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The map label for this gene is folB [H]

Identifier: 33862708

GI number: 33862708

Start: 489919

End: 490332

Strand: Reverse

Name: folB [H]

Synonym: PMT0435

Alternate gene names: 33862708

Gene position: 490332-489919 (Counterclockwise)

Preceding gene: 33862709

Following gene: 33862707

Centisome position: 20.34

GC content: 52.17

Gene sequence:

>414_bases
ATGCATGTTCACTCACCGGGACCTACCGCTGTGATCAATCGTCTCCCTTTAGGAGCCATTCATGTTAACGATGTGCGCTT
GTGGGCCCACGTGGGTGTGCTTGACCATGAAAGACGTGAAGGCCAGTGGTTCAGCTTGGATTTCAGCCTTTGGTTAGACC
TTGACAAGGCTGCCCTGGATGATGAGCTCAATGCCACTGCGGACTACAGCTTGGCTATTGGTGCAATGCAACGACTCTCC
TTTGAACTGAAGTGTTTTACCATCGAACACTTCAGCGAGCGATTGCTAGTGCTCTTGGAAGATCTCTACGGTCCTGTGCC
AATGCAAGTGCTTGTGCGTAAATGTGCTGCGCCGGTGCCTGGGTTTAGTGGCAGTGTGGCTGTTGAAAGGTGTCGCAATT
GGCCAACACCCTGA

Upstream 100 bases:

>100_bases
CACTGCCTCCAAGGGGGCCGGTTGGCTTGGAAGGGCTGGTGACCTATCGCTATCGGTTACGTGGACAAGGCCACATTGTG
GCGGACTATGCCAATGGTGA

Downstream 100 bases:

>100_bases
TCTTTGCCAAGGCTTTTAGCGATGTTTACGCATGTCGCATCAGTGGATAAACCCCGTCGACCATTGGTGCTTGTACATGG
TCTTTGGGATACCCCGCATC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MHVHSPGPTAVINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDELNATADYSLAIGAMQRLS
FELKCFTIEHFSERLLVLLEDLYGPVPMQVLVRKCAAPVPGFSGSVAVERCRNWPTP

Sequences:

>Translated_137_residues
MHVHSPGPTAVINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDELNATADYSLAIGAMQRLS
FELKCFTIEHFSERLLVLLEDLYGPVPMQVLVRKCAAPVPGFSGSVAVERCRNWPTP
>Mature_137_residues
MHVHSPGPTAVINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALDDELNATADYSLAIGAMQRLS
FELKCFTIEHFSERLLVLLEDLYGPVPMQVLVRKCAAPVPGFSGSVAVERCRNWPTP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 15374; Mature: 15374

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVHSPGPTAVINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALD
CCCCCCCCHHHHHCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEEEEEEEEECCHHHCC
DELNATADYSLAIGAMQRLSFELKCFTIEHFSERLLVLLEDLYGPVPMQVLVRKCAAPVP
CCCCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
GFSGSVAVERCRNWPTP
CCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MHVHSPGPTAVINRLPLGAIHVNDVRLWAHVGVLDHERREGQWFSLDFSLWLDLDKAALD
CCCCCCCCHHHHHCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEEEEEEEEECCHHHCC
DELNATADYSLAIGAMQRLSFELKCFTIEHFSERLLVLLEDLYGPVPMQVLVRKCAAPVP
CCCCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
GFSGSVAVERCRNWPTP
CCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]