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The map label for this gene is ureC [H]

Identifier: 33864500

GI number: 33864500

Start: 2361109

End: 2362833

Strand: Direct

Name: ureC [H]

Synonym: PMT2236

Alternate gene names: 33864500

Gene position: 2361109-2362833 (Clockwise)

Preceding gene: 33864499

Following gene: 33864503

Centisome position: 97.94

GC content: 56.17

Gene sequence:

>1725_bases
ATGGCCTACCGGATCGATCGCCAGGCCTACGCCGAAACCTACGGCCCCACCACAGGTGACCGCATACGCCTAGCAGACAC
CGAGTTGATCCTGGAGGTGGAACGCGATTTCACCACCTACGGCGAAGAAGTCAAATTCGGTGGAGGGAAAGTGATCCGCG
ACGGCATGGGGCAATCCCAGCAATCCCGCGCCAATGGTGCTGTTGACACCGTGATCACCAATGCCCTGATCCTCGACTGG
TGGGGGATCGTCAAAGCAGATATCGGCCTAAGAGACGGACGGATCGTTGCCATCGGCAAGGCTGGCAATCCCGACATCAC
TGACGGGATTGACATTGTGATCGGCCCAGGCACTGAAGCCATTGCTGGAGAGGGTCACATCGTGACCGCCGGCGCCATCG
ATAGCCACATCCATTTCATTTGCCCACAGCAAATCGAGACTGCCCTGGCTAGCGGCGTTACCACCATGCTCGGTGGTGGT
ACAGGTCCGGCAACAGGCACCAATGCCACTACCTGTACACCTGGCGCCTTTCACATCAGCCGCATGCTGCAAGCAGCCGA
AGGCTTGCCGATGAATCTTGGCTTCTTTGGTAAAGGCAATGCCAGTACAGCTGAAGCTCTCGAGGAGCAAGTACTAGCCG
GTGCCTGCGGCCTCAAACTCCACGAAGACTGGGGTACCACTCCAGCAGCTATTGACTGCTGTCTTTCGGTAGCCGATCGC
TTTGATGTCCAGGTCTGCATCCACACAGACACGCTCAATGAAGCAGGTTTTGTAGAAGACACAATCCGAGCCATCGGCGG
ACGCACCATCCACACCTTCCATACCGAAGGGGCCGGTGGAGGCCATGCACCAGACATCATCCGTATCTGTGGTGAAAGCA
ACGTGCTGCCCAGCTCCACAAATCCAACCCGGCCTTACACCCGCAACACCCTGGAAGAGCACCTCGACATGCTCATGGTT
TGCCACCACCTAGATCCAGCGATTCCTGAAGATGTGGCCTTTGCCGAATCGCGCATCCGTCGCGAAACGATCGCTGCGGA
AGATATTCTCCACGACCTCGGTGCCTTCAGCATCATTGCCAGTGATTCCCAAGCGATGGGACGAGTCGGAGAGGTGATTA
CCAGAACATTCCAGACCGCTCACAAGATGAAAGTTCAGAGAGGCCCTCTGCCAGAAGATGCTGCCAATCCACGTGGCAGT
CGTAACGACAACAACCGCATAAAGCGCTACATCGCCAAAGTAACGATCAACCCCGCCATTGCCCACGGCATTGACAACCA
TGTTGGCTCAGTAGAGGTAGGCAAACTGGCAGACCTGGTGCTCTGGAAGCCAGGCTTCTTCGGCGTGCGGCCAGAACTTG
TCATCAAGGGCGGGTCAATCATCTGGGCGCAAATGGGCGATGCTAATGCCTCGATTCCAACACCTGGACCAGTCCATGGC
AGACCAATGTTTGCAGCATTCGGCAAAGCCCTTGCCCCCAGCTGCCTCACCTTCCTGAGCCAAGCGGCCATCGAAACAGA
TCTTCCCAACAAGCTGGGGCTGCAACGTGCCTGCATTCCCGTTCTGAACACCCGCACGATCGGCAAAGCAGAAATGCACA
ACAACAATTCACTACCAAAAGTAGAGGTAGATCCACAAACTTACGAGGTGTTCGCCGACGGCGATTTACTCACATGCGAC
CCCGCAGAAGAACTGCCAATGGCCCAGCGATATCTCCTACTTTAA

Upstream 100 bases:

>100_bases
TGCCCTTGCTGGTCACCGCAAGGTTTTTGGTTTCAACGGTCTGGTCAACGGACCCCTCGACTGAACTGCTTCTACACCTC
GTCCCTTTCGCTGCATTGCT

Downstream 100 bases:

>100_bases
ACGCTAAATTCAACATCTACCTTTAGGTTGCTAAGTAATAGATCAAGACTTGATCGGCATCACAACCTCAGCCGGCTGAG
GAGCACACTCTGCAACCTGT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MAYRIDRQAYAETYGPTTGDRIRLADTELILEVERDFTTYGEEVKFGGGKVIRDGMGQSQQSRANGAVDTVITNALILDW
WGIVKADIGLRDGRIVAIGKAGNPDITDGIDIVIGPGTEAIAGEGHIVTAGAIDSHIHFICPQQIETALASGVTTMLGGG
TGPATGTNATTCTPGAFHISRMLQAAEGLPMNLGFFGKGNASTAEALEEQVLAGACGLKLHEDWGTTPAAIDCCLSVADR
FDVQVCIHTDTLNEAGFVEDTIRAIGGRTIHTFHTEGAGGGHAPDIIRICGESNVLPSSTNPTRPYTRNTLEEHLDMLMV
CHHLDPAIPEDVAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLPEDAANPRGS
RNDNNRIKRYIAKVTINPAIAHGIDNHVGSVEVGKLADLVLWKPGFFGVRPELVIKGGSIIWAQMGDANASIPTPGPVHG
RPMFAAFGKALAPSCLTFLSQAAIETDLPNKLGLQRACIPVLNTRTIGKAEMHNNNSLPKVEVDPQTYEVFADGDLLTCD
PAEELPMAQRYLLL

Sequences:

>Translated_574_residues
MAYRIDRQAYAETYGPTTGDRIRLADTELILEVERDFTTYGEEVKFGGGKVIRDGMGQSQQSRANGAVDTVITNALILDW
WGIVKADIGLRDGRIVAIGKAGNPDITDGIDIVIGPGTEAIAGEGHIVTAGAIDSHIHFICPQQIETALASGVTTMLGGG
TGPATGTNATTCTPGAFHISRMLQAAEGLPMNLGFFGKGNASTAEALEEQVLAGACGLKLHEDWGTTPAAIDCCLSVADR
FDVQVCIHTDTLNEAGFVEDTIRAIGGRTIHTFHTEGAGGGHAPDIIRICGESNVLPSSTNPTRPYTRNTLEEHLDMLMV
CHHLDPAIPEDVAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLPEDAANPRGS
RNDNNRIKRYIAKVTINPAIAHGIDNHVGSVEVGKLADLVLWKPGFFGVRPELVIKGGSIIWAQMGDANASIPTPGPVHG
RPMFAAFGKALAPSCLTFLSQAAIETDLPNKLGLQRACIPVLNTRTIGKAEMHNNNSLPKVEVDPQTYEVFADGDLLTCD
PAEELPMAQRYLLL
>Mature_573_residues
AYRIDRQAYAETYGPTTGDRIRLADTELILEVERDFTTYGEEVKFGGGKVIRDGMGQSQQSRANGAVDTVITNALILDWW
GIVKADIGLRDGRIVAIGKAGNPDITDGIDIVIGPGTEAIAGEGHIVTAGAIDSHIHFICPQQIETALASGVTTMLGGGT
GPATGTNATTCTPGAFHISRMLQAAEGLPMNLGFFGKGNASTAEALEEQVLAGACGLKLHEDWGTTPAAIDCCLSVADRF
DVQVCIHTDTLNEAGFVEDTIRAIGGRTIHTFHTEGAGGGHAPDIIRICGESNVLPSSTNPTRPYTRNTLEEHLDMLMVC
HHLDPAIPEDVAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLPEDAANPRGSR
NDNNRIKRYIAKVTINPAIAHGIDNHVGSVEVGKLADLVLWKPGFFGVRPELVIKGGSIIWAQMGDANASIPTPGPVHGR
PMFAAFGKALAPSCLTFLSQAAIETDLPNKLGLQRACIPVLNTRTIGKAEMHNNNSLPKVEVDPQTYEVFADGDLLTCDP
AEELPMAQRYLLL

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 61300; Mature: 61169

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRIDRQAYAETYGPTTGDRIRLADTELILEVERDFTTYGEEVKFGGGKVIRDGMGQSQ
CCEECCHHHHHHHCCCCCCCEEEEECCEEEEEEHHHHHHCCCEEECCCCEEECCCCCCCH
QSRANGAVDTVITNALILDWWGIVKADIGLRDGRIVAIGKAGNPDITDGIDIVIGPGTEA
HHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCE
IAGEGHIVTAGAIDSHIHFICPQQIETALASGVTTMLGGGTGPATGTNATTCTPGAFHIS
ECCCCEEEEECCCCCCEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCHHHHHH
RMLQAAEGLPMNLGFFGKGNASTAEALEEQVLAGACGLKLHEDWGTTPAAIDCCLSVADR
HHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHC
FDVQVCIHTDTLNEAGFVEDTIRAIGGRTIHTFHTEGAGGGHAPDIIRICGESNVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHEECCCCCCCCCCC
NPTRPYTRNTLEEHLDMLMVCHHLDPAIPEDVAFAESRIRRETIAAEDILHDLGAFSIIA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
SDSQAMGRVGEVITRTFQTAHKMKVQRGPLPEDAANPRGSRNDNNRIKRYIAKVTINPAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCHHH
AHGIDNHVGSVEVGKLADLVLWKPGFFGVRPELVIKGGSIIWAQMGDANASIPTPGPVHG
HHCCCCCCCCEEHHHHHHEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCC
RPMFAAFGKALAPSCLTFLSQAAIETDLPNKLGLQRACIPVLNTRTIGKAEMHNNNSLPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCCCCCHHHCCCCCCCE
VEVDPQTYEVFADGDLLTCDPAEELPMAQRYLLL
EEECCCEEEEEECCCEEECCCHHHCCHHHHHHCC
>Mature Secondary Structure 
AYRIDRQAYAETYGPTTGDRIRLADTELILEVERDFTTYGEEVKFGGGKVIRDGMGQSQ
CEECCHHHHHHHCCCCCCCEEEEECCEEEEEEHHHHHHCCCEEECCCCEEECCCCCCCH
QSRANGAVDTVITNALILDWWGIVKADIGLRDGRIVAIGKAGNPDITDGIDIVIGPGTEA
HHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCE
IAGEGHIVTAGAIDSHIHFICPQQIETALASGVTTMLGGGTGPATGTNATTCTPGAFHIS
ECCCCEEEEECCCCCCEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCHHHHHH
RMLQAAEGLPMNLGFFGKGNASTAEALEEQVLAGACGLKLHEDWGTTPAAIDCCLSVADR
HHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHC
FDVQVCIHTDTLNEAGFVEDTIRAIGGRTIHTFHTEGAGGGHAPDIIRICGESNVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHEECCCCCCCCCCC
NPTRPYTRNTLEEHLDMLMVCHHLDPAIPEDVAFAESRIRRETIAAEDILHDLGAFSIIA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
SDSQAMGRVGEVITRTFQTAHKMKVQRGPLPEDAANPRGSRNDNNRIKRYIAKVTINPAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCHHH
AHGIDNHVGSVEVGKLADLVLWKPGFFGVRPELVIKGGSIIWAQMGDANASIPTPGPVHG
HHCCCCCCCCEEHHHHHHEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCC
RPMFAAFGKALAPSCLTFLSQAAIETDLPNKLGLQRACIPVLNTRTIGKAEMHNNNSLPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCCCCCHHHCCCCCCCE
VEVDPQTYEVFADGDLLTCDPAEELPMAQRYLLL
EEECCCEEEEEECCCEEECCCHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA