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The map label for this gene is dinP [H]

Identifier: 161594047

GI number: 161594047

Start: 4706267

End: 4707406

Strand: Reverse

Name: dinP [H]

Synonym: CV_4363

Alternate gene names: 161594047

Gene position: 4707406-4706267 (Counterclockwise)

Preceding gene: 34499819

Following gene: 34499811

Centisome position: 99.08

GC content: 71.14

Gene sequence:

>1140_bases
ATGAACGCCCCGCAACGCAAGATCATCCACGTCGATTGCGACTGCTTCTACGCCGCGATCGAAATGCGCGACGACCCCAG
CCTGCGCGACGTGCCGCTGGCGGTGGGCGGCCGCCCGGAGACGCGCGGCGTGGTCGCCACCTGCAACTACATCGCGCGGC
GCTACGGCGTGCATTCGGCGATGTCGTCGGCGCGCGCGCTCAGGCTGTGCCCGGAACTATTGATCGTGCCGCCGGACATG
GCGCGCTACCGGCTGGCCAGCCAGCAGATCATGGCCATCTACCAGCGCTACACCGAGGTGATCGAGCCCTTGTCGCTGGA
CGAGGCTTATCTCGACGTCACCGGCCAGCCGCATGAGCGGGGCAGCGCCACGCTGATGGCCGAGGCGATACGCCGCCAGA
TCCGCGACGAGGTGGGCATCACCGCGTCGGCCGGCATCGCGCCCAACAAGTTCCTGGCCAAGGTGGCCAGCGACTGGAAC
AAGCCGGACGGCCAGTATCTGATCCGCCCGCGCGACATCGACGCCTTCGTCGCCGTGTTGCCGGTGGAGAAGATACACGG
CGTCGGCCGCGTCACCGCCGAGCGGCTCCACCGGCTGGGCATACGCAGCTGCGGCGATCTCAGGCGCTGGTCGCCGGCCG
ACCTGTTCCGCCATTTCGGCAGCTTCGGCGAGCGCCTGCTGGCATTGGCGCACGGACGCGACGAGCGGCCGGTGTCCACC
GACCGCAGCCGCAAGACGATCAGCGTCGAGGAGACTTACGCGCAGGACCTGCCCGACCTCGCCAGCTGCCTGTCCAAGCT
GCCGGAGCTGGTGGACCGGCTGCAGGCGCGGCTGGCGCGCAGCGGCAGCCCGGCATTCAAGGGCTTGTCGGTGAAGCTGA
AGTTCGACGATTTCAGCCAGACCACGGTCGAGCAGCCGGGCTACGCGCTGTCGATGGCGGCCTTCGGCCAGCTGCTGCGC
GCCGGCCACGCGCGCGGCGCGCGGCCGGCGCGGCTGCTGGGCGTGGGCGTGAAGCTGGCCGACGATTTCGATCTGCCGCG
CCAGCTGCGGCTGTTTGGCCGCGACGGCCGGCCGCTGCCGGACAGCGCGCCGCCCGCCGAGGCGCCGCCGGGCGGGCCGG
AGGCCGACTCGGCGGCCTAG

Upstream 100 bases:

>100_bases
AAGACGGCTTTCCCGAGCTGAAAATCCTCAAGCAGCGGCTGCGCGACCGCATCGCGCCGGACAAGGCGCTGGGGCACAGC
GACCGTCCCTGAGCGCCGCG

Downstream 100 bases:

>100_bases
CGCTCAGGGCGTCGGCTGGCCCGCGGCCGGCTTGGCGGCGAAGTCGCCGGCGTAGGCCTGGGTCAGCAGCTCCGGCTTCA
GATACTTGCGCAAGGCGGCG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNAPQRKIIHVDCDCFYAAIEMRDDPSLRDVPLAVGGRPETRGVVATCNYIARRYGVHSAMSSARALRLCPELLIVPPDM
ARYRLASQQIMAIYQRYTEVIEPLSLDEAYLDVTGQPHERGSATLMAEAIRRQIRDEVGITASAGIAPNKFLAKVASDWN
KPDGQYLIRPRDIDAFVAVLPVEKIHGVGRVTAERLHRLGIRSCGDLRRWSPADLFRHFGSFGERLLALAHGRDERPVST
DRSRKTISVEETYAQDLPDLASCLSKLPELVDRLQARLARSGSPAFKGLSVKLKFDDFSQTTVEQPGYALSMAAFGQLLR
AGHARGARPARLLGVGVKLADDFDLPRQLRLFGRDGRPLPDSAPPAEAPPGGPEADSAA

Sequences:

>Translated_379_residues
MNAPQRKIIHVDCDCFYAAIEMRDDPSLRDVPLAVGGRPETRGVVATCNYIARRYGVHSAMSSARALRLCPELLIVPPDM
ARYRLASQQIMAIYQRYTEVIEPLSLDEAYLDVTGQPHERGSATLMAEAIRRQIRDEVGITASAGIAPNKFLAKVASDWN
KPDGQYLIRPRDIDAFVAVLPVEKIHGVGRVTAERLHRLGIRSCGDLRRWSPADLFRHFGSFGERLLALAHGRDERPVST
DRSRKTISVEETYAQDLPDLASCLSKLPELVDRLQARLARSGSPAFKGLSVKLKFDDFSQTTVEQPGYALSMAAFGQLLR
AGHARGARPARLLGVGVKLADDFDLPRQLRLFGRDGRPLPDSAPPAEAPPGGPEADSAA
>Mature_379_residues
MNAPQRKIIHVDCDCFYAAIEMRDDPSLRDVPLAVGGRPETRGVVATCNYIARRYGVHSAMSSARALRLCPELLIVPPDM
ARYRLASQQIMAIYQRYTEVIEPLSLDEAYLDVTGQPHERGSATLMAEAIRRQIRDEVGITASAGIAPNKFLAKVASDWN
KPDGQYLIRPRDIDAFVAVLPVEKIHGVGRVTAERLHRLGIRSCGDLRRWSPADLFRHFGSFGERLLALAHGRDERPVST
DRSRKTISVEETYAQDLPDLASCLSKLPELVDRLQARLARSGSPAFKGLSVKLKFDDFSQTTVEQPGYALSMAAFGQLLR
AGHARGARPARLLGVGVKLADDFDLPRQLRLFGRDGRPLPDSAPPAEAPPGGPEADSAA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=371, Percent_Identity=30.4582210242588, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI7706681, Length=372, Percent_Identity=30.3763440860215, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI154350220, Length=318, Percent_Identity=31.1320754716981, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI5729982, Length=321, Percent_Identity=28.6604361370716, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=46.9565217391304, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=48.7106017191977, Blast_Score=317, Evalue=9e-88,
Organism=Escherichia coli, GI1787432, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17537959, Length=261, Percent_Identity=28.3524904214559, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193205700, Length=109, Percent_Identity=41.2844036697248, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193205702, Length=175, Percent_Identity=34.2857142857143, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=129, Percent_Identity=34.8837209302326, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=328, Percent_Identity=27.1341463414634, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355641, Length=287, Percent_Identity=33.1010452961672, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24644984, Length=287, Percent_Identity=33.1010452961672, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24668444, Length=127, Percent_Identity=37.007874015748, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41654; Mature: 41654

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPQRKIIHVDCDCFYAAIEMRDDPSLRDVPLAVGGRPETRGVVATCNYIARRYGVHSA
CCCCCCCEEEEECCEEEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
MSSARALRLCPELLIVPPDMARYRLASQQIMAIYQRYTEVIEPLSLDEAYLDVTGQPHER
HHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCC
GSATLMAEAIRRQIRDEVGITASAGIAPNKFLAKVASDWNKPDGQYLIRPRDIDAFVAVL
CHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
PVEKIHGVGRVTAERLHRLGIRSCGDLRRWSPADLFRHFGSFGERLLALAHGRDERPVST
HHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DRSRKTISVEETYAQDLPDLASCLSKLPELVDRLQARLARSGSPAFKGLSVKLKFDDFSQ
CCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCH
TTVEQPGYALSMAAFGQLLRAGHARGARPARLLGVGVKLADDFDLPRQLRLFGRDGRPLP
HHHCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHEECCEECCCCCCCHHHHHHCCCCCCCC
DSAPPAEAPPGGPEADSAA
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAPQRKIIHVDCDCFYAAIEMRDDPSLRDVPLAVGGRPETRGVVATCNYIARRYGVHSA
CCCCCCCEEEEECCEEEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
MSSARALRLCPELLIVPPDMARYRLASQQIMAIYQRYTEVIEPLSLDEAYLDVTGQPHER
HHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCC
GSATLMAEAIRRQIRDEVGITASAGIAPNKFLAKVASDWNKPDGQYLIRPRDIDAFVAVL
CHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
PVEKIHGVGRVTAERLHRLGIRSCGDLRRWSPADLFRHFGSFGERLLALAHGRDERPVST
HHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DRSRKTISVEETYAQDLPDLASCLSKLPELVDRLQARLARSGSPAFKGLSVKLKFDDFSQ
CCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCH
TTVEQPGYALSMAAFGQLLRAGHARGARPARLLGVGVKLADDFDLPRQLRLFGRDGRPLP
HHHCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHEECCEECCCCCCCHHHHHHCCCCCCCC
DSAPPAEAPPGGPEADSAA
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA