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The map label for this gene is fabZ

Identifier: 33863678

GI number: 33863678

Start: 1497433

End: 1497861

Strand: Reverse

Name: fabZ

Synonym: PMT1411

Alternate gene names: 33863678

Gene position: 1497861-1497433 (Counterclockwise)

Preceding gene: 33863679

Following gene: 33863677

Centisome position: 62.13

GC content: 54.78

Gene sequence:

>429_bases
GTGTTGACAAGTGAGCAGATCATGGGGCTGCTGCCTCATCGTTATCCGTTTGCTCTGGTTGATCGTGTTGTGCTCCATGA
ACCTGGCCAGCGGGCTGTTGCGATCAAAAATGTGACCCTCAATGAACCTCAGTTTCAGGGTCATTTCCCTGGTCGTCCTT
TGATGCCTGGGGTCTTGATTGTTGAGGCGATGGCCCAGGTGGGTGGTTTGATCGTGGCCCAGATGCCAGATCTGCCCAAG
GGGTTATTCGTGTTTGCAGGTATCGATGCAGTTCGTTTCCGCCGTCCGGTGGTGCCAGGAGATCAGCTCACGATTAGCTG
TGAACTGCTTAGCTTGAAGCGGCAGCGCTTTGGCAAGGTCAGGGGTGAAGCCAGGGTGGAGGGCCAGCTGGTTTGCTCTG
GTGAGTTGATGTTTTCCTTGGTGGACTGA

Upstream 100 bases:

>100_bases
TCTATCGGGGGTCCCATGGACTCCATAACGATCTGGCCAATGCTCTCCTTGCCGTCTGTCCTGTCACTGTCTCTTGACCG
ATCCCTCTCCTAATCCTGTT

Downstream 100 bases:

>100_bases
GGATCATGAGCGAGGTGAGCAAACTCTCAGCGATCACTGCAGAAAAAAAGGCTCAGGTTCACCCTGCGGCTGTGGTGGAT
CCTCGTGCTGAGCTCGCTTC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLTSEQIMGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVAQMPDLPK
GLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVEGQLVCSGELMFSLVD

Sequences:

>Translated_142_residues
MLTSEQIMGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVAQMPDLPK
GLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVEGQLVCSGELMFSLVD
>Mature_142_residues
MLTSEQIMGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVAQMPDLPK
GLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKVRGEARVEGQLVCSGELMFSLVD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=49.2753623188406, Blast_Score=132, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PROMM (Q7V5X4)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895238.1
- ProteinModelPortal:   Q7V5X4
- SMR:   Q7V5X4
- STRING:   Q7V5X4
- GeneID:   1727912
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1411
- NMPDR:   fig|74547.1.peg.1405
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   PMAR74547:PMT1411-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15631; Mature: 15631

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSEQIMGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHH
VEAMAQVGGLIVAQMPDLPKGLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKV
HHHHHHHCCEEEEECCCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCC
RGEARVEGQLVCSGELMFSLVD
CCCEEECEEEEECCCEEEEECC
>Mature Secondary Structure
MLTSEQIMGLLPHRYPFALVDRVVLHEPGQRAVAIKNVTLNEPQFQGHFPGRPLMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHH
VEAMAQVGGLIVAQMPDLPKGLFVFAGIDAVRFRRPVVPGDQLTISCELLSLKRQRFGKV
HHHHHHHCCEEEEECCCCCCCEEEEECCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCC
RGEARVEGQLVCSGELMFSLVD
CCCEEECEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642