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The map label for this gene is mqo

Identifier: 32267219

GI number: 32267219

Start: 1645523

End: 1647007

Strand: Direct

Name: mqo

Synonym: HH1720

Alternate gene names: 32267219

Gene position: 1645523-1647007 (Clockwise)

Preceding gene: 32267218

Following gene: 32267220

Centisome position: 91.46

GC content: 37.64

Gene sequence:

>1485_bases
ATGAGTGAGGATTCTGAAGTAGTCTTAGTAGGTGGAGGCATAATGAGTTTGACTTTGGCAGCAATGCTAAGGGAGCTCAA
ACCTTCTTTACATATCAGCGTGTATGAAATGTTTGAGGATTTAGCTACTGAAAGTAGTTCGGTATGGAACAATGCAGGAA
CAGGACATCAAGCACTTTGTGAGCTTAACTATACGCCACAAAAAGAAGATGGCAGTATTGATGTTTCAAAAGCATTAAAG
ATTAATCAGCAATTTGAATTAAGTAAAGAATTTTGGGCATATTGTATTAGAAAGCAGATTCTCAAAGGTGCTCATACTTT
TTTGAATCCTGTGCCGCATTTGAGCTTTGTCGTTGATGATATTGTGCCTTATTTGAAAAAACGTTATGAAACACTTAAAG
ATTCTCCGCTTTTTAAAAATATGATTTATACTGAAGATAGAGAGCAGATTAAAGAATGGGCACCACTTTTACTTGAGGGA
CGAGGCGAGACACAAAAGATGGCAGTTACTTATATGGCTGGTGGAAGTGATGTTGATTTTGGTGAAATTGCACGGCAGTT
TGGAGAAAAATTAAGCCAAAAAGAGGGTTTTGATGTTTATACTCATCATAAAGTGCGTGATTTAACCAAAGAGGGCAATA
TATGGTTATTAGATGTTATTGATACTAAAAGCTATGAGAGAAAACAAGTAAAGGCAAAATTTGTATTTTTAGGTGCGGGG
GGAGGTTCTTTTCCGCTCTTGCAAAAAAGTGGCATACCCGAAGGGCGTGGCTATGGTGGATTCCCTGTGGGTGGTTTATG
GCTTATATGTAATAATCGCGAAATTATTGAAAAACATAATGCTAAGATTTATGGTAAAGCATCTATTGGCGACCCGCCTA
TGTCTGTGCCACATTTAGATACGCGTATTATCAGGGGCAAAAAAGAATTGCTTTTTGGGCCTTATGCAGGATTTAATACG
AAATTTCTTAAAAAAGGAAGTTTTTTTGATTTTCCCTCATCAATCCGTTTAAATAATTTTATTCCTATGATTCAAGCAGG
TATTGACAATGTGCCATTGACAATTTACCTTATTAAGCAGATTCTCTCAACTGATAGAATGCGTATGCGTAAGCTTGAAG
TATTTTTCCCTGCGGCGCAGTTTCCAGATTGGAATGCGCAGTTTGCAGGGCAAAGGGTGCAAGTAATTAAAAAAGATAAA
AATGGTAGAGGAAGTTTGCAATTTGGCACGGAAGTGATTACTTCTAGCGATGGCTCTCTTGCAGCATTACTTGGAGCTTC
ACCGGGAGCTTCAACGGTGGTAGATATTATGTTAGAAGTGCTTAAACGTTGCTTTGGTGATGAAATGAAAACAAGCGCTT
GGCAAGATAAGCTTGCTGAAATGGTGCCTTCTTATAATCGTTCTCTTGAGGAAAATATCACTCATTTTAATGAATGTCGT
TTAAAAACAGCCCAAACGCTTCATTTGCCTTTTGATGAAATTTGA

Upstream 100 bases:

>100_bases
AGGCTAAATGAGAGCAAAAAGCATAATCCCCAATAGCGCAAGCATATTTAAGGTTTTTAAAACCTAGCCCAGAGCGTGGG
TATTAAGAAGGAGTGAGGGA

Downstream 100 bases:

>100_bases
ATCTAAAACACAGTAGCTTTTTAGAAGCTTAAAAAACCCTAAAAGGGTATTATAAATGTAATTTGTTTGTTTAGAGTTAA
TGTATATAATTCTCATTTAT

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSEDSEVVLVGGGIMSLTLAAMLRELKPSLHISVYEMFEDLATESSSVWNNAGTGHQALCELNYTPQKEDGSIDVSKALK
INQQFELSKEFWAYCIRKQILKGAHTFLNPVPHLSFVVDDIVPYLKKRYETLKDSPLFKNMIYTEDREQIKEWAPLLLEG
RGETQKMAVTYMAGGSDVDFGEIARQFGEKLSQKEGFDVYTHHKVRDLTKEGNIWLLDVIDTKSYERKQVKAKFVFLGAG
GGSFPLLQKSGIPEGRGYGGFPVGGLWLICNNREIIEKHNAKIYGKASIGDPPMSVPHLDTRIIRGKKELLFGPYAGFNT
KFLKKGSFFDFPSSIRLNNFIPMIQAGIDNVPLTIYLIKQILSTDRMRMRKLEVFFPAAQFPDWNAQFAGQRVQVIKKDK
NGRGSLQFGTEVITSSDGSLAALLGASPGASTVVDIMLEVLKRCFGDEMKTSAWQDKLAEMVPSYNRSLEENITHFNECR
LKTAQTLHLPFDEI

Sequences:

>Translated_494_residues
MSEDSEVVLVGGGIMSLTLAAMLRELKPSLHISVYEMFEDLATESSSVWNNAGTGHQALCELNYTPQKEDGSIDVSKALK
INQQFELSKEFWAYCIRKQILKGAHTFLNPVPHLSFVVDDIVPYLKKRYETLKDSPLFKNMIYTEDREQIKEWAPLLLEG
RGETQKMAVTYMAGGSDVDFGEIARQFGEKLSQKEGFDVYTHHKVRDLTKEGNIWLLDVIDTKSYERKQVKAKFVFLGAG
GGSFPLLQKSGIPEGRGYGGFPVGGLWLICNNREIIEKHNAKIYGKASIGDPPMSVPHLDTRIIRGKKELLFGPYAGFNT
KFLKKGSFFDFPSSIRLNNFIPMIQAGIDNVPLTIYLIKQILSTDRMRMRKLEVFFPAAQFPDWNAQFAGQRVQVIKKDK
NGRGSLQFGTEVITSSDGSLAALLGASPGASTVVDIMLEVLKRCFGDEMKTSAWQDKLAEMVPSYNRSLEENITHFNECR
LKTAQTLHLPFDEI
>Mature_493_residues
SEDSEVVLVGGGIMSLTLAAMLRELKPSLHISVYEMFEDLATESSSVWNNAGTGHQALCELNYTPQKEDGSIDVSKALKI
NQQFELSKEFWAYCIRKQILKGAHTFLNPVPHLSFVVDDIVPYLKKRYETLKDSPLFKNMIYTEDREQIKEWAPLLLEGR
GETQKMAVTYMAGGSDVDFGEIARQFGEKLSQKEGFDVYTHHKVRDLTKEGNIWLLDVIDTKSYERKQVKAKFVFLGAGG
GSFPLLQKSGIPEGRGYGGFPVGGLWLICNNREIIEKHNAKIYGKASIGDPPMSVPHLDTRIIRGKKELLFGPYAGFNTK
FLKKGSFFDFPSSIRLNNFIPMIQAGIDNVPLTIYLIKQILSTDRMRMRKLEVFFPAAQFPDWNAQFAGQRVQVIKKDKN
GRGSLQFGTEVITSSDGSLAALLGASPGASTVVDIMLEVLKRCFGDEMKTSAWQDKLAEMVPSYNRSLEENITHFNECRL
KTAQTLHLPFDEI

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=493, Percent_Identity=47.4645030425963, Blast_Score=497, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_HELHP (Q7VFF6)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_861251.1
- ProteinModelPortal:   Q7VFF6
- GeneID:   1492267
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1720
- NMPDR:   fig|235279.1.peg.1720
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BioCyc:   HHEP235279:HH_1720-MONOMER
- BRENDA:   1.1.99.16
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 55521; Mature: 55389

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDSEVVLVGGGIMSLTLAAMLRELKPSLHISVYEMFEDLATESSSVWNNAGTGHQALC
CCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCEEE
ELNYTPQKEDGSIDVSKALKINQQFELSKEFWAYCIRKQILKGAHTFLNPVPHLSFVVDD
ECCCCCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IVPYLKKRYETLKDSPLFKNMIYTEDREQIKEWAPLLLEGRGETQKMAVTYMAGGSDVDF
HHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHCCEEEECCCCCEEEEEEEEECCCCCCH
GEIARQFGEKLSQKEGFDVYTHHKVRDLTKEGNIWLLDVIDTKSYERKQVKAKFVFLGAG
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCEEEEEEECCCCHHHHEEEEEEEEEECC
GGSFPLLQKSGIPEGRGYGGFPVGGLWLICNNREIIEKHNAKIYGKASIGDPPMSVPHLD
CCCCCCHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCCCEEEEECCCCCCCCCCCCCH
TRIIRGKKELLFGPYAGFNTKFLKKGSFFDFPSSIRLNNFIPMIQAGIDNVPLTIYLIKQ
HHHHCCCHHHEECCCCCCCCHHCCCCCCCCCCCCCCHHCCHHHHHCCCCCCCCHHHHHHH
ILSTDRMRMRKLEVFFPAAQFPDWNAQFAGQRVQVIKKDKNGRGSLQFGTEVITSSDGSL
HHHHHHHHHHHHHEEECCCCCCCCCHHHCCCEEEEEEECCCCCCCEEECCEEEECCCCCE
AALLGASPGASTVVDIMLEVLKRCFGDEMKTSAWQDKLAEMVPSYNRSLEENITHFNECR
EEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LKTAQTLHLPFDEI
HHHHHEECCCHHCC
>Mature Secondary Structure 
SEDSEVVLVGGGIMSLTLAAMLRELKPSLHISVYEMFEDLATESSSVWNNAGTGHQALC
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCEEE
ELNYTPQKEDGSIDVSKALKINQQFELSKEFWAYCIRKQILKGAHTFLNPVPHLSFVVDD
ECCCCCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IVPYLKKRYETLKDSPLFKNMIYTEDREQIKEWAPLLLEGRGETQKMAVTYMAGGSDVDF
HHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHCCEEEECCCCCEEEEEEEEECCCCCCH
GEIARQFGEKLSQKEGFDVYTHHKVRDLTKEGNIWLLDVIDTKSYERKQVKAKFVFLGAG
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCEEEEEEECCCCHHHHEEEEEEEEEECC
GGSFPLLQKSGIPEGRGYGGFPVGGLWLICNNREIIEKHNAKIYGKASIGDPPMSVPHLD
CCCCCCHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCCCEEEEECCCCCCCCCCCCCH
TRIIRGKKELLFGPYAGFNTKFLKKGSFFDFPSSIRLNNFIPMIQAGIDNVPLTIYLIKQ
HHHHCCCHHHEECCCCCCCCHHCCCCCCCCCCCCCCHHCCHHHHHCCCCCCCCHHHHHHH
ILSTDRMRMRKLEVFFPAAQFPDWNAQFAGQRVQVIKKDKNGRGSLQFGTEVITSSDGSL
HHHHHHHHHHHHHEEECCCCCCCCCHHHCCCEEEEEEECCCCCCCEEECCEEEECCCCCE
AALLGASPGASTVVDIMLEVLKRCFGDEMKTSAWQDKLAEMVPSYNRSLEENITHFNECR
EEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LKTAQTLHLPFDEI
HHHHHEECCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954