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The map label for this gene is queC

Identifier: 33864486

GI number: 33864486

Start: 2349359

End: 2350048

Strand: Direct

Name: queC

Synonym: PMT2222

Alternate gene names: 33864486

Gene position: 2349359-2350048 (Clockwise)

Preceding gene: 33864484

Following gene: 33864487

Centisome position: 97.45

GC content: 52.9

Gene sequence:

>690_bases
ATGTCCAGCATGATCCACTCAACAACCATTGCCCTGCTATCAGGAGGTCTTGATTCCGCCACTGCCGCTGCCTTGGCAGT
GGAAGCAGGTCAAAAGGTCATCGGACTTTCGTTCGATTACGGGCAACGACATCGCAAAGAACTGCAAGCCGCTGACGCGC
TGGCGGCCCACATGGGTCTAAGCGAACACCATGTAATCAGTGTCAACCTTGGCAGTTGGGGAGGCTCCTCCCTCACCGAT
CTAACGCAAACAGTACCCAGTGAAGGAGTCGTTGACGGAGTGATCCCCAACACTTACGTACCTGGACGCAACACGGTCTT
CATTGCCATTGGCCTCAGTCTTGCCGAAGCACGTAATGCCAATCAGCTGGTGTTAGGGATAAATGCAATGGACTACTCCG
GCTATCCAGACTGCAGACCTGACTATCTCAGGGCCTATCAGAGCTTGGCTGATCTGGCGAATAAAGCTGGCCGTGAAGGA
CATGGAATCAAACTCTGGGCTCCTTTAATTGATTGGAACAAGAAACAAATTGTGCAAGAAGCACTTCGACTCGGAGTACC
GATCGATAAAACCTGGAGCTGCTATAGCGGAGGCGATCATGCCTGCGGTATATGCGACAGCTGCCGCATCCGCGATGCAG
CTTTGAGCGAGGCTGGCAGATCAGATCTCTGCAGCAAGTCAACACCATGA

Upstream 100 bases:

>100_bases
TTGCCCGCAGGGGTTCCAACACTGTCGTCGACCACAAAACAACCAGCCCGAAAAAGATTCTGTTCTGAATTGATGCCTGC
ATACCAACAAGCGCTAGAGA

Downstream 100 bases:

>100_bases
CTTCTCTAGAGCGGCGACTTTGCCGCTGGCAAGAACCAGCGAAGTTGGCAAAACAACTCACCAAAACTTGGGGAGAAGCT
GGGCTTGTCTGGCTGGATGG

Product: ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSSMIHSTTIALLSGGLDSATAAALAVEAGQKVIGLSFDYGQRHRKELQAADALAAHMGLSEHHVISVNLGSWGGSSLTD
LTQTVPSEGVVDGVIPNTYVPGRNTVFIAIGLSLAEARNANQLVLGINAMDYSGYPDCRPDYLRAYQSLADLANKAGREG
HGIKLWAPLIDWNKKQIVQEALRLGVPIDKTWSCYSGGDHACGICDSCRIRDAALSEAGRSDLCSKSTP

Sequences:

>Translated_229_residues
MSSMIHSTTIALLSGGLDSATAAALAVEAGQKVIGLSFDYGQRHRKELQAADALAAHMGLSEHHVISVNLGSWGGSSLTD
LTQTVPSEGVVDGVIPNTYVPGRNTVFIAIGLSLAEARNANQLVLGINAMDYSGYPDCRPDYLRAYQSLADLANKAGREG
HGIKLWAPLIDWNKKQIVQEALRLGVPIDKTWSCYSGGDHACGICDSCRIRDAALSEAGRSDLCSKSTP
>Mature_228_residues
SSMIHSTTIALLSGGLDSATAAALAVEAGQKVIGLSFDYGQRHRKELQAADALAAHMGLSEHHVISVNLGSWGGSSLTDL
TQTVPSEGVVDGVIPNTYVPGRNTVFIAIGLSLAEARNANQLVLGINAMDYSGYPDCRPDYLRAYQSLADLANKAGREGH
GIKLWAPLIDWNKKQIVQEALRLGVPIDKTWSCYSGGDHACGICDSCRIRDAALSEAGRSDLCSKSTP

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=214, Percent_Identity=34.5794392523364, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PROMM (Q7V3W6)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_896046.1
- ProteinModelPortal:   Q7V3W6
- SMR:   Q7V3W6
- STRING:   Q7V3W6
- GeneID:   1728067
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT2222
- NMPDR:   fig|74547.1.peg.2213
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK922374
- BioCyc:   PMAR74547:PMT2222-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24268; Mature: 24136

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMIHSTTIALLSGGLDSATAAALAVEAGQKVIGLSFDYGQRHRKELQAADALAAHMGL
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCC
SEHHVISVNLGSWGGSSLTDLTQTVPSEGVVDGVIPNTYVPGRNTVFIAIGLSLAEARNA
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHCCCC
NQLVLGINAMDYSGYPDCRPDYLRAYQSLADLANKAGREGHGIKLWAPLIDWNKKQIVQE
CEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
ALRLGVPIDKTWSCYSGGDHACGICDSCRIRDAALSEAGRSDLCSKSTP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
SSMIHSTTIALLSGGLDSATAAALAVEAGQKVIGLSFDYGQRHRKELQAADALAAHMGL
CCHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCC
SEHHVISVNLGSWGGSSLTDLTQTVPSEGVVDGVIPNTYVPGRNTVFIAIGLSLAEARNA
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHCCCC
NQLVLGINAMDYSGYPDCRPDYLRAYQSLADLANKAGREGHGIKLWAPLIDWNKKQIVQE
CEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
ALRLGVPIDKTWSCYSGGDHACGICDSCRIRDAALSEAGRSDLCSKSTP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642