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The map label for this gene is fabD [H]

Identifier: 33864262

GI number: 33864262

Start: 2111624

End: 2112520

Strand: Direct

Name: fabD [H]

Synonym: PMT1997

Alternate gene names: 33864262

Gene position: 2111624-2112520 (Clockwise)

Preceding gene: 33864261

Following gene: 33864263

Centisome position: 87.59

GC content: 56.74

Gene sequence:

>897_bases
ATGTCGATCGCTTGGGTGTTCCCTGGTCAGGGCTCACAAAAGCTGGGCATGGCTGACCCGATCATCAGCCTGCCCGATGC
CGAAGAGCGCTTTGCCCTCGCCTCTCGACTACTGGGACGTGATCTCCTTGCGATTTGCCGTGGTAGCGACCAAACCAATC
ATGACCCGGCCGACCTTAATGACACCCGCAATACCCAACCCGCACTTTTTGTCGTTGAATCATTACTGGTGGATGAACTG
CGCAGGCAGGGTCGTGAGGCATCGCTCATCGCAGGGCACAGCCTGGGTGAACTTGTAGCCCTCTATGCGGCTGAGGTTTT
TGACGTAAACACCGCCCTGCTGCTTCTGCGACGCCGCTCAGAACTGATGGCCTCAGCCGGTGGTGGGGCCATGACAGCCA
TCTTGGGCTTTGACCGCACACAGCTAAAAGCTCTGGTAGCAGACACAGAAGGAGTCGTGATCGCCAATGACAACAGTGCT
GCCCAGGTGGTTTTATCCGGCACCCCAGAGGCTGTTAGCAAGGTCAGCAGCCAGCTGACCTGCAAGCGAGCGATTCCGTT
GCCAGTCTCGGGAGCCTTCCATTCGCCTTTCATGGCCACAGCGGCCACTGAATTTGCAGCTGAACTGGATCAAGTGACTT
TCAAAGACGCCCGTGTCCCCGTTCTCTGCAATGCCGATCCAATCCCAACCTGCGATGCCAACTTGCTTAAGCAACGGCTA
AAAGATCAAATGACAACAGGCGTCCGTTGGCGCGAAACGATGGATACCATGGCCAGCCAAGGCGTCAACACAGTGGTCGA
AATCGGCCCTGGCAATGTGCTGAGTGGTCTGGTCAAGCGATCTCTTCCAGGAGTTGCGACCATCCAGCTGAGCTGTGCTG
CAGACCTGGGGAATTGA

Upstream 100 bases:

>100_bases
ATCGCAAGCAGCGGTTTTGGAGCTGGTCTCAGTTGGGGTGCAGCATTAATCCGCTGGCATGGGCCCATCTAGGCTCGCGC
TAAATCGCTAGACCATTCTG

Downstream 100 bases:

>100_bases
ACTTTGACCCAAACCAAACCCCGCCTGAGCTCAAGCATGCCGGTGCTAATGACACCGCAGCCAAGTCTCACCTATCGACT
CGTGAGCTATCTACTGGTGT

Product: malonyl coenzyme A-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSIAWVFPGQGSQKLGMADPIISLPDAEERFALASRLLGRDLLAICRGSDQTNHDPADLNDTRNTQPALFVVESLLVDEL
RRQGREASLIAGHSLGELVALYAAEVFDVNTALLLLRRRSELMASAGGGAMTAILGFDRTQLKALVADTEGVVIANDNSA
AQVVLSGTPEAVSKVSSQLTCKRAIPLPVSGAFHSPFMATAATEFAAELDQVTFKDARVPVLCNADPIPTCDANLLKQRL
KDQMTTGVRWRETMDTMASQGVNTVVEIGPGNVLSGLVKRSLPGVATIQLSCAADLGN

Sequences:

>Translated_298_residues
MSIAWVFPGQGSQKLGMADPIISLPDAEERFALASRLLGRDLLAICRGSDQTNHDPADLNDTRNTQPALFVVESLLVDEL
RRQGREASLIAGHSLGELVALYAAEVFDVNTALLLLRRRSELMASAGGGAMTAILGFDRTQLKALVADTEGVVIANDNSA
AQVVLSGTPEAVSKVSSQLTCKRAIPLPVSGAFHSPFMATAATEFAAELDQVTFKDARVPVLCNADPIPTCDANLLKQRL
KDQMTTGVRWRETMDTMASQGVNTVVEIGPGNVLSGLVKRSLPGVATIQLSCAADLGN
>Mature_297_residues
SIAWVFPGQGSQKLGMADPIISLPDAEERFALASRLLGRDLLAICRGSDQTNHDPADLNDTRNTQPALFVVESLLVDELR
RQGREASLIAGHSLGELVALYAAEVFDVNTALLLLRRRSELMASAGGGAMTAILGFDRTQLKALVADTEGVVIANDNSAA
QVVLSGTPEAVSKVSSQLTCKRAIPLPVSGAFHSPFMATAATEFAAELDQVTFKDARVPVLCNADPIPTCDANLLKQRLK
DQMTTGVRWRETMDTMASQGVNTVVEIGPGNVLSGLVKRSLPGVATIQLSCAADLGN

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=302, Percent_Identity=29.8013245033113, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1787334, Length=290, Percent_Identity=41.3793103448276, Blast_Score=174, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71984332, Length=298, Percent_Identity=24.1610738255034, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665753, Length=299, Percent_Identity=32.1070234113712, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31583; Mature: 31451

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAWVFPGQGSQKLGMADPIISLPDAEERFALASRLLGRDLLAICRGSDQTNHDPADLN
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DTRNTQPALFVVESLLVDELRRQGREASLIAGHSLGELVALYAAEVFDVNTALLLLRRRS
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMASAGGGAMTAILGFDRTQLKALVADTEGVVIANDNSAAQVVLSGTPEAVSKVSSQLT
HHHHHCCCCCEEEEECCCHHHHHHHEECCCCEEEECCCCCEEEEECCCHHHHHHHHHHHH
CKRAIPLPVSGAFHSPFMATAATEFAAELDQVTFKDARVPVLCNADPIPTCDANLLKQRL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHH
KDQMTTGVRWRETMDTMASQGVNTVVEIGPGNVLSGLVKRSLPGVATIQLSCAADLGN
HHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SIAWVFPGQGSQKLGMADPIISLPDAEERFALASRLLGRDLLAICRGSDQTNHDPADLN
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DTRNTQPALFVVESLLVDELRRQGREASLIAGHSLGELVALYAAEVFDVNTALLLLRRRS
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMASAGGGAMTAILGFDRTQLKALVADTEGVVIANDNSAAQVVLSGTPEAVSKVSSQLT
HHHHHCCCCCEEEEECCCHHHHHHHEECCCCEEEECCCCCEEEEECCCHHHHHHHHHHHH
CKRAIPLPVSGAFHSPFMATAATEFAAELDQVTFKDARVPVLCNADPIPTCDANLLKQRL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHH
KDQMTTGVRWRETMDTMASQGVNTVVEIGPGNVLSGLVKRSLPGVATIQLSCAADLGN
HHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]