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The map label for this gene is kdsB [H]

Identifier: 33864180

GI number: 33864180

Start: 2019784

End: 2020599

Strand: Reverse

Name: kdsB [H]

Synonym: PMT1914

Alternate gene names: 33864180

Gene position: 2020599-2019784 (Counterclockwise)

Preceding gene: 33864181

Following gene: 33864176

Centisome position: 83.81

GC content: 52.33

Gene sequence:

>816_bases
ATGGGAGTTCAACGCAGTGTCGTGGCCGTGCCTGCAAGGCTTGAATCATCGCGATTGCCCAATAAGGTTCTGGCAGATAT
CGGCGGGATGCCAATGCTGCAGCGTGTTCTTGAGCGCTGCAGTCAGGCTCATGGGCCAAATGCAGTTGTCCTTTGCACGG
ATAGTGATCGATTGAAAGAGATGGCGGAAGACTGGGGTTTCTCGGTGTTGATGACTTCGGCTTCATGCAATTCAGGTAGC
GAAAGGATTGCTTCGGTTGCCGATCATTTGGTTGCCATGGCCTGGGATGAGCAAGCTGATGGTTGGGATCAGCAGCAGCA
GCAACAGCGGTTGGCTATGACTGCAGTGATCAATGTGCAAGGAGATCAGCCGTTCTTGGACCCTGCGGTGGTGACGACAA
TGGCGATGGAGTTCGAGCAGAGAGAGATTGTTCCAGCTGTGATAACTCCGGTTTACCGACTCAAGCCCGAGACCATTCAT
AACCCCAATGTGGTTAAGACCTTATTGGCTATTGACGGCCGAGCACTTTATTTTTCTCGCTCGGCGATTCCGCATGTGCG
CGATGTGGACCCTTTGGATTGGCATCGCCATGCCACCTACTGGGGGCATGTGGGGATGTATGGCTTTCGAGGAGATGTGT
TGGCCTGCTGGTCAGGTATGCCGCCTTCGCCTTTGGAAGCTCTTGAACGTCTAGAGCAATTGCGATTGATTGAAGCTGGT
CATACGATTTCTACCTTTGCAGTTGAGGGGACATCCCTTTCAGTGGATACGGTTGAGCAGTTGGAAGAAGCAAGGGAATG
TGCCTTGAAATCTTGA

Upstream 100 bases:

>100_bases
GTGGACCATGGTTCCGCGAACAGCGCACGATGGGTGGTGCCTTGGCGGCTGAATGGTTTAGTGCTCGTGATGATGCGATG
AAGCTATGGGATTAATGCCG

Downstream 100 bases:

>100_bases
CATTGAAGTCAGGGTGAATGGCATTTATTGCTCTCTGCTCCAAGTTGCAGATGTTGACCATATTGATTCAATATTGACAT
TCGGCAATTGATTTTTGACT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MGVQRSVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPNAVVLCTDSDRLKEMAEDWGFSVLMTSASCNSGS
ERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQGDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIH
NPNVVKTLLAIDGRALYFSRSAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
HTISTFAVEGTSLSVDTVEQLEEARECALKS

Sequences:

>Translated_271_residues
MGVQRSVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPNAVVLCTDSDRLKEMAEDWGFSVLMTSASCNSGS
ERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQGDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIH
NPNVVKTLLAIDGRALYFSRSAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
HTISTFAVEGTSLSVDTVEQLEEARECALKS
>Mature_270_residues
GVQRSVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPNAVVLCTDSDRLKEMAEDWGFSVLMTSASCNSGSE
RIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQGDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIHN
PNVVKTLLAIDGRALYFSRSAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAGH
TISTFAVEGTSLSVDTVEQLEEARECALKS

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=269, Percent_Identity=35.6877323420074, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 29976; Mature: 29844

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVQRSVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPNAVVLCTDSDRLKE
CCCCCCCEEECCHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
MAEDWGFSVLMTSASCNSGSERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQ
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEC
GDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIHNPNVVKTLLAIDGRALYFSR
CCCCCCCHHHHHHHHHHHHHHHCCHHHHCHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEC
SAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
CCCCCCCCCCCCCHHHCCCEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCC
HTISTFAVEGTSLSVDTVEQLEEARECALKS
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVQRSVVAVPARLESSRLPNKVLADIGGMPMLQRVLERCSQAHGPNAVVLCTDSDRLKE
CCCCCCEEECCHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
MAEDWGFSVLMTSASCNSGSERIASVADHLVAMAWDEQADGWDQQQQQQRLAMTAVINVQ
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEC
GDQPFLDPAVVTTMAMEFEQREIVPAVITPVYRLKPETIHNPNVVKTLLAIDGRALYFSR
CCCCCCCHHHHHHHHHHHHHHHCCHHHHCHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEC
SAIPHVRDVDPLDWHRHATYWGHVGMYGFRGDVLACWSGMPPSPLEALERLEQLRLIEAG
CCCCCCCCCCCCCHHHCCCEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCC
HTISTFAVEGTSLSVDTVEQLEEARECALKS
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA