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The map label for this gene is cdsA

Identifier: 32266022

GI number: 32266022

Start: 504844

End: 505698

Strand: Direct

Name: cdsA

Synonym: HH0523

Alternate gene names: 32266022

Gene position: 504844-505698 (Clockwise)

Preceding gene: 32266021

Following gene: 32266023

Centisome position: 28.06

GC content: 39.18

Gene sequence:

>855_bases
ATGGATACCAATGAGAAAGAATCTATAACATCTCAACAAAACACAAAAGAGCAGATAAAAGCGAAGTTTCTTGCTGATAA
GGCACGTTTTATCACTGCTGGTGTGCTTATAGTTGCACTTATTTTAATTTTAAGCATTGATTCAACCTTACTTACTTGTA
TCGTGCTTGCTATTATTTGCCTCATTGGTGTGCAAGAATCCCTTAAACTCTATGCTCTCCCACCTGCATTACATTATTAT
ATTGCTACAGCTTTTATTTGGGTGCTTGCATACTTTAATGAACGCATAATAGAATCTGCACTTTTTACTCTTGTGATTTA
CGCTTCCTATCTTGCTTATAGCAAAAAAATCTCGCCTAAAACCCTGCTTCCATTTATTTATCCTGTGTTGCCGTTTTTAA
GCATTTACGCACTCTATAAAGACGCCGGAGGAGCTGGAGTATGGGTGATTGTATGGCTTATTGTCATTGTAGCCCTCACT
GACACAGGAGCATATCTTGGAGGAAAAGCTTTTGGTAAAACGCCTTTTTGTCCTACGAGCCCCAAAAAAACCATTGAGGG
TGTTATTTGTGGGGTAATTTGTGGGGTAATTTGTGGCTCTATTGTGGGAATTGGCACTTGTGGAAACTTCTTATACTCAC
TTGGTATTACTTTTGTAGTCGCAATTTCTTCTGTCTTTGGCGATTTATTTGAGAGTTATCTCAAACGCGAAGCAGGTGTG
AAAGATAGTGGCTCTGTGTTGCCTGGACACGGTGGTGTGCTTGATAGGCTTGATGCTGTGCTTTTTGGTGCAATAGTAAT
GCACTTTTTACTTTTCTTTTTGCCCGGTTACAAAGACTTGGCAATTATGCTCTAA

Upstream 100 bases:

>100_bases
TGGATTGTGGTATAATGCTGGCTCATAGAATCTTACCTAACATTAAGATTCTATAAATTTATCATTAATTATATCATTAT
AACAATCCTAAGGAGTAAAA

Downstream 100 bases:

>100_bases
TTAATGATTTTACTTGGTAGCACAGGGAGCATTGGCACAAACGCCCTTGAAGTTGCCTCACATTTTGATATACCCATAGA
ATCTCTGTGTGCTGGGAAAA

Product: CDP-diglyceride synthetase CdsA

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MDTNEKESITSQQNTKEQIKAKFLADKARFITAGVLIVALILILSIDSTLLTCIVLAIICLIGVQESLKLYALPPALHYY
IATAFIWVLAYFNERIIESALFTLVIYASYLAYSKKISPKTLLPFIYPVLPFLSIYALYKDAGGAGVWVIVWLIVIVALT
DTGAYLGGKAFGKTPFCPTSPKKTIEGVICGVICGVICGSIVGIGTCGNFLYSLGITFVVAISSVFGDLFESYLKREAGV
KDSGSVLPGHGGVLDRLDAVLFGAIVMHFLLFFLPGYKDLAIML

Sequences:

>Translated_284_residues
MDTNEKESITSQQNTKEQIKAKFLADKARFITAGVLIVALILILSIDSTLLTCIVLAIICLIGVQESLKLYALPPALHYY
IATAFIWVLAYFNERIIESALFTLVIYASYLAYSKKISPKTLLPFIYPVLPFLSIYALYKDAGGAGVWVIVWLIVIVALT
DTGAYLGGKAFGKTPFCPTSPKKTIEGVICGVICGVICGSIVGIGTCGNFLYSLGITFVVAISSVFGDLFESYLKREAGV
KDSGSVLPGHGGVLDRLDAVLFGAIVMHFLLFFLPGYKDLAIML
>Mature_284_residues
MDTNEKESITSQQNTKEQIKAKFLADKARFITAGVLIVALILILSIDSTLLTCIVLAIICLIGVQESLKLYALPPALHYY
IATAFIWVLAYFNERIIESALFTLVIYASYLAYSKKISPKTLLPFIYPVLPFLSIYALYKDAGGAGVWVIVWLIVIVALT
DTGAYLGGKAFGKTPFCPTSPKKTIEGVICGVICGVICGSIVGIGTCGNFLYSLGITFVVAISSVFGDLFESYLKREAGV
KDSGSVLPGHGGVLDRLDAVLFGAIVMHFLLFFLPGYKDLAIML

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=145, Percent_Identity=37.9310344827586, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787677, Length=114, Percent_Identity=42.9824561403509, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30733; Mature: 30733

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNEKESITSQQNTKEQIKAKFLADKARFITAGVLIVALILILSIDSTLLTCIVLAIIC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LIGVQESLKLYALPPALHYYIATAFIWVLAYFNERIIESALFTLVIYASYLAYSKKISPK
HHCCHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TLLPFIYPVLPFLSIYALYKDAGGAGVWVIVWLIVIVALTDTGAYLGGKAFGKTPFCPTS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCC
PKKTIEGVICGVICGVICGSIVGIGTCGNFLYSLGITFVVAISSVFGDLFESYLKREAGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDSGSVLPGHGGVLDRLDAVLFGAIVMHFLLFFLPGYKDLAIML
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MDTNEKESITSQQNTKEQIKAKFLADKARFITAGVLIVALILILSIDSTLLTCIVLAIIC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LIGVQESLKLYALPPALHYYIATAFIWVLAYFNERIIESALFTLVIYASYLAYSKKISPK
HHCCHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TLLPFIYPVLPFLSIYALYKDAGGAGVWVIVWLIVIVALTDTGAYLGGKAFGKTPFCPTS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCC
PKKTIEGVICGVICGVICGSIVGIGTCGNFLYSLGITFVVAISSVFGDLFESYLKREAGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDSGSVLPGHGGVLDRLDAVLFGAIVMHFLLFFLPGYKDLAIML
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]