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The map label for this gene is yggV [C]

Identifier: 33864139

GI number: 33864139

Start: 1979230

End: 1979841

Strand: Direct

Name: yggV [C]

Synonym: PMT1872

Alternate gene names: 33864139

Gene position: 1979230-1979841 (Clockwise)

Preceding gene: 33864138

Following gene: 33864142

Centisome position: 82.1

GC content: 55.56

Gene sequence:

>612_bases
ATGAGCAGCAATGAATTGACAGAGCGGGTGCTGGTGATCGCTAGCGGCAATGCTGGCAAAATTCGCGAGTTCCGTCAGTT
GCTGGCTCACCTGCCGCTCAGCGTGCAAGCCCAACCCAAAGATCTTGCCGTGGAAGAAACAGGCCAGACCTTTGCAGAAA
ATGCACGCATCAAGGCCTTGACAGTTGCTCAAGCCACGGGGCAATGGGCCCTCGCAGACGACTCCGGACTCAGCGTAGAG
GCACTGGCAGGCGCCCCTGGGGTGTATTCAGCCCGCTATGCCGCGAGTGATGCCCTAAGGATTGAGCGCCTACTACAAGA
ACTCAAAGGGATCGATGATCGCCGCGCTCACTTCAGCGCTGCTCTTTGCATCGCATCTGAGACGAATGAAGTTTTACTGG
AGGTCGAAGGCCGCTGCGAAGGTTTAATCACCCACGCAGCTCGAGGAGAAAAGGGCTTCGGCTATGACCCGATCTTCGAA
GTCGACGCAACCGGCACAACCTTTGCAGAGATGACTATTGAGCAAAAACGCCAATGGAGCCACAGAGGTTGCGCCTTTGC
CCTGTTAGATCCAGCCCTGCAAGAACTGCTCCACAAACAAAACAAGCCCTAA

Upstream 100 bases:

>100_bases
TCTCCGGCACCGAACCCCTGCTCAGGATCTACTGCGAAGCTCCCAGCGAGACAGACGTCAAAGCAGCTCTGAACTGGGCA
AAGCAGCTCGCAGAACGAAC

Downstream 100 bases:

>100_bases
ACGCGAGACCACCGAATCGCTAAACAATCAATCCACTCTCAACTAAGGAATTGAGCAGATCGCTTGATGGTGTTGATCTG
AAGCAAGGCAGCCAAAATGA

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSSNELTERVLVIASGNAGKIREFRQLLAHLPLSVQAQPKDLAVEETGQTFAENARIKALTVAQATGQWALADDSGLSVE
ALAGAPGVYSARYAASDALRIERLLQELKGIDDRRAHFSAALCIASETNEVLLEVEGRCEGLITHAARGEKGFGYDPIFE
VDATGTTFAEMTIEQKRQWSHRGCAFALLDPALQELLHKQNKP

Sequences:

>Translated_203_residues
MSSNELTERVLVIASGNAGKIREFRQLLAHLPLSVQAQPKDLAVEETGQTFAENARIKALTVAQATGQWALADDSGLSVE
ALAGAPGVYSARYAASDALRIERLLQELKGIDDRRAHFSAALCIASETNEVLLEVEGRCEGLITHAARGEKGFGYDPIFE
VDATGTTFAEMTIEQKRQWSHRGCAFALLDPALQELLHKQNKP
>Mature_202_residues
SSNELTERVLVIASGNAGKIREFRQLLAHLPLSVQAQPKDLAVEETGQTFAENARIKALTVAQATGQWALADDSGLSVEA
LAGAPGVYSARYAASDALRIERLLQELKGIDDRRAHFSAALCIASETNEVLLEVEGRCEGLITHAARGEKGFGYDPIFEV
DATGTTFAEMTIEQKRQWSHRGCAFALLDPALQELLHKQNKP

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=182, Percent_Identity=32.967032967033, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=45.5958549222798, Blast_Score=140, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17556833, Length=192, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322529, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_PROMM (Q7V4S3)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895699.1
- ProteinModelPortal:   Q7V4S3
- SMR:   Q7V4S3
- STRING:   Q7V4S3
- GeneID:   1728832
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1872
- NMPDR:   fig|74547.1.peg.1866
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- ProtClustDB:   PRK00120
- BioCyc:   PMAR74547:PMT1872-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 22059; Mature: 21928

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNELTERVLVIASGNAGKIREFRQLLAHLPLSVQAQPKDLAVEETGQTFAENARIKAL
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHCCHHHHHCCEEEEE
TVAQATGQWALADDSGLSVEALAGAPGVYSARYAASDALRIERLLQELKGIDDRRAHFSA
EEEECCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHE
ALCIASETNEVLLEVEGRCEGLITHAARGEKGFGYDPIFEVDATGTTFAEMTIEQKRQWS
EEEEECCCCEEEEEECCCCCEEEHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
HRGCAFALLDPALQELLHKQNKP
HCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSNELTERVLVIASGNAGKIREFRQLLAHLPLSVQAQPKDLAVEETGQTFAENARIKAL
CCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHCCHHHHHCCEEEEE
TVAQATGQWALADDSGLSVEALAGAPGVYSARYAASDALRIERLLQELKGIDDRRAHFSA
EEEECCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHE
ALCIASETNEVLLEVEGRCEGLITHAARGEKGFGYDPIFEVDATGTTFAEMTIEQKRQWS
EEEEECCCCEEEEEECCCCCEEEHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
HRGCAFALLDPALQELLHKQNKP
HCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642