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The map label for this gene is cyaA [H]

Identifier: 33864416

GI number: 33864416

Start: 2270279

End: 2272192

Strand: Direct

Name: cyaA [H]

Synonym: PMT2152

Alternate gene names: 33864416

Gene position: 2270279-2272192 (Clockwise)

Preceding gene: 33864414

Following gene: 33864417

Centisome position: 94.17

GC content: 51.88

Gene sequence:

>1914_bases
ATGGTAACAAAGGGCAAGTGGATCAAGCGCCAAGCGGCTGTCTTAAGCCTTGGAGTGGTGATTGGCGGCATTGGATTGCT
CTATCCCAGCCAAATAGAGCTTCTTGAACTGGCATTTGTCGATGCTGCCCAAGAGCTTCGTGGCCCACGTCGGGTTCCTG
ATGGCATCACGATCGTGGCCATTGACGACTTCAGCCTGCAACAAGCATCCAATACAGATCTCAGTGAGAGAAGAGATTTA
CGTAGTTTGCAGCATTGGCCATGGCCGCGAAAAATCTACGCAACGGTTTTGGATCGCCTGTTTGCCTGTGGAGTGAAGGC
TGTTGCTGTTGACCTGCTCTTCGATAGCCCAAGTATCTATGGCCCAAATGACGATCAGGTCTTAGCCGTCAGCTTAAAGC
GCTTCCAACCCAAAGTAGTATTGGCAGCACAAGTGCTCGAAAGCCGTGGTGCTGTAGGAGGCCTAAGCCTTCTACGTGCC
ACCCCTGCACTTAGCGCTGCATTGGGAACAAACCAACACGGACTACTCAATGGATTCCAAGATGCTGATGGTGTGATCCG
CCAACGCCCGAATACCTACGCCACCACGGTCAGCAAGAGTCTTGGCAAAAACACTCCTCTTAGCCTTGGGGTTGCGCTCT
TACAAGCTGCAGAACTACCAGTGGAGCATCATGTGAAATGGGATGGTTGGTTGCCACTCCTCGATCCCTACGGCCCACCG
CGCACGATTCCGACACTTTCCATCTGGCAGCTGCTTGAGCCAAACAGCTATGCCGCATTGAAAGAGTCTGGGCAACTGCG
CGATCAACTCGTCCTAATCGGTCCAACGGCTACATCACTACAAGACTTACACCAAACAGCATTTGCAAGAGGTGCAGGCA
TGCCTGGCGTGGAAGTCCACGCGACGGAAATCGCCAATCAAATAGAAGGCCGCGCCCTGCTGTTCCCCCACAAATCGCCT
GGATGGTCGCTGTTGCTAGGAGTGATGGTGGTACTGATGGCTTTGGCCTCTCAGCGCTGGGAACGTCCTCTTACTCGCCT
GGGATTGCTGACGGCGATTGCTGCAGGCCTACTGCTACTAAGCCTCCTATTCATTGCCCTACTTGGCCTTGAGGTTGGTT
TGGTGAGCCTGTCTGCTGGAGCACTCGCAGCAGGAGTCATCAGTAGTGCTGGTGCCACATTGAAACTCCAATGGCAAAAA
CGACGCCTACGACAAAGCCTAGGGCGCTACTTATCACCAGCCGTAGCCGCGGAGATCGCCAATCAACCTGAGGAAGCAGA
TGACATCCTGGGTGGACGACTCACGGAAGTCGTGGTGTTAATGACCGATATTCGCAGCTTCACCAGCTTCACCCAATCCA
TGTCAGAAAGTGGTCAAGTACCCCGACTGGTTGAAAGGCTAAACCTCTATTTCTCGGAAGTTGTAGAAGCCATCCATCAA
CGGGGAGGCACGGTGGATAAATTCATTGGCGATGCCGCCTTGGCTGTTTTTGGAGCACCAATCAAGCGAAGCAGTCAGGT
GGATGCAAAAGCCGCCATCGAAGCAGCTTTAGATATCGAGAAACGGCTAGCAAAGCTCAATCAACACTGGAACAATAAAG
GTGAAAAATCCTGGGAACAGGTGGTTGTGCTTAGTTTTGGCACTGTGATCAGCGGCAACATTGGCTCCCGCAGCCGGATG
GATTACACGGTGATAGGCGATGCTGTCAACACTGCTAGCCGGCTCGAAAAAATAGCCAAACAAAGCAATCAAACAGTGGT
TATGAGCGAGGAAGTAGCTCAACTCCTCGGCGACCAATGGACCCTACAAAACTTAGGACTATATGAGATACGAGGCCAGA
AAGCACAGCACGTGTACGCGATTAAAAGCGTCCATAGCAAAGTCAAATTCCTGAATGAATCAAGTAAAGAATAA

Upstream 100 bases:

>100_bases
GCTTTCGATCTCAAGACAAAGCTGTTCCTGCCTAATGCAACAAGAGCTGGCTGTTCAGAACGACTCGCATCACGATGGTT
ATTAGCAGTCTTGAGCATGG

Downstream 100 bases:

>100_bases
AAAATACTAAAAGAGTTGATGATGAAGTTAGGGAAACGTTTCTTGTGGTTGATCGTATTACAAGGTTTGTTTAGCCCTGC
TTTCGCCTCATCCCTTAAGC

Product: guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MVTKGKWIKRQAAVLSLGVVIGGIGLLYPSQIELLELAFVDAAQELRGPRRVPDGITIVAIDDFSLQQASNTDLSERRDL
RSLQHWPWPRKIYATVLDRLFACGVKAVAVDLLFDSPSIYGPNDDQVLAVSLKRFQPKVVLAAQVLESRGAVGGLSLLRA
TPALSAALGTNQHGLLNGFQDADGVIRQRPNTYATTVSKSLGKNTPLSLGVALLQAAELPVEHHVKWDGWLPLLDPYGPP
RTIPTLSIWQLLEPNSYAALKESGQLRDQLVLIGPTATSLQDLHQTAFARGAGMPGVEVHATEIANQIEGRALLFPHKSP
GWSLLLGVMVVLMALASQRWERPLTRLGLLTAIAAGLLLLSLLFIALLGLEVGLVSLSAGALAAGVISSAGATLKLQWQK
RRLRQSLGRYLSPAVAAEIANQPEEADDILGGRLTEVVVLMTDIRSFTSFTQSMSESGQVPRLVERLNLYFSEVVEAIHQ
RGGTVDKFIGDAALAVFGAPIKRSSQVDAKAAIEAALDIEKRLAKLNQHWNNKGEKSWEQVVVLSFGTVISGNIGSRSRM
DYTVIGDAVNTASRLEKIAKQSNQTVVMSEEVAQLLGDQWTLQNLGLYEIRGQKAQHVYAIKSVHSKVKFLNESSKE

Sequences:

>Translated_637_residues
MVTKGKWIKRQAAVLSLGVVIGGIGLLYPSQIELLELAFVDAAQELRGPRRVPDGITIVAIDDFSLQQASNTDLSERRDL
RSLQHWPWPRKIYATVLDRLFACGVKAVAVDLLFDSPSIYGPNDDQVLAVSLKRFQPKVVLAAQVLESRGAVGGLSLLRA
TPALSAALGTNQHGLLNGFQDADGVIRQRPNTYATTVSKSLGKNTPLSLGVALLQAAELPVEHHVKWDGWLPLLDPYGPP
RTIPTLSIWQLLEPNSYAALKESGQLRDQLVLIGPTATSLQDLHQTAFARGAGMPGVEVHATEIANQIEGRALLFPHKSP
GWSLLLGVMVVLMALASQRWERPLTRLGLLTAIAAGLLLLSLLFIALLGLEVGLVSLSAGALAAGVISSAGATLKLQWQK
RRLRQSLGRYLSPAVAAEIANQPEEADDILGGRLTEVVVLMTDIRSFTSFTQSMSESGQVPRLVERLNLYFSEVVEAIHQ
RGGTVDKFIGDAALAVFGAPIKRSSQVDAKAAIEAALDIEKRLAKLNQHWNNKGEKSWEQVVVLSFGTVISGNIGSRSRM
DYTVIGDAVNTASRLEKIAKQSNQTVVMSEEVAQLLGDQWTLQNLGLYEIRGQKAQHVYAIKSVHSKVKFLNESSKE
>Mature_637_residues
MVTKGKWIKRQAAVLSLGVVIGGIGLLYPSQIELLELAFVDAAQELRGPRRVPDGITIVAIDDFSLQQASNTDLSERRDL
RSLQHWPWPRKIYATVLDRLFACGVKAVAVDLLFDSPSIYGPNDDQVLAVSLKRFQPKVVLAAQVLESRGAVGGLSLLRA
TPALSAALGTNQHGLLNGFQDADGVIRQRPNTYATTVSKSLGKNTPLSLGVALLQAAELPVEHHVKWDGWLPLLDPYGPP
RTIPTLSIWQLLEPNSYAALKESGQLRDQLVLIGPTATSLQDLHQTAFARGAGMPGVEVHATEIANQIEGRALLFPHKSP
GWSLLLGVMVVLMALASQRWERPLTRLGLLTAIAAGLLLLSLLFIALLGLEVGLVSLSAGALAAGVISSAGATLKLQWQK
RRLRQSLGRYLSPAVAAEIANQPEEADDILGGRLTEVVVLMTDIRSFTSFTQSMSESGQVPRLVERLNLYFSEVVEAIHQ
RGGTVDKFIGDAALAVFGAPIKRSSQVDAKAAIEAALDIEKRLAKLNQHWNNKGEKSWEQVVVLSFGTVISGNIGSRSRM
DYTVIGDAVNTASRLEKIAKQSNQTVVMSEEVAQLLGDQWTLQNLGLYEIRGQKAQHVYAIKSVHSKVKFLNESSKE

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 69075; Mature: 69075

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKGKWIKRQAAVLSLGVVIGGIGLLYPSQIELLELAFVDAAQELRGPRRVPDGITIVA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IDDFSLQQASNTDLSERRDLRSLQHWPWPRKIYATVLDRLFACGVKAVAVDLLFDSPSIY
ECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCC
GPNDDQVLAVSLKRFQPKVVLAAQVLESRGAVGGLSLLRATPALSAALGTNQHGLLNGFQ
CCCCCCEEEEEHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCC
DADGVIRQRPNTYATTVSKSLGKNTPLSLGVALLQAAELPVEHHVKWDGWLPLLDPYGPP
CCCHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCC
RTIPTLSIWQLLEPNSYAALKESGQLRDQLVLIGPTATSLQDLHQTAFARGAGMPGVEVH
CCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEH
ATEIANQIEGRALLFPHKSPGWSLLLGVMVVLMALASQRWERPLTRLGLLTAIAAGLLLL
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLFIALLGLEVGLVSLSAGALAAGVISSAGATLKLQWQKRRLRQSLGRYLSPAVAAEIA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHHH
NQPEEADDILGGRLTEVVVLMTDIRSFTSFTQSMSESGQVPRLVERLNLYFSEVVEAIHQ
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RGGTVDKFIGDAALAVFGAPIKRSSQVDAKAAIEAALDIEKRLAKLNQHWNNKGEKSWEQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VVVLSFGTVISGNIGSRSRMDYTVIGDAVNTASRLEKIAKQSNQTVVMSEEVAQLLGDQW
EEEEEECCEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCE
TLQNLGLYEIRGQKAQHVYAIKSVHSKVKFLNESSKE
ECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVTKGKWIKRQAAVLSLGVVIGGIGLLYPSQIELLELAFVDAAQELRGPRRVPDGITIVA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IDDFSLQQASNTDLSERRDLRSLQHWPWPRKIYATVLDRLFACGVKAVAVDLLFDSPSIY
ECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCC
GPNDDQVLAVSLKRFQPKVVLAAQVLESRGAVGGLSLLRATPALSAALGTNQHGLLNGFQ
CCCCCCEEEEEHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCC
DADGVIRQRPNTYATTVSKSLGKNTPLSLGVALLQAAELPVEHHVKWDGWLPLLDPYGPP
CCCHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCC
RTIPTLSIWQLLEPNSYAALKESGQLRDQLVLIGPTATSLQDLHQTAFARGAGMPGVEVH
CCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEH
ATEIANQIEGRALLFPHKSPGWSLLLGVMVVLMALASQRWERPLTRLGLLTAIAAGLLLL
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLFIALLGLEVGLVSLSAGALAAGVISSAGATLKLQWQKRRLRQSLGRYLSPAVAAEIA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHHH
NQPEEADDILGGRLTEVVVLMTDIRSFTSFTQSMSESGQVPRLVERLNLYFSEVVEAIHQ
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RGGTVDKFIGDAALAVFGAPIKRSSQVDAKAAIEAALDIEKRLAKLNQHWNNKGEKSWEQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VVVLSFGTVISGNIGSRSRMDYTVIGDAVNTASRLEKIAKQSNQTVVMSEEVAQLLGDQW
EEEEEECCEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCE
TLQNLGLYEIRGQKAQHVYAIKSVHSKVKFLNESSKE
ECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]