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The map label for this gene is rpiB

Identifier: 32266867

GI number: 32266867

Start: 1322943

End: 1323386

Strand: Direct

Name: rpiB

Synonym: HH1368

Alternate gene names: 32266867

Gene position: 1322943-1323386 (Clockwise)

Preceding gene: 32266866

Following gene: 32266868

Centisome position: 73.53

GC content: 41.44

Gene sequence:

>444_bases
ATGACTTATGTTATAGGGACAGACCACGCAGGATTTAAGCTCAAGGAATTTACTATTTCATTTTTGCAGAAAAAAGGTTT
TGAAATCATAGATTTAGCACCTCAAACTAATCAAAGAGTAGATTATCCTGATTACGCAAAAAAAGTATGCGAGGCAGTGG
GTGAAGAAGTAAATCGCAGAGGCATTTTGATATGTGGAAGCGGAATTGGAATGAGCATTGCTGCTAATCGTTTTAAGCAT
ATTCGCGCTGCACTTTGTGTAGATGCTTATATGGCAAAAATGGCACGTGCCCATAATGACGCAAATGTGCTCTGTATGGG
AGAGCGCATTAGTGGCTTAGGTGAGGTGGAGTCAATCCTTGAAGCCTTTGTAAGCAGCGAATTTGAGGGTGAGCGGCATC
TTGTGCGTGTGGAAAAGCTAGGGAATCTAGGACAGATTCTATAA

Upstream 100 bases:

>100_bases
AAAGCAAGCGTTATACAATTCGTTGGGAGCGAATGTTTAAAACAACAGAGGGACTTGAAAAAGCTGCTCGAGAGGCAATG
CCAAAATGAAAAGAGATACA

Downstream 100 bases:

>100_bases
AGTTAAGGAGAAAGTATGGAAGGAAGTGTAGGAAATTTCATTGCAAAATGGTTTTTTTTAACGGGTTTTATTTTATTTGT
GCTTTATATGATTGTGCGGA

Product: ribose-5-phosphate isomerase B

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MTYVIGTDHAGFKLKEFTISFLQKKGFEIIDLAPQTNQRVDYPDYAKKVCEAVGEEVNRRGILICGSGIGMSIAANRFKH
IRAALCVDAYMAKMARAHNDANVLCMGERISGLGEVESILEAFVSSEFEGERHLVRVEKLGNLGQIL

Sequences:

>Translated_147_residues
MTYVIGTDHAGFKLKEFTISFLQKKGFEIIDLAPQTNQRVDYPDYAKKVCEAVGEEVNRRGILICGSGIGMSIAANRFKH
IRAALCVDAYMAKMARAHNDANVLCMGERISGLGEVESILEAFVSSEFEGERHLVRVEKLGNLGQIL
>Mature_146_residues
TYVIGTDHAGFKLKEFTISFLQKKGFEIIDLAPQTNQRVDYPDYAKKVCEAVGEEVNRRGILICGSGIGMSIAANRFKHI
RAALCVDAYMAKMARAHNDANVLCMGERISGLGEVESILEAFVSSEFEGERHLVRVEKLGNLGQIL

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=141, Percent_Identity=46.0992907801418, Blast_Score=129, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 16252; Mature: 16121

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYVIGTDHAGFKLKEFTISFLQKKGFEIIDLAPQTNQRVDYPDYAKKVCEAVGEEVNRR
CEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
GILICGSGIGMSIAANRFKHIRAALCVDAYMAKMARAHNDANVLCMGERISGLGEVESIL
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
EAFVSSEFEGERHLVRVEKLGNLGQIL
HHHHCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TYVIGTDHAGFKLKEFTISFLQKKGFEIIDLAPQTNQRVDYPDYAKKVCEAVGEEVNRR
EEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
GILICGSGIGMSIAANRFKHIRAALCVDAYMAKMARAHNDANVLCMGERISGLGEVESIL
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
EAFVSSEFEGERHLVRVEKLGNLGQIL
HHHHCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA