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The map label for this gene is degQ [C]

Identifier: 33863458

GI number: 33863458

Start: 1278762

End: 1279916

Strand: Direct

Name: degQ [C]

Synonym: PMT1188

Alternate gene names: 33863458

Gene position: 1278762-1279916 (Clockwise)

Preceding gene: 33863455

Following gene: 33863459

Centisome position: 53.04

GC content: 55.24

Gene sequence:

>1155_bases
ATGACCCTTGCCCTATCTGCCCACAGGCTGCATCCGCTCAGATGGCTTGGCTTGATCCTCATCAGCATCAACCTAAGTGG
CTGCAACGAAGGGTTACGTCAACGCATCGGCATTGGTTCTAAGACAAGTCCAGACAACACCCCTGTCGTCAGTGATCCAC
CCAAGTCAGCGCCTCTGCAGCCTGGCACCAATGTGATCGTGATTGCGGTGGAACAAGTTGGTCCGGCAGTGGTGCGCATC
GACACGGTGAAACGGATCGCAAACCCCCTTGGCAACTTTTTCGGCGGCGGACCTCCCATCCAACGGCAAGCCGGCCAAGG
GTCAGGTTTCATCACACGCTCTGACGGGCTGATCTTCACCAATGCTCATGTGGTTGATGGGGCAGAACGGGTATCAGTAA
CCCTTCCAGATGGACGCAGTTACAGCGGCAAAGTGCTTGGTGGTGATCCCCTTACAGATGTAGCCGTGGTCAAAGTCGTA
GCGAAGAAACTTCCAGTAGCCCCACTCGGCAATTCCAACAACATCAAGCCTGGGCAATGGGCAATCGCGATCGGCAATCC
TCTTGGACTCAACAACACCGTTACTGCAGGCATCATCAGCTCCGTCGACCGCACCAACGCCTTAGGGGGGGGGCAACGAG
TTCCTTACATCCAAACGGACGCCGCCGTAAACCCTGGCAATAGCGGAGGACCACTCATCAATGCCTCAGGACAGGTGATC
GGAATCAATACTGCCATCAAAGTTGCGCCGGGAGGCGGGCTGAGTTTTGCAGTACCGATCAACCTGGCCAAACGAATTGC
CCAACAAATCGTGGGGAGAGGGCAAGCTTCTCATCCCTATATCGGGGTAAGGCTGCAGAGCCTTACCCCCCAACTAGCCA
AAGAAATCAACGCAACAGGAGGGGCATGCCAAGTACCTGAAGTTAATGCTGTTCTCGTTGTTGAAGTGATGTCTCGCAGC
CCTGCAGACAAAGCCGGCGTGCGCCAATGCGACTTAATTCGTGAAGTCAATGGTGAGGTCGTCCGCGACCCTTCACAAGT
ACAACTTGCCGTTGATCGTGGGGAGGTTGGCAAGCCCATGCCGCTCACCCTTGAACGAAACAACAAGACGATCGAATTAA
TCGTCAAACCAGCAGAGCTACCCCGGCAGGGGTGA

Upstream 100 bases:

>100_bases
CATCCTTTCCTCTGCGATGGCTGAATCTACGCAACTTCTATCGAGCAAGCCGTCTTTAATAAGACCCTGATGTTCTCGTT
CCCTGGCACCTGCGTTTGTC

Downstream 100 bases:

>100_bases
ATTGAAATGGCAAAACCTGCACTGGTGGTGATGGCCCGCTGGCCGGCAGCAGGCAGATGCAAACGAAGACTGGCCGACAC
TCTTGGAATAGTGCGTGCAG

Product: serine protease trypsin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTLALSAHRLHPLRWLGLILISINLSGCNEGLRQRIGIGSKTSPDNTPVVSDPPKSAPLQPGTNVIVIAVEQVGPAVVRI
DTVKRIANPLGNFFGGGPPIQRQAGQGSGFITRSDGLIFTNAHVVDGAERVSVTLPDGRSYSGKVLGGDPLTDVAVVKVV
AKKLPVAPLGNSNNIKPGQWAIAIGNPLGLNNTVTAGIISSVDRTNALGGGQRVPYIQTDAAVNPGNSGGPLINASGQVI
GINTAIKVAPGGGLSFAVPINLAKRIAQQIVGRGQASHPYIGVRLQSLTPQLAKEINATGGACQVPEVNAVLVVEVMSRS
PADKAGVRQCDLIREVNGEVVRDPSQVQLAVDRGEVGKPMPLTLERNNKTIELIVKPAELPRQG

Sequences:

>Translated_384_residues
MTLALSAHRLHPLRWLGLILISINLSGCNEGLRQRIGIGSKTSPDNTPVVSDPPKSAPLQPGTNVIVIAVEQVGPAVVRI
DTVKRIANPLGNFFGGGPPIQRQAGQGSGFITRSDGLIFTNAHVVDGAERVSVTLPDGRSYSGKVLGGDPLTDVAVVKVV
AKKLPVAPLGNSNNIKPGQWAIAIGNPLGLNNTVTAGIISSVDRTNALGGGQRVPYIQTDAAVNPGNSGGPLINASGQVI
GINTAIKVAPGGGLSFAVPINLAKRIAQQIVGRGQASHPYIGVRLQSLTPQLAKEINATGGACQVPEVNAVLVVEVMSRS
PADKAGVRQCDLIREVNGEVVRDPSQVQLAVDRGEVGKPMPLTLERNNKTIELIVKPAELPRQG
>Mature_383_residues
TLALSAHRLHPLRWLGLILISINLSGCNEGLRQRIGIGSKTSPDNTPVVSDPPKSAPLQPGTNVIVIAVEQVGPAVVRID
TVKRIANPLGNFFGGGPPIQRQAGQGSGFITRSDGLIFTNAHVVDGAERVSVTLPDGRSYSGKVLGGDPLTDVAVVKVVA
KKLPVAPLGNSNNIKPGQWAIAIGNPLGLNNTVTAGIISSVDRTNALGGGQRVPYIQTDAAVNPGNSGGPLINASGQVIG
INTAIKVAPGGGLSFAVPINLAKRIAQQIVGRGQASHPYIGVRLQSLTPQLAKEINATGGACQVPEVNAVLVVEVMSRSP
ADKAGVRQCDLIREVNGEVVRDPSQVQLAVDRGEVGKPMPLTLERNNKTIELIVKPAELPRQG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=333, Percent_Identity=36.9369369369369, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI22129776, Length=326, Percent_Identity=38.3435582822086, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI7019477, Length=324, Percent_Identity=37.6543209876543, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI24308541, Length=306, Percent_Identity=35.2941176470588, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1789629, Length=321, Percent_Identity=35.202492211838, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786356, Length=271, Percent_Identity=37.6383763837638, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1789630, Length=281, Percent_Identity=34.5195729537367, Blast_Score=139, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24646839, Length=301, Percent_Identity=34.21926910299, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39884; Mature: 39752

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLALSAHRLHPLRWLGLILISINLSGCNEGLRQRIGIGSKTSPDNTPVVSDPPKSAPLQ
CEEEECHHHCCHHHEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PGTNVIVIAVEQVGPAVVRIDTVKRIANPLGNFFGGGPPIQRQAGQGSGFITRSDGLIFT
CCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEE
NAHVVDGAERVSVTLPDGRSYSGKVLGGDPLTDVAVVKVVAKKLPVAPLGNSNNIKPGQW
CCEEECCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
AIAIGNPLGLNNTVTAGIISSVDRTNALGGGQRVPYIQTDAAVNPGNSGGPLINASGQVI
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEECCCCEE
GINTAIKVAPGGGLSFAVPINLAKRIAQQIVGRGQASHPYIGVRLQSLTPQLAKEINATG
EECEEEEECCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCHHHHHHHCCCC
GACQVPEVNAVLVVEVMSRSPADKAGVRQCDLIREVNGEVVRDPSQVQLAVDRGEVGKPM
CEEECCCCCEEEEEEEECCCCCCHHCCHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCC
PLTLERNNKTIELIVKPAELPRQG
EEEEECCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
TLALSAHRLHPLRWLGLILISINLSGCNEGLRQRIGIGSKTSPDNTPVVSDPPKSAPLQ
EEEECHHHCCHHHEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PGTNVIVIAVEQVGPAVVRIDTVKRIANPLGNFFGGGPPIQRQAGQGSGFITRSDGLIFT
CCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEE
NAHVVDGAERVSVTLPDGRSYSGKVLGGDPLTDVAVVKVVAKKLPVAPLGNSNNIKPGQW
CCEEECCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
AIAIGNPLGLNNTVTAGIISSVDRTNALGGGQRVPYIQTDAAVNPGNSGGPLINASGQVI
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEECCCCEE
GINTAIKVAPGGGLSFAVPINLAKRIAQQIVGRGQASHPYIGVRLQSLTPQLAKEINATG
EECEEEEECCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCHHHHHHHCCCC
GACQVPEVNAVLVVEVMSRSPADKAGVRQCDLIREVNGEVVRDPSQVQLAVDRGEVGKPM
CEEECCCCCEEEEEEEECCCCCCHHCCHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCC
PLTLERNNKTIELIVKPAELPRQG
EEEEECCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA