMDTRGVLRQAESREAAARAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAAADESIALQRHSLAALIGAGPDRGLAIARPAAGLFREQRLPATLAAELLGRRPDLAAA
HHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHCCCCCHHHH
RLRAEAAAKRIDVAQAQFYPNVNLTAFVGAQSLGLGLFDKAGSGIAGVGPAIHLPIFRGG
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCCCCHHCCCCCCCCCCCEEEECEECCC
QLQGQYRAARGDYDAAVASYDATLSQALREVADAVSSQAALTPQLQQRQQALTAADEAYR
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSRNRFDGGLANYLDVLTAEDSVIAARRGLASLQARRFSLDVALVKALGGGYQAAEPAR
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]