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The map label for this gene is pgm [H]

Identifier: 33863881

GI number: 33863881

Start: 1712999

End: 1714699

Strand: Direct

Name: pgm [H]

Synonym: PMT1614

Alternate gene names: 33863881

Gene position: 1712999-1714699 (Clockwise)

Preceding gene: 33863879

Following gene: 33863885

Centisome position: 71.05

GC content: 54.85

Gene sequence:

>1701_bases
TTGCGTTTGATTAGGTTCGATGAAGAACTGCCTTCGTCTCTGATGACCAGCTCGGCCCAGACGGGACCCACACAGCGCCA
GGTACATCTGAACACACCCTTCAACGACCAAAAGCCAGGGACCTCCGGCCTACGCAAAAGCAGCAAGCAATTCGAACAAA
CCAATTACCTGGAGAGCTTCATTGAAGCAATCTTCCAAACCCTACCTGGCGTTGAGGGAGGGACTCTGATCTTGGGGGGG
GATGGTCGCTACGGCAATCACCGCGCCATTGATGTGATCCTGCGTATGGGTGCTGCTCATGGCCTAAGCCGAGTGATCAC
CACCACAAATGGCATTCTCTCCACGCCGGCAGCATCCCATCTCATCCGTGCCAATAAGGCCATCGGAGGAATCATCCTTT
CCGCGAGCCACAACCAAGGCGGTCCAGATGGCGACTTCGGCGTCAAAGTCAACGGTGCCAATGGTGGCCCAGCAGCCGAA
TCACTCACAAACGCGATCTACGCATGTAGCCAAGCTTTAGAGAAATACAGCCTTGTCGATGCAGACGTAATCCCACTTGA
AACCCCCGGCCACCATGCCATCGGTGGCATGACCGTAGACGTGATCGACGGCGTTGAAGACTATGTAGAGCTGATGCAGA
AGTTGTTCGACTTCGGGCGCATCAAGGACCTCATCAAAACCGACTTCCCAGTCGTGTTTGATGCCATGCATGCTGTCACT
GGTCCCTATGCAAAACGGCTACTGGAAGGACTTCTCGGTGCCCCAACTGGCACTGTGCGCAACGGAGTCCCGCTTGAGGA
TTTTGGTGGAGGCCACCCAGATCCCAACCTCACCTACGCCGCTGAACTAGCAGACCTCCTCCTCAATGGCAAGGCCTACA
GCTTCGGTGCCGCCTGCGATGGTGATGGCGACCGCAACATGATCCTGGGCAGAGGTTGCTTCGTTAACCCAAGTGACAGC
CTTGCAATCCTGGCTGCTAATGCCAACGTTGCACCGGCCTATGCCGATGGGCTTGCTGGTGTGGCCCGCTCCATGCCCAC
TAGCGCCGCAGTGGATGTTGTAGCCAAACAACTCAATATCGACTGTTTTGAAACTCCCACCGGGTGGAAGTTTTTCGGCA
ACCTGCTTGATGCAGGTCGAATCACCCTCTGTGGTGAAGAAAGCTTCGGCACTGGCAGCAACCACGTGCGTGAGAAGGAT
GGACTATGGGCAGTGCTCTTCTGGCTACAGATCCTGGCAGAGCGACGCTGCAGCGTCGCTGATGTGATGACACAGCATTG
GAGTCGTTTTGGACGCCATTACTACTCCCGTCACGACTACGAGGCGATTGCTAGTGAAAATGCTCATGGTCTTTACAACC
GGTTGGAGAGCATGCTTCCTCGACTAATCGGTCAACCATTCGCCGGGCGCCAAGTGAGCCAGGCAGACAATTTTAGTTAT
AGCGATCCTGTGGATGGCTCAGAGACACAATCTCAGGGTCTACGCATCCTGCTGGAAGACGGCAGCAGAGTCGTGGTTCG
ACTCTCGGGCACCGGCACCAAAGGTGCCACATTGCGCGTTTATCTAGAATGCTACGAACCTAGTCATGGCAACTTAAATC
AAGATCCCCAGCATGCTCTAGCCGATCTCATCAATGGCATCGATGCGCTTGCCGAAATTCAAAAGCGCACTGGGATGCAA
CGACCAACGGTGATCACTTGA

Upstream 100 bases:

>100_bases
CCGCCCATTCCCCAACAACTGAGCTGCACCTCAGATCCTCTCAATGATCTTTGCGAACACTAGCCGCGAGAACTGGAGGG
GGCCAAAACAGGATCGATGA

Downstream 100 bases:

>100_bases
TCTCAGCGCAGCCACCACTCCCGTGGGCGGCGGTGATACTCCGCCTCGGTGCTGCTTTGTTGCAGCTGGCGCATGCTTTC
AATGACCACTGCTCCAAGCG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MRLIRFDEELPSSLMTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGGTLILGG
DGRYGNHRAIDVILRMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAE
SLTNAIYACSQALEKYSLVDADVIPLETPGHHAIGGMTVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVT
GPYAKRLLEGLLGAPTGTVRNGVPLEDFGGGHPDPNLTYAAELADLLLNGKAYSFGAACDGDGDRNMILGRGCFVNPSDS
LAILAANANVAPAYADGLAGVARSMPTSAAVDVVAKQLNIDCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKD
GLWAVLFWLQILAERRCSVADVMTQHWSRFGRHYYSRHDYEAIASENAHGLYNRLESMLPRLIGQPFAGRQVSQADNFSY
SDPVDGSETQSQGLRILLEDGSRVVVRLSGTGTKGATLRVYLECYEPSHGNLNQDPQHALADLINGIDALAEIQKRTGMQ
RPTVIT

Sequences:

>Translated_566_residues
MRLIRFDEELPSSLMTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGGTLILGG
DGRYGNHRAIDVILRMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAE
SLTNAIYACSQALEKYSLVDADVIPLETPGHHAIGGMTVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVT
GPYAKRLLEGLLGAPTGTVRNGVPLEDFGGGHPDPNLTYAAELADLLLNGKAYSFGAACDGDGDRNMILGRGCFVNPSDS
LAILAANANVAPAYADGLAGVARSMPTSAAVDVVAKQLNIDCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKD
GLWAVLFWLQILAERRCSVADVMTQHWSRFGRHYYSRHDYEAIASENAHGLYNRLESMLPRLIGQPFAGRQVSQADNFSY
SDPVDGSETQSQGLRILLEDGSRVVVRLSGTGTKGATLRVYLECYEPSHGNLNQDPQHALADLINGIDALAEIQKRTGMQ
RPTVIT
>Mature_566_residues
MRLIRFDEELPSSLMTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGGTLILGG
DGRYGNHRAIDVILRMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAE
SLTNAIYACSQALEKYSLVDADVIPLETPGHHAIGGMTVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVT
GPYAKRLLEGLLGAPTGTVRNGVPLEDFGGGHPDPNLTYAAELADLLLNGKAYSFGAACDGDGDRNMILGRGCFVNPSDS
LAILAANANVAPAYADGLAGVARSMPTSAAVDVVAKQLNIDCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKD
GLWAVLFWLQILAERRCSVADVMTQHWSRFGRHYYSRHDYEAIASENAHGLYNRLESMLPRLIGQPFAGRQVSQADNFSY
SDPVDGSETQSQGLRILLEDGSRVVVRLSGTGTKGATLRVYLECYEPSHGNLNQDPQHALADLINGIDALAEIQKRTGMQ
RPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=569, Percent_Identity=50.4393673110721, Blast_Score=571, Evalue=1e-163,
Organism=Homo sapiens, GI21361621, Length=552, Percent_Identity=50.7246376811594, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI133922562, Length=556, Percent_Identity=47.6618705035971, Blast_Score=503, Evalue=1e-142,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=53.0054644808743, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI239741729, Length=123, Percent_Identity=45.5284552845528, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI239743670, Length=114, Percent_Identity=46.4912280701754, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1786904, Length=425, Percent_Identity=27.2941176470588, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17535441, Length=559, Percent_Identity=49.3738819320215, Blast_Score=521, Evalue=1e-148,
Organism=Saccharomyces cerevisiae, GI6323752, Length=578, Percent_Identity=43.7716262975779, Blast_Score=472, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6322722, Length=560, Percent_Identity=44.1071428571429, Blast_Score=452, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17864244, Length=558, Percent_Identity=47.6702508960573, Blast_Score=520, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 60776; Mature: 60776

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIRFDEELPSSLMTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESF
CCEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IEAIFQTLPGVEGGTLILGGDGRYGNHRAIDVILRMGAAHGLSRVITTTNGILSTPAASH
HHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALEKYSLVD
HHHHHHCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
ADVIPLETPGHHAIGGMTVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVT
CCEEECCCCCCCCCCCEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GPYAKRLLEGLLGAPTGTVRNGVPLEDFGGGHPDPNLTYAAELADLLLNGKAYSFGAACD
CHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCC
GDGDRNMILGRGCFVNPSDSLAILAANANVAPAYADGLAGVARSMPTSAAVDVVAKQLNI
CCCCCCEEEECCCEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
DCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAERRCSVA
EEEECCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCHHH
DVMTQHWSRFGRHYYSRHDYEAIASENAHGLYNRLESMLPRLIGQPFAGRQVSQADNFSY
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SDPVDGSETQSQGLRILLEDGSRVVVRLSGTGTKGATLRVYLECYEPSHGNLNQDPQHAL
CCCCCCCCCHHCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHH
ADLINGIDALAEIQKRTGMQRPTVIT
HHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRLIRFDEELPSSLMTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESF
CCEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IEAIFQTLPGVEGGTLILGGDGRYGNHRAIDVILRMGAAHGLSRVITTTNGILSTPAASH
HHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALEKYSLVD
HHHHHHCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
ADVIPLETPGHHAIGGMTVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVT
CCEEECCCCCCCCCCCEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GPYAKRLLEGLLGAPTGTVRNGVPLEDFGGGHPDPNLTYAAELADLLLNGKAYSFGAACD
CHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCC
GDGDRNMILGRGCFVNPSDSLAILAANANVAPAYADGLAGVARSMPTSAAVDVVAKQLNI
CCCCCCEEEECCCEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
DCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAERRCSVA
EEEECCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCHHH
DVMTQHWSRFGRHYYSRHDYEAIASENAHGLYNRLESMLPRLIGQPFAGRQVSQADNFSY
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SDPVDGSETQSQGLRILLEDGSRVVVRLSGTGTKGATLRVYLECYEPSHGNLNQDPQHAL
CCCCCCCCCHHCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHH
ADLINGIDALAEIQKRTGMQRPTVIT
HHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]