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The map label for this gene is glmM [H]

Identifier: 33864138

GI number: 33864138

Start: 1977770

End: 1979233

Strand: Direct

Name: glmM [H]

Synonym: PMT1871

Alternate gene names: 33864138

Gene position: 1977770-1979233 (Clockwise)

Preceding gene: 33864136

Following gene: 33864139

Centisome position: 82.04

GC content: 58.61

Gene sequence:

>1464_bases
ATGGCATCGGCCCCCCTGCCGCTGGCCGCGGCCCCCATCCACTTCGGTACCGACGGTTGGCGCGGGGTCATCGGCGTAGA
TATCACAGTCGAAAGGTTGTTAACCGTTGCTGCTGCTGCTGCACAGGAGCTGGCCTATCGCGCACCCACAGAACTCAAAA
GCCGCTCAGTGATCATCGGCTACGACCGCCGCTTTCTAGCTCCGGAAATGGCAGAGGCCATTGCTGCCGCCGTGCGCGGC
TGTGAGCTGGAGCCCTTACTCACCGAAACGCCTGTGCCGACACCTGCCTGCAGCTGGGCAGTCGTTCAACATCAGGCCAT
TGGCGCCTTAGTGGTGACAGCCAGTCACAATCCGCCGGAATGGTTAGGGCTAAAAATCAAGGGGGCCTTTGGCGGCTCAG
TGGAAGACACTTTCACCGCAGCGGTGGAACAGCGACTTGCTGCCGGAGGGATCTCAGTACCCATCAATGGGATTACCAAG
CGATTTGATGGGCGTGGACAGCATCTCAAAGGATTGCGAGAGAAGCTCGATTTAACGTCTCTGATCAAGGGCCTGCAGAA
GATGGGGCTCAAGGTCATCATCGATCCGATGCACGGTTCAGCAGCGGGTTGCATTGCCGAGCTACTGGACCCGCACAACC
AGGGCTTGGTTCAAGAAATTCGCGCCCAGCGCGACCCGTTGTTCGGCGGCAACCCGCCCGAACCCCTCGCCCCATATCTG
AGCCAGCTGATCGCAGCTGTGCAGGCCTCCAGCGCTACCGGACAACCCGCCGTGGGTCTTGTGTTCGATGGCGATGGCGA
CCGCATTGCAGCCATAGATGAAGCTGGCAACTTCTGCAGCACCCAGCTGCTGATGCCCCTCCTGATTGACCACCTCGCCC
GAGCCAAACAACTGCCAGGCAAGGTTGTAAAAACCGTGAGTGGCTCTGACCTGATGCGTCTAGTTGCTGAGGATCTAGGC
CGGGAGGTGCTGGAACTACCGGTTGGTTTCAAATACATCGCCGCTGAAATGCTCAGCGGCGATGTGCTGGTGGGAGGTGA
GGAATCAGGAGGGGTGGGCTTCGGAATGCACCTACCTGAAAGGGATGCCCTCTTTGCAGCCCTGCTTGTACTGGAAGCAC
TTGTGGAGGGAGGGCAGCCCCTCGGCGCACGCATGAAAGCCCTGCAAGAGCGTTGTAGGGGGAGCAGTTTTTACGAACGC
TTCGATCTACGCCTTGCTGACATGGACTCGCGACAACGACTAGAAACTCTGCTTGAGCAAACCCCTCCAGCCACAGTTGC
TGATCAACCCGTTCAGACCGTGATCCGTACAGATGGCGTGAAATTTCGACTTGGACCTAGCCACTGGTTGATGCTGCGTT
TCTCCGGCACCGAACCCCTGCTCAGGATCTACTGCGAAGCTCCCAGCGAGACAGACGTCAAAGCAGCTCTGAACTGGGCA
AAGCAGCTCGCAGAACGAACATGA

Upstream 100 bases:

>100_bases
AGCAAGCGATCAGTCAGAACGTTGGCAGCGAGAGGGGTGGCACCCATCAGCCGACGTTACGGTGGCTGCCTGCTAGATCC
AGTCCATTAGTTGATCATTT

Downstream 100 bases:

>100_bases
GCAGCAATGAATTGACAGAGCGGGTGCTGGTGATCGCTAGCGGCAATGCTGGCAAAATTCGCGAGTTCCGTCAGTTGCTG
GCTCACCTGCCGCTCAGCGT

Product: phosphotransferase superclass

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MASAPLPLAAAPIHFGTDGWRGVIGVDITVERLLTVAAAAAQELAYRAPTELKSRSVIIGYDRRFLAPEMAEAIAAAVRG
CELEPLLTETPVPTPACSWAVVQHQAIGALVVTASHNPPEWLGLKIKGAFGGSVEDTFTAAVEQRLAAGGISVPINGITK
RFDGRGQHLKGLREKLDLTSLIKGLQKMGLKVIIDPMHGSAAGCIAELLDPHNQGLVQEIRAQRDPLFGGNPPEPLAPYL
SQLIAAVQASSATGQPAVGLVFDGDGDRIAAIDEAGNFCSTQLLMPLLIDHLARAKQLPGKVVKTVSGSDLMRLVAEDLG
REVLELPVGFKYIAAEMLSGDVLVGGEESGGVGFGMHLPERDALFAALLVLEALVEGGQPLGARMKALQERCRGSSFYER
FDLRLADMDSRQRLETLLEQTPPATVADQPVQTVIRTDGVKFRLGPSHWLMLRFSGTEPLLRIYCEAPSETDVKAALNWA
KQLAERT

Sequences:

>Translated_487_residues
MASAPLPLAAAPIHFGTDGWRGVIGVDITVERLLTVAAAAAQELAYRAPTELKSRSVIIGYDRRFLAPEMAEAIAAAVRG
CELEPLLTETPVPTPACSWAVVQHQAIGALVVTASHNPPEWLGLKIKGAFGGSVEDTFTAAVEQRLAAGGISVPINGITK
RFDGRGQHLKGLREKLDLTSLIKGLQKMGLKVIIDPMHGSAAGCIAELLDPHNQGLVQEIRAQRDPLFGGNPPEPLAPYL
SQLIAAVQASSATGQPAVGLVFDGDGDRIAAIDEAGNFCSTQLLMPLLIDHLARAKQLPGKVVKTVSGSDLMRLVAEDLG
REVLELPVGFKYIAAEMLSGDVLVGGEESGGVGFGMHLPERDALFAALLVLEALVEGGQPLGARMKALQERCRGSSFYER
FDLRLADMDSRQRLETLLEQTPPATVADQPVQTVIRTDGVKFRLGPSHWLMLRFSGTEPLLRIYCEAPSETDVKAALNWA
KQLAERT
>Mature_486_residues
ASAPLPLAAAPIHFGTDGWRGVIGVDITVERLLTVAAAAAQELAYRAPTELKSRSVIIGYDRRFLAPEMAEAIAAAVRGC
ELEPLLTETPVPTPACSWAVVQHQAIGALVVTASHNPPEWLGLKIKGAFGGSVEDTFTAAVEQRLAAGGISVPINGITKR
FDGRGQHLKGLREKLDLTSLIKGLQKMGLKVIIDPMHGSAAGCIAELLDPHNQGLVQEIRAQRDPLFGGNPPEPLAPYLS
QLIAAVQASSATGQPAVGLVFDGDGDRIAAIDEAGNFCSTQLLMPLLIDHLARAKQLPGKVVKTVSGSDLMRLVAEDLGR
EVLELPVGFKYIAAEMLSGDVLVGGEESGGVGFGMHLPERDALFAALLVLEALVEGGQPLGARMKALQERCRGSSFYERF
DLRLADMDSRQRLETLLEQTPPATVADQPVQTVIRTDGVKFRLGPSHWLMLRFSGTEPLLRIYCEAPSETDVKAALNWAK
QLAERT

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=465, Percent_Identity=24.7311827956989, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI21361621, Length=411, Percent_Identity=24.5742092457421, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI133922562, Length=484, Percent_Identity=24.5867768595041, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789566, Length=477, Percent_Identity=25.5765199161426, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786904, Length=494, Percent_Identity=25.3036437246964, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17535441, Length=457, Percent_Identity=25.382932166302, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323752, Length=415, Percent_Identity=24.0963855421687, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17864244, Length=408, Percent_Identity=26.4705882352941, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 52069; Mature: 51938

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAPLPLAAAPIHFGTDGWRGVIGVDITVERLLTVAAAAAQELAYRAPTELKSRSVIIG
CCCCCCCCEECCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEE
YDRRFLAPEMAEAIAAAVRGCELEPLLTETPVPTPACSWAVVQHQAIGALVVTASHNPPE
CCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCC
WLGLKIKGAFGGSVEDTFTAAVEQRLAAGGISVPINGITKRFDGRGQHLKGLREKLDLTS
EEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
LIKGLQKMGLKVIIDPMHGSAAGCIAELLDPHNQGLVQEIRAQRDPLFGGNPPEPLAPYL
HHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
SQLIAAVQASSATGQPAVGLVFDGDGDRIAAIDEAGNFCSTQLLMPLLIDHLARAKQLPG
HHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
KVVKTVSGSDLMRLVAEDLGREVLELPVGFKYIAAEMLSGDVLVGGEESGGVGFGMHLPE
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCEEEECCCCC
RDALFAALLVLEALVEGGQPLGARMKALQERCRGSSFYERFDLRLADMDSRQRLETLLEQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCEEECCCHHHHHHHHHHC
TPPATVADQPVQTVIRTDGVKFRLGPSHWLMLRFSGTEPLLRIYCEAPSETDVKAALNWA
CCCCCCCCCHHHHHHHCCCEEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHH
KQLAERT
HHHHHCC
>Mature Secondary Structure 
ASAPLPLAAAPIHFGTDGWRGVIGVDITVERLLTVAAAAAQELAYRAPTELKSRSVIIG
CCCCCCCEECCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEE
YDRRFLAPEMAEAIAAAVRGCELEPLLTETPVPTPACSWAVVQHQAIGALVVTASHNPPE
CCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCC
WLGLKIKGAFGGSVEDTFTAAVEQRLAAGGISVPINGITKRFDGRGQHLKGLREKLDLTS
EEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
LIKGLQKMGLKVIIDPMHGSAAGCIAELLDPHNQGLVQEIRAQRDPLFGGNPPEPLAPYL
HHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
SQLIAAVQASSATGQPAVGLVFDGDGDRIAAIDEAGNFCSTQLLMPLLIDHLARAKQLPG
HHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
KVVKTVSGSDLMRLVAEDLGREVLELPVGFKYIAAEMLSGDVLVGGEESGGVGFGMHLPE
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCEEEECCCCC
RDALFAALLVLEALVEGGQPLGARMKALQERCRGSSFYERFDLRLADMDSRQRLETLLEQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCEEECCCHHHHHHHHHHC
TPPATVADQPVQTVIRTDGVKFRLGPSHWLMLRFSGTEPLLRIYCEAPSETDVKAALNWA
CCCCCCCCCHHHHHHHCCCEEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHH
KQLAERT
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA