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The map label for this gene is ddc [H]

Identifier: 33862871

GI number: 33862871

Start: 653862

End: 655274

Strand: Reverse

Name: ddc [H]

Synonym: PMT0598

Alternate gene names: 33862871

Gene position: 655274-653862 (Counterclockwise)

Preceding gene: 33862873

Following gene: 33862866

Centisome position: 27.18

GC content: 54.71

Gene sequence:

>1413_bases
TTGGCTGGCACTCCCCAGATAAGGCCGACTGCGACCTTGGCGCCCTTTGCCAAGCCTGACCGTTTCGATCCAGAACTGCA
GACTTTTCTGGAGCAGGCCAGTGCTCGACTTTGTCAATGGTTCGCAACAGCAAGCAATCGAGGCCCCTTACCAGCGCTTA
GTGCTTTGCCTGATGTAGCGCCGCAGCCTCAAGGTCTTTCAGTTGATGCCTTGCTGGACGATTTGCAGTTGGTGATGGAA
GGGGCTTATCAGCCTTCCCATCCAGGTGCTTTGGCTCATCTCGATCCGCCTCCTCTAACGGCATCCATCGCTGCCGATTT
GATCTGCGCAGGGCTAAACAACAATCTTTTGGCCGAGGAGTTGTCACCCAGTCTTTCGCGTTTAGAGCGAGAGATGTGCC
GCTGGTTTGCTGAGCGCTTGGGGCTGCCGTTGACGGCTGGTGGTGTGGCAGCCAGTGGTGGCAGCCTCAGCAACCTCATG
GCGATGGTGATAGCTCGCCAACAGGCAGATCTTCAAGATGATCCCAGGGCAGTGGTGCTTGCAAGTGTCGACGCCCATGT
GTCACTCGCTAAGGCCATTCGGGTCATGGGATTGGCTAGCGATGCCTTGCAGACGGTGCCTGTCGATCAAAAGGGCTGCA
TGAATCTCGATGCCCTAGAGCATCAACTGAAAGCTCTCCGCGCAGAAGGGAGACCATGCTTAGCCGTTGTGGCGACAGCA
GGCACGACTGTCCAGGGAGCTGTAGATCCCTTGGTAGCGGTAGCAGAGCTATGCAGACGCGAGCAGGTCTGGTTGCATGT
CGATGGAGCCATTGGAGGGGTCTTTGCTCTAACAGCAGCCACTGCTTCTGTGGTTGAAGGAATCTCTCTAGCCGATTCGA
TCACAGTGAATCCTCAAAAGTTGCTTGGGATCACTAAGACATCATCCCTATTGCTAGTCGCGAACCAATCCCATCTTGCT
TCAGCCTTCTCGACTGGCTTGCCCTATATGGAACCAGCCTGGGGAGACGGTCATGGAAGTGAAATTGGCCTTCAAGGAAC
TCGGCCAGCAGAGGTGCTCAAGCTTTGGTTGGGTCTGCGTCAACTCGGGGAGCAGGGAATTCAGTGCTTGCTGGAGGGGG
CCATTCAGCGTCGTCAGTCGCTCGCGCGTCAACTCGATGCATCCAGGTTCATTCTTCTCAGCGGACCATTGCATCTGATT
GCCTGTACCCCTAAGAACGCCGATGCATATCAAGCATCAGTCTGGTCATTAGCAACTCGGCAAAGCTTGCTGGAACAGCA
GTTGATGGTGTCAAGACCCTTGCATCATGGTCGTCATTTCCTCAAGGTGGTCTTGGGCAACCCCCATACGCAATCGATTC
ATCTCAATCGGTTGGCAACTCTGATGAATCAATCTTTGCTGGGTTTGCGCTAA

Upstream 100 bases:

>100_bases
TGGTTAGTTCAAGAGGTTGCGCTAAAGGCACCGCTAAGTGGCAGCTCCTGATCAAACAATGCCATCAGGAGGGAGAATGG
AACTTGTATGACGAGCGTTA

Downstream 100 bases:

>100_bases
TGGCTTCATCACCCCCACGAGGCCGCTGGGTGGCGATTATCACGACTGTTTTATCAGTAGCGATTGGATTGTTCTACCTG
GCTTTGATCACAGTTCTGGA

Product: pyridoxal-dependent decarboxylase family protein

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MAGTPQIRPTATLAPFAKPDRFDPELQTFLEQASARLCQWFATASNRGPLPALSALPDVAPQPQGLSVDALLDDLQLVME
GAYQPSHPGALAHLDPPPLTASIAADLICAGLNNNLLAEELSPSLSRLEREMCRWFAERLGLPLTAGGVAASGGSLSNLM
AMVIARQQADLQDDPRAVVLASVDAHVSLAKAIRVMGLASDALQTVPVDQKGCMNLDALEHQLKALRAEGRPCLAVVATA
GTTVQGAVDPLVAVAELCRREQVWLHVDGAIGGVFALTAATASVVEGISLADSITVNPQKLLGITKTSSLLLVANQSHLA
SAFSTGLPYMEPAWGDGHGSEIGLQGTRPAEVLKLWLGLRQLGEQGIQCLLEGAIQRRQSLARQLDASRFILLSGPLHLI
ACTPKNADAYQASVWSLATRQSLLEQQLMVSRPLHHGRHFLKVVLGNPHTQSIHLNRLATLMNQSLLGLR

Sequences:

>Translated_470_residues
MAGTPQIRPTATLAPFAKPDRFDPELQTFLEQASARLCQWFATASNRGPLPALSALPDVAPQPQGLSVDALLDDLQLVME
GAYQPSHPGALAHLDPPPLTASIAADLICAGLNNNLLAEELSPSLSRLEREMCRWFAERLGLPLTAGGVAASGGSLSNLM
AMVIARQQADLQDDPRAVVLASVDAHVSLAKAIRVMGLASDALQTVPVDQKGCMNLDALEHQLKALRAEGRPCLAVVATA
GTTVQGAVDPLVAVAELCRREQVWLHVDGAIGGVFALTAATASVVEGISLADSITVNPQKLLGITKTSSLLLVANQSHLA
SAFSTGLPYMEPAWGDGHGSEIGLQGTRPAEVLKLWLGLRQLGEQGIQCLLEGAIQRRQSLARQLDASRFILLSGPLHLI
ACTPKNADAYQASVWSLATRQSLLEQQLMVSRPLHHGRHFLKVVLGNPHTQSIHLNRLATLMNQSLLGLR
>Mature_469_residues
AGTPQIRPTATLAPFAKPDRFDPELQTFLEQASARLCQWFATASNRGPLPALSALPDVAPQPQGLSVDALLDDLQLVMEG
AYQPSHPGALAHLDPPPLTASIAADLICAGLNNNLLAEELSPSLSRLEREMCRWFAERLGLPLTAGGVAASGGSLSNLMA
MVIARQQADLQDDPRAVVLASVDAHVSLAKAIRVMGLASDALQTVPVDQKGCMNLDALEHQLKALRAEGRPCLAVVATAG
TTVQGAVDPLVAVAELCRREQVWLHVDGAIGGVFALTAATASVVEGISLADSITVNPQKLLGITKTSSLLLVANQSHLAS
AFSTGLPYMEPAWGDGHGSEIGLQGTRPAEVLKLWLGLRQLGEQGIQCLLEGAIQRRQSLARQLDASRFILLSGPLHLIA
CTPKNADAYQASVWSLATRQSLLEQQLMVSRPLHHGRHFLKVVLGNPHTQSIHLNRLATLMNQSLLGLR

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197276620, Length=423, Percent_Identity=27.8959810874704, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI4503875, Length=423, Percent_Identity=27.8959810874704, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI194294551, Length=443, Percent_Identity=28.4424379232506, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI197383062, Length=367, Percent_Identity=28.6103542234332, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI58331246, Length=351, Percent_Identity=23.6467236467236, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4503281, Length=358, Percent_Identity=26.2569832402235, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI132814448, Length=358, Percent_Identity=26.2569832402235, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI92110055, Length=366, Percent_Identity=28.4153005464481, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI31982936, Length=390, Percent_Identity=23.5897435897436, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71993058, Length=355, Percent_Identity=28.4507042253521, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17555682, Length=355, Percent_Identity=28.4507042253521, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71993062, Length=321, Percent_Identity=29.9065420560748, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17534819, Length=416, Percent_Identity=24.0384615384615, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534817, Length=416, Percent_Identity=24.0384615384615, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI133931025, Length=391, Percent_Identity=25.5754475703325, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17136594, Length=365, Percent_Identity=29.041095890411, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24657193, Length=371, Percent_Identity=27.2237196765499, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24657185, Length=371, Percent_Identity=27.2237196765499, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24657188, Length=371, Percent_Identity=27.2237196765499, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573972, Length=390, Percent_Identity=27.1794871794872, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356415, Length=322, Percent_Identity=29.5031055900621, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136190, Length=447, Percent_Identity=23.9373601789709, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24585135, Length=440, Percent_Identity=24.0909090909091, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586044, Length=371, Percent_Identity=25.6064690026954, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24585139, Length=414, Percent_Identity=24.1545893719807, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221476190, Length=393, Percent_Identity=23.9185750636132, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24585143, Length=393, Percent_Identity=23.9185750636132, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24652373, Length=365, Percent_Identity=24.6575342465753, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 49956; Mature: 49825

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTPQIRPTATLAPFAKPDRFDPELQTFLEQASARLCQWFATASNRGPLPALSALPDVA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
PQPQGLSVDALLDDLQLVMEGAYQPSHPGALAHLDPPPLTASIAADLICAGLNNNLLAEE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
LSPSLSRLEREMCRWFAERLGLPLTAGGVAASGGSLSNLMAMVIARQQADLQDDPRAVVL
HCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
ASVDAHVSLAKAIRVMGLASDALQTVPVDQKGCMNLDALEHQLKALRAEGRPCLAVVATA
EECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEC
GTTVQGAVDPLVAVAELCRREQVWLHVDGAIGGVFALTAATASVVEGISLADSITVNPQK
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LLGITKTSSLLLVANQSHLASAFSTGLPYMEPAWGDGHGSEIGLQGTRPAEVLKLWLGLR
HEEEECCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QLGEQGIQCLLEGAIQRRQSLARQLDASRFILLSGPLHLIACTPKNADAYQASVWSLATR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHH
QSLLEQQLMVSRPLHHGRHFLKVVLGNPHTQSIHLNRLATLMNQSLLGLR
HHHHHHHHHHHCCHHHHHHEEEEEECCCCCCEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGTPQIRPTATLAPFAKPDRFDPELQTFLEQASARLCQWFATASNRGPLPALSALPDVA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
PQPQGLSVDALLDDLQLVMEGAYQPSHPGALAHLDPPPLTASIAADLICAGLNNNLLAEE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
LSPSLSRLEREMCRWFAERLGLPLTAGGVAASGGSLSNLMAMVIARQQADLQDDPRAVVL
HCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
ASVDAHVSLAKAIRVMGLASDALQTVPVDQKGCMNLDALEHQLKALRAEGRPCLAVVATA
EECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEC
GTTVQGAVDPLVAVAELCRREQVWLHVDGAIGGVFALTAATASVVEGISLADSITVNPQK
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LLGITKTSSLLLVANQSHLASAFSTGLPYMEPAWGDGHGSEIGLQGTRPAEVLKLWLGLR
HEEEECCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QLGEQGIQCLLEGAIQRRQSLARQLDASRFILLSGPLHLIACTPKNADAYQASVWSLATR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHH
QSLLEQQLMVSRPLHHGRHFLKVVLGNPHTQSIHLNRLATLMNQSLLGLR
HHHHHHHHHHHCCHHHHHHEEEEEECCCCCCEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8772175 [H]