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The map label for this gene is cinA [C]

Identifier: 33864112

GI number: 33864112

Start: 1952777

End: 1954066

Strand: Reverse

Name: cinA [C]

Synonym: PMT1845

Alternate gene names: 33864112

Gene position: 1954066-1952777 (Counterclockwise)

Preceding gene: 33864113

Following gene: 33864111

Centisome position: 81.05

GC content: 56.28

Gene sequence:

>1290_bases
GTGCCTATCGCGATGGTCATGGCTGAAGCTTCGGCTAGGCATGGTGTTGAGATCCTTTGCATTGGCACGGAGCTGTTGCT
TGGCAACATCCTTAACAGCAATGCACGTTGGTTAGCTGAGGAGCTGGCTGCTCTGGGGCTCCCTCATTACCGCCAAACTG
TTGTAGGAGACAACGTTGAACGTCTCAAAGAATCAGTTTTGGAGGCTGTTGATCGCAGTCGGATTCTGATCACCACTGGT
GGCCTCGGACCAACGCCTGATGATCTGACTACTGAAACTTTGGCGGCTGCTTTTGATACGCCGCTTGAGGAACGTCCAGA
ACTTTGGTTCGAGATTCAGGCCAAGCTCACTGCTGGCGGCAGCATTTCTGCAATCAGCAATCGCAAACAGGCGTTGTTCC
CTCGTGGAGCTGAAATCCTTCCAAATCCTTCCGGTACTGCGCCGGGGATGATCTGGTGTCCTCGGCCGGGGTTCACTGTG
CTCACCTTTCCGGGTGTGCCTTCTGAAATGAAGCAGATGTGGTCCCAGACAGCCGTGCCATGGCTGCGTCAGCACGGAGG
ACTTGCTGACATCTTTGTGAGTCGGCTGTTGCGGTTTACAGGAATTGCTGAATCCACGCTTGCTGAAGAGGTGGCTGATT
TGCTTGAGCAGGGCAATCCAACAGTGGCCCCGTATGCCGGCCTGGGAGAGGTGAAACTACGGATCACGGCCCGAGGGGCA
ACGGTGGAGCAAGCCAGGCAGCTATTGGATCCAGTGGATGCAGCGCTCCGTCATCGCACCGGCTTGTTCTGTTACGGCTC
GGATGATGAGAGTTTGGCATCGGTTGTGCTGGATTTGTTGCGTCAACGAGGTGAGACCGTTGTAGTGGCAGAGTCTTGTA
CAGGTGGCGGCGTTGGTGCAGCTTTGGCTGCTGTTCCGAGAGCTTCTGAGGTTTTTCTTGGCGGGGTCATTGCTTACAGC
AATGCCATTAAGCAAGCCCTATTGGGTATATCCACAGACCTTTTGCATCAGCACGGTGCAGTTTCGGATCCTGTGGTGCG
GGCTATGGCTGAAGGGGCGCGTCAACGGCTGGGGGCAGATTGGTCCATTGCGGTGAGCGGTGTGGCAGGCCCTGGCGGTG
GTACGCACGCCAAGCCTGTGGGGTTAGTGCATATCGCAGTAGCGGGACCGCATGGCTGTGATGCAAGCCCTGTGCAGTTC
GGTGTTCGTCGTGGAAGGTTGGCAATTCAGGAGCTGAGTGTGGTTCGCAGTCTCGATCAGCTGCGCAGGCTCCTGCTGGA
TGGGAGCTAA

Upstream 100 bases:

>100_bases
GCCATTCTCGTGGCGACAGTCGTGATCAGCCGTCGTCAACGTAGTGCTGAAGGTGTTTTCGTAGACCCTTCTAGCCCCCT
TGCAGCTCCTAGTGATCCAC

Downstream 100 bases:

>100_bases
GGTTTTCGGCTACTGCCTCTGAACCTTGAGCTCCGGCACCCTCTACGACAAGGTGTGGGATCTCCATCGGGTGGCTGACC
TGCCTGGTGGATCCACTCAG

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MPIAMVMAEASARHGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVERLKESVLEAVDRSRILITTG
GLGPTPDDLTTETLAAAFDTPLEERPELWFEIQAKLTAGGSISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTV
LTFPGVPSEMKQMWSQTAVPWLRQHGGLADIFVSRLLRFTGIAESTLAEEVADLLEQGNPTVAPYAGLGEVKLRITARGA
TVEQARQLLDPVDAALRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGAALAAVPRASEVFLGGVIAYS
NAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGADWSIAVSGVAGPGGGTHAKPVGLVHIAVAGPHGCDASPVQF
GVRRGRLAIQELSVVRSLDQLRRLLLDGS

Sequences:

>Translated_429_residues
MPIAMVMAEASARHGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVERLKESVLEAVDRSRILITTG
GLGPTPDDLTTETLAAAFDTPLEERPELWFEIQAKLTAGGSISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTV
LTFPGVPSEMKQMWSQTAVPWLRQHGGLADIFVSRLLRFTGIAESTLAEEVADLLEQGNPTVAPYAGLGEVKLRITARGA
TVEQARQLLDPVDAALRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGAALAAVPRASEVFLGGVIAYS
NAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGADWSIAVSGVAGPGGGTHAKPVGLVHIAVAGPHGCDASPVQF
GVRRGRLAIQELSVVRSLDQLRRLLLDGS
>Mature_428_residues
PIAMVMAEASARHGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVERLKESVLEAVDRSRILITTGG
LGPTPDDLTTETLAAAFDTPLEERPELWFEIQAKLTAGGSISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTVL
TFPGVPSEMKQMWSQTAVPWLRQHGGLADIFVSRLLRFTGIAESTLAEEVADLLEQGNPTVAPYAGLGEVKLRITARGAT
VEQARQLLDPVDAALRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGAALAAVPRASEVFLGGVIAYSN
AIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGADWSIAVSGVAGPGGGTHAKPVGLVHIAVAGPHGCDASPVQFG
VRRGRLAIQELSVVRSLDQLRRLLLDGS

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=411, Percent_Identity=29.683698296837, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789052, Length=121, Percent_Identity=44.6280991735537, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787818, Length=112, Percent_Identity=36.6071428571429, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_PROMM (Q7TUN0)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895672.1
- ProteinModelPortal:   Q7TUN0
- SMR:   Q7TUN0
- STRING:   Q7TUN0
- GeneID:   1728487
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1845
- NMPDR:   fig|74547.1.peg.1839
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK826228
- BioCyc:   PMAR74547:PMT1845-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45303; Mature: 45171

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAMVMAEASARHGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVE
CCCEEEEEHHHCCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHH
RLKESVLEAVDRSRILITTGGLGPTPDDLTTETLAAAFDTPLEERPELWFEIQAKLTAGG
HHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCC
SISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTVLTFPGVPSEMKQMWSQTAVP
CCHHHCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCH
WLRQHGGLADIFVSRLLRFTGIAESTLAEEVADLLEQGNPTVAPYAGLGEVKLRITARGA
HHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
TVEQARQLLDPVDAALRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGA
CHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALAAVPRASEVFLGGVIAYSNAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGAD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
WSIAVSGVAGPGGGTHAKPVGLVHIAVAGPHGCDASPVQFGVRRGRLAIQELSVVRSLDQ
CEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRLLLDGS
HHHHHCCCC
>Mature Secondary Structure 
PIAMVMAEASARHGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVE
CCEEEEEHHHCCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHH
RLKESVLEAVDRSRILITTGGLGPTPDDLTTETLAAAFDTPLEERPELWFEIQAKLTAGG
HHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCC
SISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTVLTFPGVPSEMKQMWSQTAVP
CCHHHCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCH
WLRQHGGLADIFVSRLLRFTGIAESTLAEEVADLLEQGNPTVAPYAGLGEVKLRITARGA
HHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
TVEQARQLLDPVDAALRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGA
CHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALAAVPRASEVFLGGVIAYSNAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGAD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
WSIAVSGVAGPGGGTHAKPVGLVHIAVAGPHGCDASPVQFGVRRGRLAIQELSVVRSLDQ
CEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRLLLDGS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642