BacMap

Definition	Chromobacterium violaceum ATCC 12472 chromosome, complete genome.
Accession	NC_005085
Length	4,751,080

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The map label for this gene is bdhA [H]

Identifier: 34496150

GI number: 34496150

Start: 721236

End: 722018

Strand: Reverse

Name: bdhA [H]

Synonym: CV_0695

Alternate gene names: 34496150

Gene position: 722018-721236 (Counterclockwise)

Preceding gene: 34496151

Following gene: 34496149

Centisome position: 15.2

GC content: 65.52

Gene sequence:

>783_bases
ATGCAATTGAACGGAAAAGTCGCCCTGATCACCGGCGCCGCCAGCGGCATCGGCAAGGAAATCGCGCTGGTCTACGCCCG
CGCCGGCGCGGCGGTGGCCATCGCCGACATCAATCTCGACGCCGCGCGCAAAACAGCCGACGAAATCGTCTCCGCCGGCG
GCAAGGCGATAGGCGTGGCGATGGACGTCACCAGCGAGGACGCGGTCAACCAGGGCACCCAGCAAGTGGTGGACGCCTTC
GGCCAGCTGGACATCCTGGTGTCCAACGCCGGCATCCAGATCGTCAATCCCATCGTCAACTACAGCTTCGCCGACTGGAA
GAAGATGCAGGCCATCCACGTGGACGGCGCATTCCTCACCACCAAGGCCGCGCTGCGGCACATGTACCAGGACAAGCGCG
GCGGCGTGGTGATCTACATGGGCTCGGTGCACTCGCACGAGGCCTCAGCTCTGAAATCGGCCTACGTCGCCGCCAAGCAC
GCGCTCTTGGGCCTGGCCCGGGTGCTGGCCAAGGAAGGCGCGCCCTACAATGTGCGCTCGCACGTGATCTGCCCCGGCTT
CGTGCGCACGCCGCTGGTGGACAAGCAGATTCCGGAACAGGCGAAGGAGCTGGGCATCAGCGAGGAGGAAGTGGTCAAGC
GCGTGATGCTGGGCAACACCGTGGACGGCGTGTTCACCACCGTGGACGACGTCGCCCAGACCGCGCTGTTCCTGGCCGCC
TTCCCCAGCGCGGCCCTCACCGGCCAATCCTTCGTCGTCAGCCACGGCTGGTTCATGCAATAA

Upstream 100 bases:

>100_bases
CGTACCGGGTGAGTCTCGATTGCCGGGCGCGCGGTCCCGCGCCGTCCGCCGACACGGTTTTGCCAGTTGTTCATCTTTCA
GAAACGACAGGAGAAGCGCC

Downstream 100 bases:

>100_bases
GGAGCGTCCATGGCGCAGGACAAGCTCGATCCGGCCTGTCATGCCGACGCCGGCCTCCACGGCAGCCCGGCGCTGCCGAA
AGGGCACCGCTACCAGGTGG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MQLNGKVALITGAASGIGKEIALVYARAGAAVAIADINLDAARKTADEIVSAGGKAIGVAMDVTSEDAVNQGTQQVVDAF
GQLDILVSNAGIQIVNPIVNYSFADWKKMQAIHVDGAFLTTKAALRHMYQDKRGGVVIYMGSVHSHEASALKSAYVAAKH
ALLGLARVLAKEGAPYNVRSHVICPGFVRTPLVDKQIPEQAKELGISEEEVVKRVMLGNTVDGVFTTVDDVAQTALFLAA
FPSAALTGQSFVVSHGWFMQ

Sequences:

>Translated_260_residues
MQLNGKVALITGAASGIGKEIALVYARAGAAVAIADINLDAARKTADEIVSAGGKAIGVAMDVTSEDAVNQGTQQVVDAF
GQLDILVSNAGIQIVNPIVNYSFADWKKMQAIHVDGAFLTTKAALRHMYQDKRGGVVIYMGSVHSHEASALKSAYVAAKH
ALLGLARVLAKEGAPYNVRSHVICPGFVRTPLVDKQIPEQAKELGISEEEVVKRVMLGNTVDGVFTTVDDVAQTALFLAA
FPSAALTGQSFVVSHGWFMQ
>Mature_260_residues
MQLNGKVALITGAASGIGKEIALVYARAGAAVAIADINLDAARKTADEIVSAGGKAIGVAMDVTSEDAVNQGTQQVVDAF
GQLDILVSNAGIQIVNPIVNYSFADWKKMQAIHVDGAFLTTKAALRHMYQDKRGGVVIYMGSVHSHEASALKSAYVAAKH
ALLGLARVLAKEGAPYNVRSHVICPGFVRTPLVDKQIPEQAKELGISEEEVVKRVMLGNTVDGVFTTVDDVAQTALFLAA
FPSAALTGQSFVVSHGWFMQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=35.5329949238579, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=30.5555555555556, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=28.9473684210526, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=34.8258706467662, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI66933014, Length=262, Percent_Identity=30.1526717557252, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI10190704, Length=267, Percent_Identity=29.2134831460674, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=34.3023255813954, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI142976729, Length=219, Percent_Identity=28.310502283105, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=30, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI157739938, Length=258, Percent_Identity=25.968992248062, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI210032110, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=30.7291666666667, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=30.7291666666667, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI19923817, Length=193, Percent_Identity=27.4611398963731, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=210, Percent_Identity=27.6190476190476, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=27.7511961722488, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI209862901, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923983, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503301, Length=239, Percent_Identity=25.9414225941423, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI310128830, Length=245, Percent_Identity=26.1224489795918, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI310115468, Length=245, Percent_Identity=26.1224489795918, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4503817, Length=277, Percent_Identity=25.9927797833935, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=26.8041237113402, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=202, Percent_Identity=30.1980198019802, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40254986, Length=138, Percent_Identity=31.1594202898551, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=23.9382239382239, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=29.3193717277487, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=31.9066147859922, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.8185328185328, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=32.295719844358, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=29.7297297297297, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=27.027027027027, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=29.0076335877863, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790717, Length=199, Percent_Identity=29.6482412060301, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=30.2681992337165, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787526, Length=205, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789378, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=29.5454545454545, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367175, Length=198, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=190, Percent_Identity=32.6315789473684, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=36.0406091370558, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=32.2751322751323, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=27.9527559055118, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=27.4131274131274, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=261, Percent_Identity=27.2030651340996, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=29.2490118577075, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=257, Percent_Identity=27.6264591439689, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=29.2307692307692, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=26.7441860465116, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=35.6807511737089, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71982365, Length=140, Percent_Identity=36.4285714285714, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=28.6259541984733, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=27.3408239700375, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=27.5735294117647, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=28.6245353159851, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=28.1481481481481, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.6515151515151, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=25.5208333333333, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=27.9245283018868, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997099, Length=238, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.1375464684015, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=225, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=23.1617647058824, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=33.1578947368421, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=26.9035532994924, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558628, Length=140, Percent_Identity=35, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=26.5917602996255, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=29.6482412060301, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=204, Percent_Identity=25, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=204, Percent_Identity=25, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=31.9148936170213, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324126, Length=263, Percent_Identity=25.0950570342205, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=30.3501945525292, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=36.4102564102564, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=32.319391634981, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17737361, Length=207, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640492, Length=195, Percent_Identity=31.2820512820513, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.3149606299213, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=31.25, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281364892, Length=232, Percent_Identity=28.448275862069, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641232, Length=221, Percent_Identity=27.6018099547511, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=29.6116504854369, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=29.6116504854369, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24649181, Length=225, Percent_Identity=27.1111111111111, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648944, Length=234, Percent_Identity=28.6324786324786, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=29.4685990338164, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357673, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=29.4685990338164, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221510726, Length=198, Percent_Identity=28.2828282828283, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=30.0518134715026, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27405; Mature: 27405

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNGKVALITGAASGIGKEIALVYARAGAAVAIADINLDAARKTADEIVSAGGKAIGVA
CCCCCEEEEEECCCCCCCHHEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEE
MDVTSEDAVNQGTQQVVDAFGQLDILVSNAGIQIVNPIVNYSFADWKKMQAIHVDGAFLT
EECCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEEHHHHCCCCCCHHHEEEEEECCHHHH
TKAALRHMYQDKRGGVVIYMGSVHSHEASALKSAYVAAKHALLGLARVLAKEGAPYNVRS
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HVICPGFVRTPLVDKQIPEQAKELGISEEEVVKRVMLGNTVDGVFTTVDDVAQTALFLAA
CEECCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FPSAALTGQSFVVSHGWFMQ
CCCHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MQLNGKVALITGAASGIGKEIALVYARAGAAVAIADINLDAARKTADEIVSAGGKAIGVA
CCCCCEEEEEECCCCCCCHHEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEE
MDVTSEDAVNQGTQQVVDAFGQLDILVSNAGIQIVNPIVNYSFADWKKMQAIHVDGAFLT
EECCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEEHHHHCCCCCCHHHEEEEEECCHHHH
TKAALRHMYQDKRGGVVIYMGSVHSHEASALKSAYVAAKHALLGLARVLAKEGAPYNVRS
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HVICPGFVRTPLVDKQIPEQAKELGISEEEVVKRVMLGNTVDGVFTTVDDVAQTALFLAA
CEECCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FPSAALTGQSFVVSHGWFMQ
CCCHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]