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The map label for this gene is fur [H]

Identifier: 33863130

GI number: 33863130

Start: 939703

End: 940515

Strand: Direct

Name: fur [H]

Synonym: PMT0858

Alternate gene names: 33863130

Gene position: 939703-940515 (Clockwise)

Preceding gene: 33863129

Following gene: 33863133

Centisome position: 38.98

GC content: 50.06

Gene sequence:

>813_bases
GTGCCCAGCCAGCGGACAGGGAACAATCAACAGGCAGTGGCAAAAGTCATCAAGGGCCAAACAATCTGGCCTTACACCGA
CTTTTACTTCGCGGGATGGGGTCTAGCCTCTAATAAGTATCATCTTACATGCAGGCGAGGCTACAACAGCCTAGTAGCGC
TATCAGGCCTTGCCACAAAGGCAGAAGGATCAACTATTGGCTTGGCTCAAACAACTTTAAAGAAACAACGCGATCGACCT
TCAGAGGCTGCCTTGCTTGCAGGAATCTCAAACCATCAATTGCGCCAATCACTCTCATTAGCGGTTACTGTTGAGAAATG
CATTGCAGAGGTGGCCTTGCCTACTTCTTCGTCCCTGGCCCGTATCCATGGACAACTTGAGGTTGGCTTGCATCAGGGTG
GTCGACGTTTAACGCCTCAAAGACGCCGCGTTCTTGATCTCTTTGAAAGTATTGGTTCTGGCATTCACCTCAGTGCTGAA
GAAGTGCATCGGCAACTTCTAGAAGCAAACTCGAAGGTGTCTCTAGCAACGATCTACCGCACGCTGCGCTTGCTTGTCGA
CATGGGCTTTCTACACGAGTTGGAAATAAGCGATGGCGGACATCGCTTTGAATTAGCAAGTCACGACCATCCTGATCATC
ACCATTTGGTATGCGTGCGTTGTGGTCGTACTGAGGAGTTTGAGAGCAAACCAGTACTGGAAGCTGGACGCTCTGCTGCT
GAGCGAATCGGGTTCCAACTGATCGAGTCAACCTTGAATGTAAGGGCTCTATGTCCGTCTTGTCAGAGACCCTCTACAAC
CAATGTCCATTGA

Upstream 100 bases:

>100_bases
CACAGACTCTCGCAGCACATCCCACAGACAAAGCATCTCACAACCTTTTAGGCCACAAAGATAAGCACTCTTTGATCAAC
TTCAAGGTGTTAGCTGTCAC

Downstream 100 bases:

>100_bases
TGGCTGATGACAAACATCAATGCTGAGAATGCTGATCGCACGGCATCCAATGGGTTCCCATCTGGTGAACGCCTTTGCAT
CCCAACTCACGTGCCTTCAC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MPSQRTGNNQQAVAKVIKGQTIWPYTDFYFAGWGLASNKYHLTCRRGYNSLVALSGLATKAEGSTIGLAQTTLKKQRDRP
SEAALLAGISNHQLRQSLSLAVTVEKCIAEVALPTSSSLARIHGQLEVGLHQGGRRLTPQRRRVLDLFESIGSGIHLSAE
EVHRQLLEANSKVSLATIYRTLRLLVDMGFLHELEISDGGHRFELASHDHPDHHHLVCVRCGRTEEFESKPVLEAGRSAA
ERIGFQLIESTLNVRALCPSCQRPSTTNVH

Sequences:

>Translated_270_residues
MPSQRTGNNQQAVAKVIKGQTIWPYTDFYFAGWGLASNKYHLTCRRGYNSLVALSGLATKAEGSTIGLAQTTLKKQRDRP
SEAALLAGISNHQLRQSLSLAVTVEKCIAEVALPTSSSLARIHGQLEVGLHQGGRRLTPQRRRVLDLFESIGSGIHLSAE
EVHRQLLEANSKVSLATIYRTLRLLVDMGFLHELEISDGGHRFELASHDHPDHHHLVCVRCGRTEEFESKPVLEAGRSAA
ERIGFQLIESTLNVRALCPSCQRPSTTNVH
>Mature_269_residues
PSQRTGNNQQAVAKVIKGQTIWPYTDFYFAGWGLASNKYHLTCRRGYNSLVALSGLATKAEGSTIGLAQTTLKKQRDRPS
EAALLAGISNHQLRQSLSLAVTVEKCIAEVALPTSSSLARIHGQLEVGLHQGGRRLTPQRRRVLDLFESIGSGIHLSAEE
VHRQLLEANSKVSLATIYRTLRLLVDMGFLHELEISDGGHRFELASHDHPDHHHLVCVRCGRTEEFESKPVLEAGRSAAE
RIGFQLIESTLNVRALCPSCQRPSTTNVH

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=28.6821705426357, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 29771; Mature: 29640

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSQRTGNNQQAVAKVIKGQTIWPYTDFYFAGWGLASNKYHLTCRRGYNSLVALSGLATK
CCCCCCCCCHHHHHHHHCCCEECCCCCHHEECCCCCCCCEEEEEECCCCCEEHHHCCCCC
AEGSTIGLAQTTLKKQRDRPSEAALLAGISNHQLRQSLSLAVTVEKCIAEVALPTSSSLA
CCCCEECHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
RIHGQLEVGLHQGGRRLTPQRRRVLDLFESIGSGIHLSAEEVHRQLLEANSKVSLATIYR
HHHHHEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCHHHHHHH
TLRLLVDMGFLHELEISDGGHRFELASHDHPDHHHLVCVRCGRTEEFESKPVLEAGRSAA
HHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
ERIGFQLIESTLNVRALCPSCQRPSTTNVH
HHHHHHHHHHHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure 
PSQRTGNNQQAVAKVIKGQTIWPYTDFYFAGWGLASNKYHLTCRRGYNSLVALSGLATK
CCCCCCCCHHHHHHHHCCCEECCCCCHHEECCCCCCCCEEEEEECCCCCEEHHHCCCCC
AEGSTIGLAQTTLKKQRDRPSEAALLAGISNHQLRQSLSLAVTVEKCIAEVALPTSSSLA
CCCCEECHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
RIHGQLEVGLHQGGRRLTPQRRRVLDLFESIGSGIHLSAEEVHRQLLEANSKVSLATIYR
HHHHHEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCHHHHHHH
TLRLLVDMGFLHELEISDGGHRFELASHDHPDHHHLVCVRCGRTEEFESKPVLEAGRSAA
HHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
ERIGFQLIESTLNVRALCPSCQRPSTTNVH
HHHHHHHHHHHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]