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The map label for this gene is mtnN [H]

Identifier: 32266782

GI number: 32266782

Start: 1244695

End: 1245393

Strand: Direct

Name: mtnN [H]

Synonym: HH1283

Alternate gene names: 32266782

Gene position: 1244695-1245393 (Clockwise)

Preceding gene: 161546625

Following gene: 32266783

Centisome position: 69.18

GC content: 37.2

Gene sequence:

>699_bases
ATGACACTTGGTATTATAGGGGCAATGATTGAAGAGATTACGCCTTTGCTTGAGCTCTTTGGTGATTATAAAGGCAGACA
AGTTGGCGGCAATACTTATTATGAAATTCAAAGAGGTGAACACAAAATTTTTGTTGCTTATAGCAAAATTGGCAAAGTTC
ATTCCGCTTTGACATCAAGCACAATGATTTTACATTTTGGTTGCGAGAAAATTATTTTTAGTGGTGTAGCAGGCGGTTTG
AGTGCAGATTTGAAAGTGGGTGATTTAATATTGGGGCAAAAACTTTGTCAATATGATGTAGATATTAGTGCATTTGGACA
CCCATTGGGTTTTATTCCTGAGAGCAAAATTTTTATAGAATCTGATGCTACACTCAATAGCATTGCACGTGAGATTGCAA
AGAAACAAGGCATTAAACTTAAAGAAGGCACTATTGCATCAGGTGATGCTTTTATAGCTGATTCTCAAAAAAAGCAGTGG
ATTATCCAGCATTTTGGAGCTGATGCAGTAGAAATGGAAGGAGCATCTGTAGCTGTAGTATGTGATTTGCTTGCTGTGCC
ATTTTGTATTTTACGCTCCATTAGTGATAGTGCTGATGGAAACGCCGATGTAAGCTTTGATGAATTTTTGGTAAGCTCGG
CAAAACGCAGTGCTGATTTTGTAATGATGATGTGTGAAATGATTTTAGCCCACAAATAA

Upstream 100 bases:

>100_bases
AGCGCTTAAGCACTCTACCTACTTGGAATATTGAGAATCTTGCAAGCTTGAAGGAATGTATTGATAGCATTAAGAGTGGA
GTTTAAATAAAGGAGTATCT

Downstream 100 bases:

>100_bases
AGGAGCATTTTATGAAAACAATTACTCTTTTGCGCCACGCCGATACAATAAGTAGGGAAGAATACCGACTCAACAATAAA
AAAGATAAAAGTGATATTTT

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTLGIIGAMIEEITPLLELFGDYKGRQVGGNTYYEIQRGEHKIFVAYSKIGKVHSALTSSTMILHFGCEKIIFSGVAGGL
SADLKVGDLILGQKLCQYDVDISAFGHPLGFIPESKIFIESDATLNSIAREIAKKQGIKLKEGTIASGDAFIADSQKKQW
IIQHFGADAVEMEGASVAVVCDLLAVPFCILRSISDSADGNADVSFDEFLVSSAKRSADFVMMMCEMILAHK

Sequences:

>Translated_232_residues
MTLGIIGAMIEEITPLLELFGDYKGRQVGGNTYYEIQRGEHKIFVAYSKIGKVHSALTSSTMILHFGCEKIIFSGVAGGL
SADLKVGDLILGQKLCQYDVDISAFGHPLGFIPESKIFIESDATLNSIAREIAKKQGIKLKEGTIASGDAFIADSQKKQW
IIQHFGADAVEMEGASVAVVCDLLAVPFCILRSISDSADGNADVSFDEFLVSSAKRSADFVMMMCEMILAHK
>Mature_231_residues
TLGIIGAMIEEITPLLELFGDYKGRQVGGNTYYEIQRGEHKIFVAYSKIGKVHSALTSSTMILHFGCEKIIFSGVAGGLS
ADLKVGDLILGQKLCQYDVDISAFGHPLGFIPESKIFIESDATLNSIAREIAKKQGIKLKEGTIASGDAFIADSQKKQWI
IQHFGADAVEMEGASVAVVCDLLAVPFCILRSISDSADGNADVSFDEFLVSSAKRSADFVMMMCEMILAHK

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=232, Percent_Identity=37.5, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25078; Mature: 24947

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGIIGAMIEEITPLLELFGDYKGRQVGGNTYYEIQRGEHKIFVAYSKIGKVHSALTSS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHC
TMILHFGCEKIIFSGVAGGLSADLKVGDLILGQKLCQYDVDISAFGHPLGFIPESKIFIE
EEEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEE
SDATLNSIAREIAKKQGIKLKEGTIASGDAFIADSQKKQWIIQHFGADAVEMEGASVAVV
CCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEECCCHHHHHHHHCCCCCEEECCCHHHHH
CDLLAVPFCILRSISDSADGNADVSFDEFLVSSAKRSADFVMMMCEMILAHK
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLGIIGAMIEEITPLLELFGDYKGRQVGGNTYYEIQRGEHKIFVAYSKIGKVHSALTSS
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHC
TMILHFGCEKIIFSGVAGGLSADLKVGDLILGQKLCQYDVDISAFGHPLGFIPESKIFIE
EEEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEE
SDATLNSIAREIAKKQGIKLKEGTIASGDAFIADSQKKQWIIQHFGADAVEMEGASVAVV
CCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEECCCHHHHHHHHCCCCCEEECCCHHHHH
CDLLAVPFCILRSISDSADGNADVSFDEFLVSSAKRSADFVMMMCEMILAHK
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]