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The map label for this gene is rpaB [H]

Identifier: 33864259

GI number: 33864259

Start: 2108447

End: 2109193

Strand: Direct

Name: rpaB [H]

Synonym: PMT1994

Alternate gene names: 33864259

Gene position: 2108447-2109193 (Clockwise)

Preceding gene: 33864257

Following gene: 33864260

Centisome position: 87.46

GC content: 54.89

Gene sequence:

>747_bases
ATGACGGCCACCAGCCCATCTAAAGAGACGATCCTCGTGGTCGACGATGAGGCCAGCATTCGTCGGATCCTCGAAACCCG
TCTCTCGATGATCGGCTATCAAGTGTTCACGGCATGTGACGGCAACGAAGCTCTCGATATCTTCCACAACTGTGAGCCTG
ATCTTGTTGTGCTCGACGTGATGATGCCAAAGCTTGATGGCTATGGCGTTTGTCAAGAGCTTCGCAAAGAATCGGATGTG
CCGATCGTGATGCTCACGGCCCTTGGAGATGTCGCTGACAGAATCACGGGGCTTGAGCTGGGTGCAGACGACTACGTCGT
CAAACCCTTCAGCCCTAAGGAACTTGAAGCGCGCATACGCTGCGTGCTTCGACGAGTCGAGAAAGAGCACGTTGCCGGCA
TCCCTAACTCAGGGGTGATTCAAGTGGCTGAACTAAGAGTCGACACCAACAAGCGACAGGTTTTCCGAGGAGATGAGCGG
ATTCGCCTTACCGGTATGGAATTCAGCCTGCTTGAGCTACTGGTCAGCCGCTCAGGGGAGCCTTTCAGTCGCGGCGAAAT
CCTCAAGGAGGTATGGGGTTATACACCTGAACGACATGTAGACACCAGAGTCGTGGATGTTCATATTTCACGTCTTCGCT
CCAAACTCGAAGACGATCCCGCCAATCCCGAGCTGATCCTCACCGCTCGAGGTACCGGCTACCTGTTCCAGCGCATCATC
GACTCCCTTGCCCCCGAAGGACTCTGA

Upstream 100 bases:

>100_bases
TAAGATAGGTAAAGAAAGTTGGCTTTAAATGAACCAAAAGGCCGGTACGCCTTAACAGCTCTTATCTAAGATTCATTGAT
TGCAGCCGCCAAAGAAAAAA

Downstream 100 bases:

>100_bases
TTCCTCCACGGCCTCCGGGCCCCGGAGCAAGACCACCCGCCCCAGAGCCATTAGGCGTCTGGTGATCTGGTATCGCCGCA
ATGCTGCCGTTACCAGCCTG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTATSPSKETILVVDDEASIRRILETRLSMIGYQVFTACDGNEALDIFHNCEPDLVVLDVMMPKLDGYGVCQELRKESDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRVEKEHVAGIPNSGVIQVAELRVDTNKRQVFRGDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRII
DSLAPEGL

Sequences:

>Translated_248_residues
MTATSPSKETILVVDDEASIRRILETRLSMIGYQVFTACDGNEALDIFHNCEPDLVVLDVMMPKLDGYGVCQELRKESDV
PIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRVEKEHVAGIPNSGVIQVAELRVDTNKRQVFRGDER
IRLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRII
DSLAPEGL
>Mature_247_residues
TATSPSKETILVVDDEASIRRILETRLSMIGYQVFTACDGNEALDIFHNCEPDLVVLDVMMPKLDGYGVCQELRKESDVP
IVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRCVLRRVEKEHVAGIPNSGVIQVAELRVDTNKRQVFRGDERI
RLTGMEFSLLELLVSRSGEPFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRIID
SLAPEGL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=43.2314410480349, Blast_Score=173, Evalue=8e-45,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=41.4847161572052, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=37.0044052863436, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=39.4736842105263, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=39.8230088495575, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=36.1233480176211, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=38.1974248927039, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40.4347826086956, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=35.3191489361702, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.8947368421053, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.8888888888889, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.7719298245614, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=33.9130434782609, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=35.4700854700855, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=39.622641509434, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=119, Percent_Identity=35.2941176470588, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=28.9256198347107, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=109, Percent_Identity=36.697247706422, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27806; Mature: 27675

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSPSKETILVVDDEASIRRILETRLSMIGYQVFTACDGNEALDIFHNCEPDLVVLDV
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKESDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CVLRRVEKEHVAGIPNSGVIQVAELRVDTNKRQVFRGDERIRLTGMEFSLLELLVSRSGE
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHCCCCCEEEEECCHHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRII
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DSLAPEGL
HHHCCCCC
>Mature Secondary Structure 
TATSPSKETILVVDDEASIRRILETRLSMIGYQVFTACDGNEALDIFHNCEPDLVVLDV
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCCCEEEEEE
MMPKLDGYGVCQELRKESDVPIVMLTALGDVADRITGLELGADDYVVKPFSPKELEARIR
HHCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCCHHHHHHHH
CVLRRVEKEHVAGIPNSGVIQVAELRVDTNKRQVFRGDERIRLTGMEFSLLELLVSRSGE
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHCCCCCEEEEECCHHHHHHHHHHCCCC
PFSRGEILKEVWGYTPERHVDTRVVDVHISRLRSKLEDDPANPELILTARGTGYLFQRII
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
DSLAPEGL
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]