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The map label for this gene is htpX

Identifier: 32267210

GI number: 32267210

Start: 1637704

End: 1638633

Strand: Direct

Name: htpX

Synonym: HH1711

Alternate gene names: 32267210

Gene position: 1637704-1638633 (Clockwise)

Preceding gene: 32267209

Following gene: 32267211

Centisome position: 91.03

GC content: 37.63

Gene sequence:

>930_bases
ATGAACTCCCATTTTGAACGAATTATTGCTCAAAATAAGCTTAAAACTTATGCGGTTTTGGCTATATATATCATCATTTT
TATACTTATTGGTTTGCTTGCAGATATTATTCGCATTGACGCTCCTAGCTTACAAGAGGGGTTTATAATGCTTCTTAGTT
TTTATGAATTTCCTCTTATTACCTTTGGAATGGCAGTGGTGGCAGTGGGCATTATTCTTTTTAGCGTGCAGCGTTTCTCA
CGCATTATGCTAAGTGGCAATGAATATAAACGCATTAATCCTAATAATGTGCTCTCTCGTCAAGAATCTCGCCTGTATGG
TGTATTTCAAGATTTACTTAGAAGTGCAAATTGTTCTTTTGAACCCGCACTTTATATTATGGAAGCCCCTTATATGAATG
CTTTTGCGAGTGGGTGGAATGAAAAAAATTCTATGATTGCTGTTACTTCAGCGTTGTTAGAGCGATTAGATGAGAGTGAG
CTAAAAGCGGTAGTAGCGCACGAGTTAAGCCATATTCGGCACGGAGATGTGCGATTAACGATGTGTGTAGGGATTTTAAG
CAACATTATGCTTTTAGGTGTGAATATTTTTGCCTTTTATTTTAGCTCTGCTCAATCTCAAGGAGCAAGGGCAGCACGAA
GTATTTTGCTCATTTTACAATTTGTCCTCCCACTTCTTACACTTGTGCTAAGCCTTTTTATCTCTCGTAATCGTGAATAT
ATGGCGGATTCTGGAGCAGCATATTTAATGAAAGAAAGTGAGCCAATGGTTCGGGCATTACAAAAAATTAGCCAAGATTA
TGCGCAAAATAATTATCAAGAGCCAAATCCCACACGAGCAAATGCCTATCTTTTCGGCATAGGTGAGATTCTAAGCACAC
ATCCAAGCATACAAAATCGTATAAAAGCATTACTTGGACAACATTTTTAA

Upstream 100 bases:

>100_bases
AATGTGCTTTTTTAGACATATCTTTCCTTTTTCAAAAATTTGCAAAACTTTGCCATAATATCACTTATTAAATAGTAAGT
TAAATATTAAGGAGGAGAGA

Downstream 100 bases:

>100_bases
GCAATGGATAAAATCGCACGAATAAGGTGAGATATAAACATTGAAATTAAAGCATAAGCAAAAATATTATACAATTTGCA
CAATGCAAAACGCGCAATTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNSHFERIIAQNKLKTYAVLAIYIIIFILIGLLADIIRIDAPSLQEGFIMLLSFYEFPLITFGMAVVAVGIILFSVQRFS
RIMLSGNEYKRINPNNVLSRQESRLYGVFQDLLRSANCSFEPALYIMEAPYMNAFASGWNEKNSMIAVTSALLERLDESE
LKAVVAHELSHIRHGDVRLTMCVGILSNIMLLGVNIFAFYFSSAQSQGARAARSILLILQFVLPLLTLVLSLFISRNREY
MADSGAAYLMKESEPMVRALQKISQDYAQNNYQEPNPTRANAYLFGIGEILSTHPSIQNRIKALLGQHF

Sequences:

>Translated_309_residues
MNSHFERIIAQNKLKTYAVLAIYIIIFILIGLLADIIRIDAPSLQEGFIMLLSFYEFPLITFGMAVVAVGIILFSVQRFS
RIMLSGNEYKRINPNNVLSRQESRLYGVFQDLLRSANCSFEPALYIMEAPYMNAFASGWNEKNSMIAVTSALLERLDESE
LKAVVAHELSHIRHGDVRLTMCVGILSNIMLLGVNIFAFYFSSAQSQGARAARSILLILQFVLPLLTLVLSLFISRNREY
MADSGAAYLMKESEPMVRALQKISQDYAQNNYQEPNPTRANAYLFGIGEILSTHPSIQNRIKALLGQHF
>Mature_309_residues
MNSHFERIIAQNKLKTYAVLAIYIIIFILIGLLADIIRIDAPSLQEGFIMLLSFYEFPLITFGMAVVAVGIILFSVQRFS
RIMLSGNEYKRINPNNVLSRQESRLYGVFQDLLRSANCSFEPALYIMEAPYMNAFASGWNEKNSMIAVTSALLERLDESE
LKAVVAHELSHIRHGDVRLTMCVGILSNIMLLGVNIFAFYFSSAQSQGARAARSILLILQFVLPLLTLVLSLFISRNREY
MADSGAAYLMKESEPMVRALQKISQDYAQNNYQEPNPTRANAYLFGIGEILSTHPSIQNRIKALLGQHF

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=295, Percent_Identity=27.4576271186441, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 34831; Mature: 34831

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHFERIIAQNKLKTYAVLAIYIIIFILIGLLADIIRIDAPSLQEGFIMLLSFYEFPLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TFGMAVVAVGIILFSVQRFSRIMLSGNEYKRINPNNVLSRQESRLYGVFQDLLRSANCSF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
EPALYIMEAPYMNAFASGWNEKNSMIAVTSALLERLDESELKAVVAHELSHIRHGDVRLT
CCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHH
MCVGILSNIMLLGVNIFAFYFSSAQSQGARAARSILLILQFVLPLLTLVLSLFISRNREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
MADSGAAYLMKESEPMVRALQKISQDYAQNNYQEPNPTRANAYLFGIGEILSTHPSIQNR
HHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHCCHHHHHH
IKALLGQHF
HHHHHCCCC
>Mature Secondary Structure
MNSHFERIIAQNKLKTYAVLAIYIIIFILIGLLADIIRIDAPSLQEGFIMLLSFYEFPLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TFGMAVVAVGIILFSVQRFSRIMLSGNEYKRINPNNVLSRQESRLYGVFQDLLRSANCSF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
EPALYIMEAPYMNAFASGWNEKNSMIAVTSALLERLDESELKAVVAHELSHIRHGDVRLT
CCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHH
MCVGILSNIMLLGVNIFAFYFSSAQSQGARAARSILLILQFVLPLLTLVLSLFISRNREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
MADSGAAYLMKESEPMVRALQKISQDYAQNNYQEPNPTRANAYLFGIGEILSTHPSIQNR
HHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHCCHHHHHH
IKALLGQHF
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]