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The map label for this gene is pdxA [H]

Identifier: 33862306

GI number: 33862306

Start: 35200

End: 36231

Strand: Reverse

Name: pdxA [H]

Synonym: PMT0033

Alternate gene names: 33862306

Gene position: 36231-35200 (Counterclockwise)

Preceding gene: 33862307

Following gene: 33862303

Centisome position: 1.5

GC content: 54.65

Gene sequence:

>1032_bases
ATGGCTATGCCTTCTGAAGGCTTTGACGCTAATCAACTTATCGTTATCGCCATCGGCGATCCCGCTGGCATCGGGATGGA
GGTCACCCTAAAGGCCCTCGCTTCACCAAGCTTGCCATCAAAGCTGCATCCCCAGCTGGTTGGCTGTCGAAAAAGCCTAG
AACTGACCTATGCCCAATTACAAGCTCAAGGGATCTCTCCCCTAGCCAATCCAAAGAACCTCGACATCAAAGATCTACCC
CTGCAGAGCACACTTCAGCCTGGATACCCCACAGCACAGAGTGGAGCCGCAAGCTTTCTATGGTTGACAAAGGCAACAGA
ACTCCTCTTGAAGGGTCGAGCCCGCGCCCTTGTTACCGCTCCTATTGCCAAGCAGGCCTGGCATGCAGCAGGCCATCACT
ATCCCGGTCAAACCGAACGACTTAAAGAACTGGTGGGAGCTGATCAAGCCTCCATGCTCTTCACCGCGATCTCACCTCAT
AACGGCTGGCGGTTCAACACTCTGCTAGCAACAACCCATATCCCGCTAGCAGCAGTCCCACAAGTGCTTACCCCTGAGTT
GGTTAGAGCGAAGCTCAACGTACTCAAGGCATTCTGCCAAAGATTCAAAACCGATCCATCCATTGCAGTCGCAGGCCTCA
ATCCCCACGCTGGCGAGCAAGGCCAACTGGGCCATGAAGAGCTGAAATGGTTGATCCCAATGCTGAACAGATGGAAAACG
GAGCACCCTGAGATCCAACTAGACGGTCCTTTACCTCCCGACACATGTTGGCTTTCAGCTGCAAAGGCTTGGCATGGCAT
CCCTTGCGCCCAAACCCCAGACGGGATCCTGGCCTTATACCACGATCAAGGTCTAATCCCAATGAAGCTGCTGGCTTTCG
ACTCGGCCGTCAACACCACCCTTGGGCTTCCATTTCTACGTACCTCACCTGATCACGGCACCGCCTTTGACATTGCCGGA
AAGGGATGTGCCAGACCCGACAGCATGTTGGCCGCCCTAAAAGCCGCCTGGGAGCTCACGGAATCACGCTGA

Upstream 100 bases:

>100_bases
GGCATCGCGCAAAAACTGACTCCAATGCACCACCAACCAACCATTCCGCAATCCGGTACCAAGACCAAACAACAGCAAAC
CAAGCAGCAACCAGCGCATC

Downstream 100 bases:

>100_bases
TCAGCCAGGCTTAACACGCATCAAAACCTGACCGAACTCAACTGGCGTGCCGTTATCTACAAGGATTTCAACCACCTCGC
CACTGACTTCAGATTCCAAC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAMPSEGFDANQLIVIAIGDPAGIGMEVTLKALASPSLPSKLHPQLVGCRKSLELTYAQLQAQGISPLANPKNLDIKDLP
LQSTLQPGYPTAQSGAASFLWLTKATELLLKGRARALVTAPIAKQAWHAAGHHYPGQTERLKELVGADQASMLFTAISPH
NGWRFNTLLATTHIPLAAVPQVLTPELVRAKLNVLKAFCQRFKTDPSIAVAGLNPHAGEQGQLGHEELKWLIPMLNRWKT
EHPEIQLDGPLPPDTCWLSAAKAWHGIPCAQTPDGILALYHDQGLIPMKLLAFDSAVNTTLGLPFLRTSPDHGTAFDIAG
KGCARPDSMLAALKAAWELTESR

Sequences:

>Translated_343_residues
MAMPSEGFDANQLIVIAIGDPAGIGMEVTLKALASPSLPSKLHPQLVGCRKSLELTYAQLQAQGISPLANPKNLDIKDLP
LQSTLQPGYPTAQSGAASFLWLTKATELLLKGRARALVTAPIAKQAWHAAGHHYPGQTERLKELVGADQASMLFTAISPH
NGWRFNTLLATTHIPLAAVPQVLTPELVRAKLNVLKAFCQRFKTDPSIAVAGLNPHAGEQGQLGHEELKWLIPMLNRWKT
EHPEIQLDGPLPPDTCWLSAAKAWHGIPCAQTPDGILALYHDQGLIPMKLLAFDSAVNTTLGLPFLRTSPDHGTAFDIAG
KGCARPDSMLAALKAAWELTESR
>Mature_342_residues
AMPSEGFDANQLIVIAIGDPAGIGMEVTLKALASPSLPSKLHPQLVGCRKSLELTYAQLQAQGISPLANPKNLDIKDLPL
QSTLQPGYPTAQSGAASFLWLTKATELLLKGRARALVTAPIAKQAWHAAGHHYPGQTERLKELVGADQASMLFTAISPHN
GWRFNTLLATTHIPLAAVPQVLTPELVRAKLNVLKAFCQRFKTDPSIAVAGLNPHAGEQGQLGHEELKWLIPMLNRWKTE
HPEIQLDGPLPPDTCWLSAAKAWHGIPCAQTPDGILALYHDQGLIPMKLLAFDSAVNTTLGLPFLRTSPDHGTAFDIAGK
GCARPDSMLAALKAAWELTESR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=342, Percent_Identity=33.9181286549708, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36934; Mature: 36803

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMPSEGFDANQLIVIAIGDPAGIGMEVTLKALASPSLPSKLHPQLVGCRKSLELTYAQL
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHH
QAQGISPLANPKNLDIKDLPLQSTLQPGYPTAQSGAASFLWLTKATELLLKGRARALVTA
HHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEC
PIAKQAWHAAGHHYPGQTERLKELVGADQASMLFTAISPHNGWRFNTLLATTHIPLAAVP
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCEEEEEEEEECCCCHHHCC
QVLTPELVRAKLNVLKAFCQRFKTDPSIAVAGLNPHAGEQGQLGHEELKWLIPMLNRWKT
HHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
EHPEIQLDGPLPPDTCWLSAAKAWHGIPCAQTPDGILALYHDQGLIPMKLLAFDSAVNTT
CCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LGLPFLRTSPDHGTAFDIAGKGCARPDSMLAALKAAWELTESR
HCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AMPSEGFDANQLIVIAIGDPAGIGMEVTLKALASPSLPSKLHPQLVGCRKSLELTYAQL
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHH
QAQGISPLANPKNLDIKDLPLQSTLQPGYPTAQSGAASFLWLTKATELLLKGRARALVTA
HHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEC
PIAKQAWHAAGHHYPGQTERLKELVGADQASMLFTAISPHNGWRFNTLLATTHIPLAAVP
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCEEEEEEEEECCCCHHHCC
QVLTPELVRAKLNVLKAFCQRFKTDPSIAVAGLNPHAGEQGQLGHEELKWLIPMLNRWKT
HHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
EHPEIQLDGPLPPDTCWLSAAKAWHGIPCAQTPDGILALYHDQGLIPMKLLAFDSAVNTT
CCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LGLPFLRTSPDHGTAFDIAGKGCARPDSMLAALKAAWELTESR
HCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA