Click here to switch to the map view.

The map label for this gene is actP

Identifier: 32267046

GI number: 32267046

Start: 1482209

End: 1483858

Strand: Direct

Name: actP

Synonym: HH1547

Alternate gene names: 32267046

Gene position: 1482209-1483858 (Clockwise)

Preceding gene: 32267045

Following gene: 32267048

Centisome position: 82.38

GC content: 36.61

Gene sequence:

>1650_bases
ATGAAAAGTTTATTTTTTAGCTTAAGCTTATTAAGTGTAAATTCGCTTTTTGGTGCATCTATTGATTTTGGTGGTGCAAA
ATCAGACATTAATCCAATAGCGATAGGTATGTTTTTAGCCTTTGTGCTTGCAACTTTATTTATTACTTATCTTTCTAACA
AAAAGAGTCAATCTGCAAGTGGTTTTTATACTGCAGGGGGTAATATCACTGGTATGCAAAATGGTGTAGCTATTGCTGGA
GATTATATGAGTGCAGCGAGCTTTTTAGGTATTACTGCGCTTGTATTTACAAATGGCTTTGATGGACTTATTTATTCCAT
AGGATTTTTAGCTGGGTGGCCTATCATTTTGTTTTTGATTGCTGAAAAATTTAGAAATTTGGGTAAATTCACTTTTGCTG
ACATTACTGCCTATCGTTTAGATGCAAAGCCTATTCGTATTATTTCTGCTATTTCTGCTTTGAGCGTTATAGTGTTTTAT
CTCATTGCACAAATGGTTGGTGCAGGACAGCTTATACAGGTGCTTTTTGGTTTACCTTATAGTGTAGCAGTGGTGCTTGT
GGGAATCTTAATGATTTGCTATGTCGTTTTTGGTGGAATGCACGCTACAACTTGGGTGCAAATTATTAAAGCAGTGTTGC
TTTTAGCAGGTGCAAGTTTTATGGCAATTATGATTTTGTATTTGACAAAATTTGACTTAAGCTACTACTTCTCACAGGCG
GTTTCACATCACCCTAAAGGAGAATCTATTATGTCGCCTGGAGGTTTTTTACCTGATAGTATTTCTGCAGTATCGCTTGG
GTTAGCTCTTATGTTTGGAACAGCAGGATTGCCTCATATTTTAATGAGATTTTTCACGGTAAAAGATGCCAAAGAAGCTC
GTAAATCTGTATTTTATGCAACAGGGTTAATTGGATATTTTTATATTCTAACTTTCATCATTGGTTTTGGTGCAATTGCA
CTTTTACTTGGGAATCCAGATTATACAGATGCAAATGGTGCTTATAATGGTGTTACAAATATGGTTGCTGTAAATCTTGC
TTCTGTGCTTGGCGGAGATTTCTTCTATGGCTTTATTTGTGCGGTGGCATTTGCTACAATTTTGGCAGTTGTTTCTGGAT
TGGCAATTACAGGTGCAGGTGCAATCAGCCACGATTTGTTTGTCAATGTTTGTAAAAATGGACAATGTGATCCTGCACTT
GAAATGAGAGTAACTAAAATCGCTACAATTTGTATTGGAATATGTGCAATTGCACTTGGCATTGTATTTGAAAAGCAAAA
TGTTGCTTTCACCGTTGGATTAGCTTTTGCGATTGCTGCAAGCGTGAATTTTCCTATTTTGCTTTTGTGTATTTATTGGA
AAAACCTCACCACAAAGGGTGCATTTTGGGGCGGACTTATAGGGCTTATAGTGGTGCTTACACTTGTAATTTTAAGTCCT
AGTATTTGGGTGAAAAGCTTTGGTTTTGAAAGTGCGATTTTCCCTTATGATCACCCTGCGATTTTTACTATGCCACTTAC
CTTTATCCTTATTTTTATTATTTCAAAGTTGGATAATTCTAAACGAGCACAAATTGATAGAGCAGGTTTTGAAGCACAGG
ATTTCCGTGCGCAAAGCGGTATAGGAGCAAGTGAGGCTGTAGCACATTAA

Upstream 100 bases:

>100_bases
TGCTTGAGCAATTAGAAAAAAATGGTGTGCTTGAAGCACTTAAAAGTGGCGAGATTCACTATAAAGAGCAAGCAGCTGAA
ACAGAAAAGGAGGAAAAGTA

Downstream 100 bases:

>100_bases
TTATAGAGTTAGAATCCCGCTACATAGTGCGGATTCTAGCAATTTCATCTCTTAATCTTGCCGCCTCTTCAAACTCAAGT
GCTTTAGCTGCTTGGTGCAT

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKSLFFSLSLLSVNSLFGASIDFGGAKSDINPIAIGMFLAFVLATLFITYLSNKKSQSASGFYTAGGNITGMQNGVAIAG
DYMSAASFLGITALVFTNGFDGLIYSIGFLAGWPIILFLIAEKFRNLGKFTFADITAYRLDAKPIRIISAISALSVIVFY
LIAQMVGAGQLIQVLFGLPYSVAVVLVGILMICYVVFGGMHATTWVQIIKAVLLLAGASFMAIMILYLTKFDLSYYFSQA
VSHHPKGESIMSPGGFLPDSISAVSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVFYATGLIGYFYILTFIIGFGAIA
LLLGNPDYTDANGAYNGVTNMVAVNLASVLGGDFFYGFICAVAFATILAVVSGLAITGAGAISHDLFVNVCKNGQCDPAL
EMRVTKIATICIGICAIALGIVFEKQNVAFTVGLAFAIAASVNFPILLLCIYWKNLTTKGAFWGGLIGLIVVLTLVILSP
SIWVKSFGFESAIFPYDHPAIFTMPLTFILIFIISKLDNSKRAQIDRAGFEAQDFRAQSGIGASEAVAH

Sequences:

>Translated_549_residues
MKSLFFSLSLLSVNSLFGASIDFGGAKSDINPIAIGMFLAFVLATLFITYLSNKKSQSASGFYTAGGNITGMQNGVAIAG
DYMSAASFLGITALVFTNGFDGLIYSIGFLAGWPIILFLIAEKFRNLGKFTFADITAYRLDAKPIRIISAISALSVIVFY
LIAQMVGAGQLIQVLFGLPYSVAVVLVGILMICYVVFGGMHATTWVQIIKAVLLLAGASFMAIMILYLTKFDLSYYFSQA
VSHHPKGESIMSPGGFLPDSISAVSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVFYATGLIGYFYILTFIIGFGAIA
LLLGNPDYTDANGAYNGVTNMVAVNLASVLGGDFFYGFICAVAFATILAVVSGLAITGAGAISHDLFVNVCKNGQCDPAL
EMRVTKIATICIGICAIALGIVFEKQNVAFTVGLAFAIAASVNFPILLLCIYWKNLTTKGAFWGGLIGLIVVLTLVILSP
SIWVKSFGFESAIFPYDHPAIFTMPLTFILIFIISKLDNSKRAQIDRAGFEAQDFRAQSGIGASEAVAH
>Mature_549_residues
MKSLFFSLSLLSVNSLFGASIDFGGAKSDINPIAIGMFLAFVLATLFITYLSNKKSQSASGFYTAGGNITGMQNGVAIAG
DYMSAASFLGITALVFTNGFDGLIYSIGFLAGWPIILFLIAEKFRNLGKFTFADITAYRLDAKPIRIISAISALSVIVFY
LIAQMVGAGQLIQVLFGLPYSVAVVLVGILMICYVVFGGMHATTWVQIIKAVLLLAGASFMAIMILYLTKFDLSYYFSQA
VSHHPKGESIMSPGGFLPDSISAVSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVFYATGLIGYFYILTFIIGFGAIA
LLLGNPDYTDANGAYNGVTNMVAVNLASVLGGDFFYGFICAVAFATILAVVSGLAITGAGAISHDLFVNVCKNGQCDPAL
EMRVTKIATICIGICAIALGIVFEKQNVAFTVGLAFAIAASVNFPILLLCIYWKNLTTKGAFWGGLIGLIVVLTLVILSP
SIWVKSFGFESAIFPYDHPAIFTMPLTFILIFIISKLDNSKRAQIDRAGFEAQDFRAQSGIGASEAVAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=468, Percent_Identity=22.8632478632479, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI1790503, Length=523, Percent_Identity=62.7151051625239, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI87082237, Length=436, Percent_Identity=21.7889908256881, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787251, Length=465, Percent_Identity=23.4408602150538, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58558; Mature: 58558

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLFFSLSLLSVNSLFGASIDFGGAKSDINPIAIGMFLAFVLATLFITYLSNKKSQSAS
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GFYTAGGNITGMQNGVAIAGDYMSAASFLGITALVFTNGFDGLIYSIGFLAGWPIILFLI
CEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AEKFRNLGKFTFADITAYRLDAKPIRIISAISALSVIVFYLIAQMVGAGQLIQVLFGLPY
HHHHHHCCCEEHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCH
SVAVVLVGILMICYVVFGGMHATTWVQIIKAVLLLAGASFMAIMILYLTKFDLSYYFSQA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VSHHPKGESIMSPGGFLPDSISAVSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVFYA
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TGLIGYFYILTFIIGFGAIALLLGNPDYTDANGAYNGVTNMVAVNLASVLGGDFFYGFIC
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFATILAVVSGLAITGAGAISHDLFVNVCKNGQCDPALEMRVTKIATICIGICAIALG
HHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IVFEKQNVAFTVGLAFAIAASVNFPILLLCIYWKNLTTKGAFWGGLIGLIVVLTLVILSP
HHEECCCCEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
SIWVKSFGFESAIFPYDHPAIFTMPLTFILIFIISKLDNSKRAQIDRAGFEAQDFRAQSG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHCC
IGASEAVAH
CCHHHHCCC
>Mature Secondary Structure
MKSLFFSLSLLSVNSLFGASIDFGGAKSDINPIAIGMFLAFVLATLFITYLSNKKSQSAS
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GFYTAGGNITGMQNGVAIAGDYMSAASFLGITALVFTNGFDGLIYSIGFLAGWPIILFLI
CEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AEKFRNLGKFTFADITAYRLDAKPIRIISAISALSVIVFYLIAQMVGAGQLIQVLFGLPY
HHHHHHCCCEEHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCH
SVAVVLVGILMICYVVFGGMHATTWVQIIKAVLLLAGASFMAIMILYLTKFDLSYYFSQA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VSHHPKGESIMSPGGFLPDSISAVSLGLALMFGTAGLPHILMRFFTVKDAKEARKSVFYA
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TGLIGYFYILTFIIGFGAIALLLGNPDYTDANGAYNGVTNMVAVNLASVLGGDFFYGFIC
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFATILAVVSGLAITGAGAISHDLFVNVCKNGQCDPALEMRVTKIATICIGICAIALG
HHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IVFEKQNVAFTVGLAFAIAASVNFPILLLCIYWKNLTTKGAFWGGLIGLIVVLTLVILSP
HHEECCCCEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
SIWVKSFGFESAIFPYDHPAIFTMPLTFILIFIISKLDNSKRAQIDRAGFEAQDFRAQSG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHCC
IGASEAVAH
CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA