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The map label for this gene is mlaC [H]

Identifier: 34495901

GI number: 34495901

Start: 463863

End: 464498

Strand: Reverse

Name: mlaC [H]

Synonym: CV_0446

Alternate gene names: 34495901

Gene position: 464498-463863 (Counterclockwise)

Preceding gene: 34495902

Following gene: 34495900

Centisome position: 9.78

GC content: 65.88

Gene sequence:

>636_bases
ATGAAGAAACTGCTTACCCTGTTCTGTCTGATGCTGGGCCTGTCCTCCACCCAGGCGCTGGCCGCCGCCGACAACCCGGT
CGAGCTGATCAAGGACGGCTCGCGCCAGGTGCTGGACGTCCTGAAGCAGGACAACGGCAAAAACACCAAGCAGGTGCGCC
AGCAGGCCGAGGCCATCGCCGTGCCGCTGTTCGACTTCCCGCGCATGACCGCGCTGGCGGTCGGCCTGGGTTGGCGCCAG
GCCACCCCGGAGCAGCGCAATGAGCTGACCCAGCAGTTCCAGACCCTGCTGGTGCGCACCTACTCCACCACCATGACCCG
CTTCAAGACCGCCCAGGTCAGCGTGCAGCCCAATCCGGTGTCCGGCGCCAACGGCAAGGACGTGACCGTGAAGTCCAGCG
TCACCCTTCCGGGCAACGCCAATCCGGTGGCCGTCGACTACGTGCTGAACAAGGGCGACAAGGGCTGGAAGATCTACAAC
GTCAGCGTGGAGGGCGCCAGCCTGGTGACCGTGTACCGCAACAGCTTCAACGAGGAGATCCGCAAGAACGGCGTGGACGG
CCTGATCAAGCTGCTGCAGGACAAGAACGCCGCGCCGGCTCCCGCCGCCGCGTCCGCAGCCAAGGGCAAGGGCTGA

Upstream 100 bases:

>100_bases
GATTTACCGGCAAAGACGCAAGCAAATAGCGTCGCAAGCGGGGCCAACCCTCCTCGCGGCACCGTGTGCCGCCCGACTCG
TGAAAAATGGAATGTCGCAA

Downstream 100 bases:

>100_bases
TGCTGAGCGTCACCTCGCCCGGCGCGGCCAGCCTGTCCGGCCGCATCGACATGGCCAGCTGCGCGTCGCTGGCGCGCCCG
CTGGCCCAGCTGGCCGCCCA

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKKLLTLFCLMLGLSSTQALAAADNPVELIKDGSRQVLDVLKQDNGKNTKQVRQQAEAIAVPLFDFPRMTALAVGLGWRQ
ATPEQRNELTQQFQTLLVRTYSTTMTRFKTAQVSVQPNPVSGANGKDVTVKSSVTLPGNANPVAVDYVLNKGDKGWKIYN
VSVEGASLVTVYRNSFNEEIRKNGVDGLIKLLQDKNAAPAPAAASAAKGKG

Sequences:

>Translated_211_residues
MKKLLTLFCLMLGLSSTQALAAADNPVELIKDGSRQVLDVLKQDNGKNTKQVRQQAEAIAVPLFDFPRMTALAVGLGWRQ
ATPEQRNELTQQFQTLLVRTYSTTMTRFKTAQVSVQPNPVSGANGKDVTVKSSVTLPGNANPVAVDYVLNKGDKGWKIYN
VSVEGASLVTVYRNSFNEEIRKNGVDGLIKLLQDKNAAPAPAAASAAKGKG
>Mature_211_residues
MKKLLTLFCLMLGLSSTQALAAADNPVELIKDGSRQVLDVLKQDNGKNTKQVRQQAEAIAVPLFDFPRMTALAVGLGWRQ
ATPEQRNELTQQFQTLLVRTYSTTMTRFKTAQVSVQPNPVSGANGKDVTVKSSVTLPGNANPVAVDYVLNKGDKGWKIYN
VSVEGASLVTVYRNSFNEEIRKNGVDGLIKLLQDKNAAPAPAAASAAKGKG

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=193, Percent_Identity=23.3160621761658, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 22745; Mature: 22745

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLTLFCLMLGLSSTQALAAADNPVELIKDGSRQVLDVLKQDNGKNTKQVRQQAEAIA
CHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHC
VPLFDFPRMTALAVGLGWRQATPEQRNELTQQFQTLLVRTYSTTMTRFKTAQVSVQPNPV
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
SGANGKDVTVKSSVTLPGNANPVAVDYVLNKGDKGWKIYNVSVEGASLVTVYRNSFNEEI
CCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCEEEEEEEECCCEEEHHHHHHHHHHH
RKNGVDGLIKLLQDKNAAPAPAAASAAKGKG
HHCCHHHHHHHHHCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MKKLLTLFCLMLGLSSTQALAAADNPVELIKDGSRQVLDVLKQDNGKNTKQVRQQAEAIA
CHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHC
VPLFDFPRMTALAVGLGWRQATPEQRNELTQQFQTLLVRTYSTTMTRFKTAQVSVQPNPV
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
SGANGKDVTVKSSVTLPGNANPVAVDYVLNKGDKGWKIYNVSVEGASLVTVYRNSFNEEI
CCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCEEEEEEEECCCEEEHHHHHHHHHHH
RKNGVDGLIKLLQDKNAAPAPAAASAAKGKG
HHCCHHHHHHHHHCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]