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The map label for this gene is bepD [H]

Identifier: 34495890

GI number: 34495890

Start: 455034

End: 456221

Strand: Reverse

Name: bepD [H]

Synonym: CV_0435

Alternate gene names: 34495890

Gene position: 456221-455034 (Counterclockwise)

Preceding gene: 34495897

Following gene: 34495889

Centisome position: 9.6

GC content: 69.78

Gene sequence:

>1188_bases
ATGCAAGCAAGTGCAGTTTTCCCGCGCGCCGCGCGCGGGCTGATGCTGGGCGTAGTGGCCGCCAGCCTGGCGGCCTGCGG
CCAGAAACCCGACGCCCACGCCGGCGGCGCGATGCCGCCGGTGCCGGTGGCCGTGATCAAGGTTCAGCCGGCCGACGTGC
CGGTGTCGTATGAATTCGTCGGCCAGGCGGCCGGCTCGCGCGAGGTGGAAGTGCGCGCCCGCGTCGGCGGCATCCTGCAG
AAGCGTGCCTACGCCGAAGGCAAGCCGGTGAAGGCCGGCGACCTGCTGTTCCAGATCGACCCGGAACCGTTCAAGGCGGC
GCTGGACCAGGCCCGCGCCAACCTGCAGGTGCAGCAGGCGCAGCTGTCGCGCACCAAGCAGGACTACGAGCGCATCATGC
CGCTGTTCAAGGAAAACGCGGTCAGCCAGAAGGACCGCGACGACGCCGTGGCCGCCTACAACGCCGCCAAGGCCTCCACC
GCCGCCGCGCAGGCGCAGGTGGAACAGGCGCAGATCAACCTGGGCTACACCCGCGTCACCGCGCCGATCTCCGGCATCAC
CAGCCAGGAGGCGCGCTCCGAGGGCAGCCTGGTGGCCACCAGCGCCGACGCCAGCCTGCTGACCAAGATCTCGCAGCTGG
ACCCGATCTACGTCAACTTCAGCATGTCCGACAGCGACATGCTGAACCTGCGCAAGATGCAGCACGCCGGCAAGCTGAAG
CTGGCCAACGGCGGCGGTTTCGAAGTCCAGCTCAAGCTGCCGGACGGCAGCATGTACGGCAAGTCCGGCCACCTGAACTT
CACCGACAGCCTGGTGGACACCACCACCGGCACCATCCGCTCGCGCGCCACCTTCGCCAACCCGCAAGGCGGCATCCTGC
CCGGCCAGTTCGTCCGCGTGCAGCTGAACGGCGCGGTGCGCACCGCGGCCATCACCGTGCCGCAGCGCGCGGTGCTGACC
ACGCAGCAGGGCAAGATGGTGTGGGTCGTCAGCGCCGAAGGCAAGGCCGCGCCGCGCCCCATCGTCACCTCGCAGGAAGT
GGGCATGGACGTGCTGGTCGAGCAGGGCCTGAAGGCCGGCGACCAGGTCGTCGTCGACAACATCATCAAGCTGCGTCCGG
GCGCCGAGGTCAAGCCTCACCCGTTCCAGGCCGACGCCAGCGCGCCGGCCGCCGCGGCCAAGCCGTGA

Upstream 100 bases:

>100_bases
GTAAAATGCGCAGACTCGGGGATATGACAATCCAGACCATTCCCCCAATAACAGTAAACCCCTATTACCTTCCGGATTCA
GCTTTCGAGGACTCGAAACC

Downstream 100 bases:

>100_bases
TCCCAGGGGGAACCTGATACATGTTTTCCGCTTTTTTCATCCGGCGACCGATCTTCGCCAGCGTGATCTCCATCGTGATC
ATGCTGGCGGGCCTGGCCGC

Product: multidrug efflux membrane permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQASAVFPRAARGLMLGVVAASLAACGQKPDAHAGGAMPPVPVAVIKVQPADVPVSYEFVGQAAGSREVEVRARVGGILQ
KRAYAEGKPVKAGDLLFQIDPEPFKAALDQARANLQVQQAQLSRTKQDYERIMPLFKENAVSQKDRDDAVAAYNAAKAST
AAAQAQVEQAQINLGYTRVTAPISGITSQEARSEGSLVATSADASLLTKISQLDPIYVNFSMSDSDMLNLRKMQHAGKLK
LANGGGFEVQLKLPDGSMYGKSGHLNFTDSLVDTTTGTIRSRATFANPQGGILPGQFVRVQLNGAVRTAAITVPQRAVLT
TQQGKMVWVVSAEGKAAPRPIVTSQEVGMDVLVEQGLKAGDQVVVDNIIKLRPGAEVKPHPFQADASAPAAAAKP

Sequences:

>Translated_395_residues
MQASAVFPRAARGLMLGVVAASLAACGQKPDAHAGGAMPPVPVAVIKVQPADVPVSYEFVGQAAGSREVEVRARVGGILQ
KRAYAEGKPVKAGDLLFQIDPEPFKAALDQARANLQVQQAQLSRTKQDYERIMPLFKENAVSQKDRDDAVAAYNAAKAST
AAAQAQVEQAQINLGYTRVTAPISGITSQEARSEGSLVATSADASLLTKISQLDPIYVNFSMSDSDMLNLRKMQHAGKLK
LANGGGFEVQLKLPDGSMYGKSGHLNFTDSLVDTTTGTIRSRATFANPQGGILPGQFVRVQLNGAVRTAAITVPQRAVLT
TQQGKMVWVVSAEGKAAPRPIVTSQEVGMDVLVEQGLKAGDQVVVDNIIKLRPGAEVKPHPFQADASAPAAAAKP
>Mature_395_residues
MQASAVFPRAARGLMLGVVAASLAACGQKPDAHAGGAMPPVPVAVIKVQPADVPVSYEFVGQAAGSREVEVRARVGGILQ
KRAYAEGKPVKAGDLLFQIDPEPFKAALDQARANLQVQQAQLSRTKQDYERIMPLFKENAVSQKDRDDAVAAYNAAKAST
AAAQAQVEQAQINLGYTRVTAPISGITSQEARSEGSLVATSADASLLTKISQLDPIYVNFSMSDSDMLNLRKMQHAGKLK
LANGGGFEVQLKLPDGSMYGKSGHLNFTDSLVDTTTGTIRSRATFANPQGGILPGQFVRVQLNGAVRTAAITVPQRAVLT
TQQGKMVWVVSAEGKAAPRPIVTSQEVGMDVLVEQGLKAGDQVVVDNIIKLRPGAEVKPHPFQADASAPAAAAKP

Specific function: Involved in resistance to several unrelated toxic compounds, such as dyes, detergents and antibiotics [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=372, Percent_Identity=40.0537634408602, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789665, Length=362, Percent_Identity=38.6740331491713, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI1789929, Length=364, Percent_Identity=36.8131868131868, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI87082036, Length=343, Percent_Identity=31.7784256559767, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI87081796, Length=356, Percent_Identity=26.9662921348315, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081951, Length=139, Percent_Identity=31.6546762589928, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41586; Mature: 41586

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASAVFPRAARGLMLGVVAASLAACGQKPDAHAGGAMPPVPVAVIKVQPADVPVSYEFV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCEEHHHH
GQAAGSREVEVRARVGGILQKRAYAEGKPVKAGDLLFQIDPEPFKAALDQARANLQVQQA
HCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHH
QLSRTKQDYERIMPLFKENAVSQKDRDDAVAAYNAAKASTAAAQAQVEQAQINLGYTRVT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHEECCEEEEE
APISGITSQEARSEGSLVATSADASLLTKISQLDPIYVNFSMSDSDMLNLRKMQHAGKLK
CCCCCCCCHHHCCCCCEEEECCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEE
LANGGGFEVQLKLPDGSMYGKSGHLNFTDSLVDTTTGTIRSRATFANPQGGILPGQFVRV
EECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEE
QLNGAVRTAAITVPQRAVLTTQQGKMVWVVSAEGKAAPRPIVTSQEVGMDVLVEQGLKAG
EECCCEEEEEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCCHHCCHHHHHHHCCCCC
DQVVVDNIIKLRPGAEVKPHPFQADASAPAAAAKP
CCEEECHHHEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQASAVFPRAARGLMLGVVAASLAACGQKPDAHAGGAMPPVPVAVIKVQPADVPVSYEFV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCEEHHHH
GQAAGSREVEVRARVGGILQKRAYAEGKPVKAGDLLFQIDPEPFKAALDQARANLQVQQA
HCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHH
QLSRTKQDYERIMPLFKENAVSQKDRDDAVAAYNAAKASTAAAQAQVEQAQINLGYTRVT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHEECCEEEEE
APISGITSQEARSEGSLVATSADASLLTKISQLDPIYVNFSMSDSDMLNLRKMQHAGKLK
CCCCCCCCHHHCCCCCEEEECCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEE
LANGGGFEVQLKLPDGSMYGKSGHLNFTDSLVDTTTGTIRSRATFANPQGGILPGQFVRV
EECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEE
QLNGAVRTAAITVPQRAVLTTQQGKMVWVVSAEGKAAPRPIVTSQEVGMDVLVEQGLKAG
EECCCEEEEEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCCHHCCHHHHHHHCCCCC
DQVVVDNIIKLRPGAEVKPHPFQADASAPAAAAKP
CCEEECHHHEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]