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The map label for this gene is pgm

Identifier: 32266668

GI number: 32266668

Start: 1135976

End: 1137448

Strand: Direct

Name: pgm

Synonym: HH1169

Alternate gene names: 32266668

Gene position: 1135976-1137448 (Clockwise)

Preceding gene: 32266665

Following gene: 32266674

Centisome position: 63.14

GC content: 38.15

Gene sequence:

>1473_bases
ATGAAAACAATTCTTGTGATTACTGATGGCATAGGATATAGTGATAAAACGCAATATAACGCCTTTTATCACGCTAAAAA
GCCTACCTATGATTATTTATTCAAAAATGTGCCCTATGGTATGATTGATACTTTTGGTTTGAGCGTGGGATTACCTCAAG
GACAAATGGGAAATTCTGAAGTAGGGCATATGTGCATTGGTTCCGGGCGAGTATTATATCAAGATTTGGTTAGAATCTCG
CGTGCGATTGAGTATGATGAGATAAAAGATAATCCTGCTTTGGTTGAGGTTACGCAGCAGAGTGCAGTTGTGCATTTGTG
TGGATTACTAAGTGATGGCGGGGTGCATTCTCATATTGTGCATTTAAAGGCGCTTGCACAGATTCTAAGTACTCAAGGTA
AAAGGGTGTATTTACATCTTATTACTGATGGACGCGATGTTTTGCCTAAAAGTGCGCTTAATTATCTTGCAGATATAGAG
TCTATTTGCGAAGATAATGTAAGTATAGCAAGTGTATCTGGGCGTTTTTATGCGATGGATAGAGATAAAAGATGGGATAG
AGTGCAAAAGGCATATGAAAGTATAGCACTTGGCAAAAATCCTACAAATCTTTCTCCTAAAGAGTATATTCAATCTCAAT
ATGATGAAGGAATTTTTGATGAATTTCTTACTCCTGTGAGTTTTGGAGGGTTTCAAGGGATGAATGATGATGAAAGCTTT
GTGTTTGTGAATTTTCGATCTGATAGGGCACGTGAAATTGTTGATTGCTTAGGGAATCCACAATTTAAAGAGTTTAAGCG
GGAGCGATATGTAAAGCTTCATATTGCTACAATGACAGAATATGACGCAACATTCCCCTACCCTATTCTTTTTCCCAAGC
AAAATGTGCAAAATACTCTCGCCGAAGTAATTTCTTCACATCGTTTAAAGCAGTTTCATACCGCTGAAACTGAAAAATAT
GCTCACGTTACATTTTTCCTTAATGGAGGGCGCGAGGAAGCTTTTATAGGAGAGGAACGAGTGCTTATCCCTTCCCCTAA
TGTCAAAACTTATGATTTACAGCCTCAAATGAATGCTTCTGCAGTGGGTGATGCAGTAATAAAAGCTGTAGAGCAAGGAT
ATGATTTTGTGGTGGTAAATTTTGCAAATGGTGATATGGTCGGGCATACAGGGAATCTTGAAGCAGCAATTAAAGCAGTA
GAAGCGGTGGATAAGGAATTAGGTAGGATTGTAGAATCTGCTCAAAAACACCATTATGCTCTTTTTATCACGAGTGATCA
CGGAAATTGCGAAGAAATGAAAGATGAAAAAGGTAATATGCTCACAAATCATACCGTTGGACAAGTATGGTGTTTTGGTA
TGATTGAGGGAGTGAGTAAAATTGAGAATGGAGGATTGAATAACATCGCTCCAAGTGTCCTTAAGGCAATGAATCTGCCT
ATTCCACCTGAAATGGATAAGCCATTATTTTAA

Upstream 100 bases:

>100_bases
CCTTTTCCCCTTAACTTTTAAGGGAGTTAATTAGTTAATGAAAGGTTTTGGATTTTAGCTACAATTAGTTAATATGAAAG
ATTAAAATGAGGAGCATATT

Downstream 100 bases:

>100_bases
AAAAATTGGTTGCAATAAGTATAAAGCTTAGCTTTTATATTAAATGCTTAAATACACCGCAAGTGTGGTGATAATAAATC
CTGCACCTAAAACGCCAAAG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MKTILVITDGIGYSDKTQYNAFYHAKKPTYDYLFKNVPYGMIDTFGLSVGLPQGQMGNSEVGHMCIGSGRVLYQDLVRIS
RAIEYDEIKDNPALVEVTQQSAVVHLCGLLSDGGVHSHIVHLKALAQILSTQGKRVYLHLITDGRDVLPKSALNYLADIE
SICEDNVSIASVSGRFYAMDRDKRWDRVQKAYESIALGKNPTNLSPKEYIQSQYDEGIFDEFLTPVSFGGFQGMNDDESF
VFVNFRSDRAREIVDCLGNPQFKEFKRERYVKLHIATMTEYDATFPYPILFPKQNVQNTLAEVISSHRLKQFHTAETEKY
AHVTFFLNGGREEAFIGEERVLIPSPNVKTYDLQPQMNASAVGDAVIKAVEQGYDFVVVNFANGDMVGHTGNLEAAIKAV
EAVDKELGRIVESAQKHHYALFITSDHGNCEEMKDEKGNMLTNHTVGQVWCFGMIEGVSKIENGGLNNIAPSVLKAMNLP
IPPEMDKPLF

Sequences:

>Translated_490_residues
MKTILVITDGIGYSDKTQYNAFYHAKKPTYDYLFKNVPYGMIDTFGLSVGLPQGQMGNSEVGHMCIGSGRVLYQDLVRIS
RAIEYDEIKDNPALVEVTQQSAVVHLCGLLSDGGVHSHIVHLKALAQILSTQGKRVYLHLITDGRDVLPKSALNYLADIE
SICEDNVSIASVSGRFYAMDRDKRWDRVQKAYESIALGKNPTNLSPKEYIQSQYDEGIFDEFLTPVSFGGFQGMNDDESF
VFVNFRSDRAREIVDCLGNPQFKEFKRERYVKLHIATMTEYDATFPYPILFPKQNVQNTLAEVISSHRLKQFHTAETEKY
AHVTFFLNGGREEAFIGEERVLIPSPNVKTYDLQPQMNASAVGDAVIKAVEQGYDFVVVNFANGDMVGHTGNLEAAIKAV
EAVDKELGRIVESAQKHHYALFITSDHGNCEEMKDEKGNMLTNHTVGQVWCFGMIEGVSKIENGGLNNIAPSVLKAMNLP
IPPEMDKPLF
>Mature_490_residues
MKTILVITDGIGYSDKTQYNAFYHAKKPTYDYLFKNVPYGMIDTFGLSVGLPQGQMGNSEVGHMCIGSGRVLYQDLVRIS
RAIEYDEIKDNPALVEVTQQSAVVHLCGLLSDGGVHSHIVHLKALAQILSTQGKRVYLHLITDGRDVLPKSALNYLADIE
SICEDNVSIASVSGRFYAMDRDKRWDRVQKAYESIALGKNPTNLSPKEYIQSQYDEGIFDEFLTPVSFGGFQGMNDDESF
VFVNFRSDRAREIVDCLGNPQFKEFKRERYVKLHIATMTEYDATFPYPILFPKQNVQNTLAEVISSHRLKQFHTAETEKY
AHVTFFLNGGREEAFIGEERVLIPSPNVKTYDLQPQMNASAVGDAVIKAVEQGYDFVVVNFANGDMVGHTGNLEAAIKAV
EAVDKELGRIVESAQKHHYALFITSDHGNCEEMKDEKGNMLTNHTVGQVWCFGMIEGVSKIENGGLNNIAPSVLKAMNLP
IPPEMDKPLF

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=506, Percent_Identity=42.6877470355731, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI32564249, Length=502, Percent_Identity=43.2270916334661, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17507741, Length=502, Percent_Identity=43.2270916334661, Blast_Score=398, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_HELHP (Q7VGZ8)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860700.1
- ProteinModelPortal:   Q7VGZ8
- SMR:   Q7VGZ8
- GeneID:   1492857
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1169
- NMPDR:   fig|235279.1.peg.1169
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   HHEP235279:HH_1169-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 54777; Mature: 54777

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: ACT_SITE 59-59

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILVITDGIGYSDKTQYNAFYHAKKPTYDYLFKNVPYGMIDTFGLSVGLPQGQMGNSE
CCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCHHHHCCCEECCCCCCCCCCC
VGHMCIGSGRVLYQDLVRISRAIEYDEIKDNPALVEVTQQSAVVHLCGLLSDGGVHSHIV
CCCEEECCCHHHHHHHHHHHHHCCHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHH
HLKALAQILSTQGKRVYLHLITDGRDVLPKSALNYLADIESICEDNVSIASVSGRFYAMD
HHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEC
RDKRWDRVQKAYESIALGKNPTNLSPKEYIQSQYDEGIFDEFLTPVSFGGFQGMNDDESF
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCE
VFVNFRSDRAREIVDCLGNPQFKEFKRERYVKLHIATMTEYDATFPYPILFPKQNVQNTL
EEEEECCHHHHHHHHHHCCCCHHHHHHCCEEEEEEEEEECCCCCCCCEEECCCHHHHHHH
AEVISSHRLKQFHTAETEKYAHVTFFLNGGREEAFIGEERVLIPSPNVKTYDLQPQMNAS
HHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEECCCEEEECCCCCEEEECCCCCCHH
AVGDAVIKAVEQGYDFVVVNFANGDMVGHTGNLEAAIKAVEAVDKELGRIVESAQKHHYA
HHHHHHHHHHHCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LFITSDHGNCEEMKDEKGNMLTNHTVGQVWCFGMIEGVSKIENGGLNNIAPSVLKAMNLP
EEEECCCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
IPPEMDKPLF
CCCCCCCCCC
>Mature Secondary Structure
MKTILVITDGIGYSDKTQYNAFYHAKKPTYDYLFKNVPYGMIDTFGLSVGLPQGQMGNSE
CCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCHHHHCCCEECCCCCCCCCCC
VGHMCIGSGRVLYQDLVRISRAIEYDEIKDNPALVEVTQQSAVVHLCGLLSDGGVHSHIV
CCCEEECCCHHHHHHHHHHHHHCCHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHH
HLKALAQILSTQGKRVYLHLITDGRDVLPKSALNYLADIESICEDNVSIASVSGRFYAMD
HHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEC
RDKRWDRVQKAYESIALGKNPTNLSPKEYIQSQYDEGIFDEFLTPVSFGGFQGMNDDESF
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCE
VFVNFRSDRAREIVDCLGNPQFKEFKRERYVKLHIATMTEYDATFPYPILFPKQNVQNTL
EEEEECCHHHHHHHHHHCCCCHHHHHHCCEEEEEEEEEECCCCCCCCEEECCCHHHHHHH
AEVISSHRLKQFHTAETEKYAHVTFFLNGGREEAFIGEERVLIPSPNVKTYDLQPQMNAS
HHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEECCCEEEECCCCCEEEECCCCCCHH
AVGDAVIKAVEQGYDFVVVNFANGDMVGHTGNLEAAIKAVEAVDKELGRIVESAQKHHYA
HHHHHHHHHHHCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LFITSDHGNCEEMKDEKGNMLTNHTVGQVWCFGMIEGVSKIENGGLNNIAPSVLKAMNLP
EEEECCCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
IPPEMDKPLF
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954