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The map label for this gene is speA [H]

Identifier: 33864414

GI number: 33864414

Start: 2267235

End: 2269181

Strand: Direct

Name: speA [H]

Synonym: PMT2150

Alternate gene names: 33864414

Gene position: 2267235-2269181 (Clockwise)

Preceding gene: 33864413

Following gene: 33864416

Centisome position: 94.04

GC content: 54.44

Gene sequence:

>1947_bases
ATGTCGGCAGCCGACCCCATCCAGGACAACAAGTCATGGACCGTTGCAGACAGTGCAGCTCTCTATGGCCTCGATCACTG
GGGACACCCTTACTTCTCAGCCAACGCTAACGGCCACGTGCAGGTCCAGCCACGCGGCGATCAAGGCAGCTGCCTGGATC
TGGTGGAACTGGTAGAGGAGCTCAAAAGCCGTAACCTCAACTTGCCTCTGCTGATCCGCTTTGATGACATCCTCGAAGAC
CGGCTAGAGAGGCTGCACAGCGCCTTCGAAGAAGCTATTAGCAAATACGGATACGCCGGTCGATATCAAGGCGTATTCCC
GGTGAAGTGCAACCAACAGCGCCACGTCGTAGAACAACTGGTAGAAAGTGGTCGCCAATGGCACTTTGGCCTAGAGGCTG
GCAGCAAGGCTGAGCTGCTGATTGCTCTTTCACTCGTCAACGACCCAGAGGCACTACTGATCTGTAACGGCTACAAAGAT
CAGCGCTACATCGAAACCGCGATCCTGGCCCGCAGGCTTGGTCGCCAACCTGTGGTAGTGATTGAACAACCCGATGAAGT
GGAACGGATTATCCGCTCCAGCCAAGAACTTGGCGCAGCACCCTTCCTCGGTGTACGAGCAAAGCTAACGACACGCAGTA
CGGGCCACTGGAGTAGCTCAGTAGGCGAGAAAGCCAAGTTCGGTCTCTCAGTGCCGGATCTGCTAGCCACAGTGGAAGCC
TTAAGACAAGCTGATCTACTTAGCGATCTGCGCCTACTGCACTTCCACATCGGGAGCCAAATCAACGACATCGCTGTACT
CAAAGACGCGCTTCAAGAGGCAGCGCAAATTTACGTAGAGCTGACCAAGCTGGGAGCCCCCATGGGGTATTTGGATGTTG
GGGGTGGTCTGGGTGTCGACTACGACGGCAGCCGCAGCGCTAGCGCAGCATCGACCAACTACTCCCTACAAAACTACGCC
AATGATGTAGTCGCAACGGTGCGCGAATGCTGTAAACCCCATGGCATCACTTTGCCTATCCTTGTGAGCGAAAGCGGACG
CGCGATCGCTAGTCATTTCTCAATACTCGTGTTCGATGTACTGGGTACAGGAACTGTCCCAGGAGCTATCCCCAAGCAAA
CAGTAGAGGAACCCCTCACCATTCACAACCTTAGGGAGACGCTCTCAGGAGTTATGGCAACTCAAAAGGGTGCTGTATCT
GAAATATCGCGCCTACAGGAAGCATGGAACGACGCGATCAAATTCAAAGAAGATGCCCTCGCCGCCTTCCGCTTGGGTTA
CATCAGCCTGCCAGAGCGGGCTCTGGCAGAACAACTTACAGGGGCTTGCGCCGAAGCAATTATGGGCCAATTGCCTTGCA
ACGAAACAATTCCCGACGACTTACAAAGTTTAAGAGCTGTTCTCGCTAGCACCTACTACGCCAACCTTTCAATATTTCGT
TCAGCCCCAGACACCTGGGCCATCGAACAACTCTTCCCGCTCATGCCGATTCATCGATTGAATGAAGAGCCAACTCAGCT
AGGTCACTTCGCTGACCTCACCTGCGACTCCGACGGCAAACTGGACCGCTTCATCGGGAATGGGCAAACCAAAACTCTGC
TGGAGCTTCACAACCTGCGCCAAAACGAGGCTTACATGATTGGCATGTTTCTCGCCGGTGCTTACCAGGAAGTGATGGGC
AATCTGCACAACCTGTTCGGCAGTACCAATGCAGTGCACATCCGTTTAACAACTGCTGGTGGCTACCAGGTGGACCACGT
TGTGCGAGGCAACACCAATTCCGAGGTGCTCGAAGCCATGGAGCACAACCCTGAGCTCCTGCTAGAGAGGCTGCGCTTGG
CTAGTGAACTTGCGATTCAACGAGGTGAGCTAAAGATCAACGATGTGCGCCGGCTGATGGACCATCTAGAAGCGAGCCTG
CGTCAGACCACGTACCTTCAAGGCTAG

Upstream 100 bases:

>100_bases
CCACTATTGAGCGGGAGGGATCCTGATACCAAGAAGAATCGAATGCCAAAGCACACCTAGATTTCCTTGTCATTCCCTCC
GCGATCCATCTGCGTGCGTT

Downstream 100 bases:

>100_bases
GACTTAACATCATTCCCATATCGGCGACATGAGCAACTTTGATCACAGCAACTCATTGAGTGCTGAAGAGTCGCATCCCT
CGAGATCAGCAACTTGTTTT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MSAADPIQDNKSWTVADSAALYGLDHWGHPYFSANANGHVQVQPRGDQGSCLDLVELVEELKSRNLNLPLLIRFDDILED
RLERLHSAFEEAISKYGYAGRYQGVFPVKCNQQRHVVEQLVESGRQWHFGLEAGSKAELLIALSLVNDPEALLICNGYKD
QRYIETAILARRLGRQPVVVIEQPDEVERIIRSSQELGAAPFLGVRAKLTTRSTGHWSSSVGEKAKFGLSVPDLLATVEA
LRQADLLSDLRLLHFHIGSQINDIAVLKDALQEAAQIYVELTKLGAPMGYLDVGGGLGVDYDGSRSASAASTNYSLQNYA
NDVVATVRECCKPHGITLPILVSESGRAIASHFSILVFDVLGTGTVPGAIPKQTVEEPLTIHNLRETLSGVMATQKGAVS
EISRLQEAWNDAIKFKEDALAAFRLGYISLPERALAEQLTGACAEAIMGQLPCNETIPDDLQSLRAVLASTYYANLSIFR
SAPDTWAIEQLFPLMPIHRLNEEPTQLGHFADLTCDSDGKLDRFIGNGQTKTLLELHNLRQNEAYMIGMFLAGAYQEVMG
NLHNLFGSTNAVHIRLTTAGGYQVDHVVRGNTNSEVLEAMEHNPELLLERLRLASELAIQRGELKINDVRRLMDHLEASL
RQTTYLQG

Sequences:

>Translated_648_residues
MSAADPIQDNKSWTVADSAALYGLDHWGHPYFSANANGHVQVQPRGDQGSCLDLVELVEELKSRNLNLPLLIRFDDILED
RLERLHSAFEEAISKYGYAGRYQGVFPVKCNQQRHVVEQLVESGRQWHFGLEAGSKAELLIALSLVNDPEALLICNGYKD
QRYIETAILARRLGRQPVVVIEQPDEVERIIRSSQELGAAPFLGVRAKLTTRSTGHWSSSVGEKAKFGLSVPDLLATVEA
LRQADLLSDLRLLHFHIGSQINDIAVLKDALQEAAQIYVELTKLGAPMGYLDVGGGLGVDYDGSRSASAASTNYSLQNYA
NDVVATVRECCKPHGITLPILVSESGRAIASHFSILVFDVLGTGTVPGAIPKQTVEEPLTIHNLRETLSGVMATQKGAVS
EISRLQEAWNDAIKFKEDALAAFRLGYISLPERALAEQLTGACAEAIMGQLPCNETIPDDLQSLRAVLASTYYANLSIFR
SAPDTWAIEQLFPLMPIHRLNEEPTQLGHFADLTCDSDGKLDRFIGNGQTKTLLELHNLRQNEAYMIGMFLAGAYQEVMG
NLHNLFGSTNAVHIRLTTAGGYQVDHVVRGNTNSEVLEAMEHNPELLLERLRLASELAIQRGELKINDVRRLMDHLEASL
RQTTYLQG
>Mature_647_residues
SAADPIQDNKSWTVADSAALYGLDHWGHPYFSANANGHVQVQPRGDQGSCLDLVELVEELKSRNLNLPLLIRFDDILEDR
LERLHSAFEEAISKYGYAGRYQGVFPVKCNQQRHVVEQLVESGRQWHFGLEAGSKAELLIALSLVNDPEALLICNGYKDQ
RYIETAILARRLGRQPVVVIEQPDEVERIIRSSQELGAAPFLGVRAKLTTRSTGHWSSSVGEKAKFGLSVPDLLATVEAL
RQADLLSDLRLLHFHIGSQINDIAVLKDALQEAAQIYVELTKLGAPMGYLDVGGGLGVDYDGSRSASAASTNYSLQNYAN
DVVATVRECCKPHGITLPILVSESGRAIASHFSILVFDVLGTGTVPGAIPKQTVEEPLTIHNLRETLSGVMATQKGAVSE
ISRLQEAWNDAIKFKEDALAAFRLGYISLPERALAEQLTGACAEAIMGQLPCNETIPDDLQSLRAVLASTYYANLSIFRS
APDTWAIEQLFPLMPIHRLNEEPTQLGHFADLTCDSDGKLDRFIGNGQTKTLLELHNLRQNEAYMIGMFLAGAYQEVMGN
LHNLFGSTNAVHIRLTTAGGYQVDHVVRGNTNSEVLEAMEHNPELLLERLRLASELAIQRGELKINDVRRLMDHLEASLR
QTTYLQG

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=631, Percent_Identity=36.4500792393027, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71365; Mature: 71234

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAADPIQDNKSWTVADSAALYGLDHWGHPYFSANANGHVQVQPRGDQGSCLDLVELVEE
CCCCCCCCCCCCEEEECCHHHCCCCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHH
LKSRNLNLPLLIRFDDILEDRLERLHSAFEEAISKYGYAGRYQGVFPVKCNQQRHVVEQL
HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHH
VESGRQWHFGLEAGSKAELLIALSLVNDPEALLICNGYKDQRYIETAILARRLGRQPVVV
HHCCCCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
IEQPDEVERIIRSSQELGAAPFLGVRAKLTTRSTGHWSSSVGEKAKFGLSVPDLLATVEA
EECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHCCCHHHCCCCHHHHHHHHHH
LRQADLLSDLRLLHFHIGSQINDIAVLKDALQEAAQIYVELTKLGAPMGYLDVGGGLGVD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
YDGSRSASAASTNYSLQNYANDVVATVRECCKPHGITLPILVSESGRAIASHFSILVFDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LGTGTVPGAIPKQTVEEPLTIHNLRETLSGVMATQKGAVSEISRLQEAWNDAIKFKEDAL
HCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AAFRLGYISLPERALAEQLTGACAEAIMGQLPCNETIPDDLQSLRAVLASTYYANLSIFR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
SAPDTWAIEQLFPLMPIHRLNEEPTQLGHFADLTCDSDGKLDRFIGNGQTKTLLELHNLR
CCCCCHHHHHHHHHCCHHHCCCCHHHHCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHCC
QNEAYMIGMFLAGAYQEVMGNLHNLFGSTNAVHIRLTTAGGYQVDHVVRGNTNSEVLEAM
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEECCCHHHHHHHH
EHNPELLLERLRLASELAIQRGELKINDVRRLMDHLEASLRQTTYLQG
HCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAADPIQDNKSWTVADSAALYGLDHWGHPYFSANANGHVQVQPRGDQGSCLDLVELVEE
CCCCCCCCCCCEEEECCHHHCCCCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHH
LKSRNLNLPLLIRFDDILEDRLERLHSAFEEAISKYGYAGRYQGVFPVKCNQQRHVVEQL
HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHH
VESGRQWHFGLEAGSKAELLIALSLVNDPEALLICNGYKDQRYIETAILARRLGRQPVVV
HHCCCCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
IEQPDEVERIIRSSQELGAAPFLGVRAKLTTRSTGHWSSSVGEKAKFGLSVPDLLATVEA
EECCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHCCCHHHCCCCHHHHHHHHHH
LRQADLLSDLRLLHFHIGSQINDIAVLKDALQEAAQIYVELTKLGAPMGYLDVGGGLGVD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
YDGSRSASAASTNYSLQNYANDVVATVRECCKPHGITLPILVSESGRAIASHFSILVFDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LGTGTVPGAIPKQTVEEPLTIHNLRETLSGVMATQKGAVSEISRLQEAWNDAIKFKEDAL
HCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AAFRLGYISLPERALAEQLTGACAEAIMGQLPCNETIPDDLQSLRAVLASTYYANLSIFR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
SAPDTWAIEQLFPLMPIHRLNEEPTQLGHFADLTCDSDGKLDRFIGNGQTKTLLELHNLR
CCCCCHHHHHHHHHCCHHHCCCCHHHHCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHCC
QNEAYMIGMFLAGAYQEVMGNLHNLFGSTNAVHIRLTTAGGYQVDHVVRGNTNSEVLEAM
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEECCCHHHHHHHH
EHNPELLLERLRLASELAIQRGELKINDVRRLMDHLEASLRQTTYLQG
HCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA