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The map label for this gene is trxB_1

Identifier: 32265985

GI number: 32265985

Start: 471235

End: 472170

Strand: Direct

Name: trxB_1

Synonym: HH0486

Alternate gene names: 32265985

Gene position: 471235-472170 (Clockwise)

Preceding gene: 32265984

Following gene: 32265986

Centisome position: 26.19

GC content: 39.64

Gene sequence:

>936_bases
ATGATTGATTTAGCAATTATCGGTGGTGGTCCAGCTGGACTAAGTGCAGGTTTATACGCAACAAGAGGCGGTATTAAAAA
TGTAGTGCTTTTTGAAAAAGGTATGCCCGGCGGACAGATTACAGGAAGTAGTGAAATAGAAAATTATCCGGGTGTAAAAG
ATATTGTAAGTGGTATGGAGTTTATGGAGCCTTGGCAAGAGCAATGCTTTCGCTTTGGATTAACTCATAAAATGAGTGAA
GTCAGCCAAATCACAAAGAAAAATGATATTTTTTACATTCATCAAACCGATGGAAGTATTGATGAAGCAAAAGCAGTAAT
TTTTTGCGCTGGTGGTAGCCCAAAAAGAGCAAATCTTAAGGGAGAAGATGAGTTTTGGGGTAGAGGTATAAGCACTTGTG
CTACTTGTGATGGATTTTTTTACAAAGACCAAGAGGTTATTGTGCTCGGCGGCGGTGATACAGCTCTTGAAGAAGCAGTA
TATCTTAGTCGGATTTGCTCTAAAGTGCATTTGGTGCATAGAAGAAATGAGTTCCGCGCTGCGCCCAGCACAATTGAACA
CGTAAAGAAAAATGATAAGATTCACATTGTTACTCCCGCAGTTGTTGAGGAAATCAAAGGCGATAAATCGGGTGTAACGA
GTGTGCTGATTAAACATACAGATTCAAATACAAATGAGGAAATCCCTGTTATGGGAATCTTTATTTTTGTAGGTTATAAT
GTCAATACAGCTACGCTCAAACAAGATGATGGCTCAATGCTTTGTGAATGCGATGAATATGGCAGTATCAAGGTAGATTT
ATCAATGAAAACAAGTGTAGAAGGTCTTTTTGCAGCTGGAGATGTCCGCACTCTTGCTCCCAAACAAGTTGTATGCGCAG
CTGGAGATGGTGCAACTGCGGCATTACAAGCTATTGCATATTTAGAACATAAGTAA

Upstream 100 bases:

>100_bases
AATTTCCTTACCTTATGAAACATTGCTTTTCCATTTACCTAGTTGTTGTTTTAGTTAATTATAGTAATGGAAAATTTTTA
TTATTTGTAAGGAGAAAAAT

Downstream 100 bases:

>100_bases
TATTATATATTTTATAGAATCTATTACATTTAAGGAGAATATATGCTAAAAGTAGGGATTTTTGGCGCTACGGGACGCGT
AGGAAAGCTACTTATTGAAG

Product: thioredoxin reductase TrxB

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIDLAIIGGGPAGLSAGLYATRGGIKNVVLFEKGMPGGQITGSSEIENYPGVKDIVSGMEFMEPWQEQCFRFGLTHKMSE
VSQITKKNDIFYIHQTDGSIDEAKAVIFCAGGSPKRANLKGEDEFWGRGISTCATCDGFFYKDQEVIVLGGGDTALEEAV
YLSRICSKVHLVHRRNEFRAAPSTIEHVKKNDKIHIVTPAVVEEIKGDKSGVTSVLIKHTDSNTNEEIPVMGIFIFVGYN
VNTATLKQDDGSMLCECDEYGSIKVDLSMKTSVEGLFAAGDVRTLAPKQVVCAAGDGATAALQAIAYLEHK

Sequences:

>Translated_311_residues
MIDLAIIGGGPAGLSAGLYATRGGIKNVVLFEKGMPGGQITGSSEIENYPGVKDIVSGMEFMEPWQEQCFRFGLTHKMSE
VSQITKKNDIFYIHQTDGSIDEAKAVIFCAGGSPKRANLKGEDEFWGRGISTCATCDGFFYKDQEVIVLGGGDTALEEAV
YLSRICSKVHLVHRRNEFRAAPSTIEHVKKNDKIHIVTPAVVEEIKGDKSGVTSVLIKHTDSNTNEEIPVMGIFIFVGYN
VNTATLKQDDGSMLCECDEYGSIKVDLSMKTSVEGLFAAGDVRTLAPKQVVCAAGDGATAALQAIAYLEHK
>Mature_311_residues
MIDLAIIGGGPAGLSAGLYATRGGIKNVVLFEKGMPGGQITGSSEIENYPGVKDIVSGMEFMEPWQEQCFRFGLTHKMSE
VSQITKKNDIFYIHQTDGSIDEAKAVIFCAGGSPKRANLKGEDEFWGRGISTCATCDGFFYKDQEVIVLGGGDTALEEAV
YLSRICSKVHLVHRRNEFRAAPSTIEHVKKNDKIHIVTPAVVEEIKGDKSGVTSVLIKHTDSNTNEEIPVMGIFIFVGYN
VNTATLKQDDGSMLCECDEYGSIKVDLSMKTSVEGLFAAGDVRTLAPKQVVCAAGDGATAALQAIAYLEHK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=38.0952380952381, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=30.3225806451613, Blast_Score=125, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=37.3417721518987, Blast_Score=192, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=36.7088607594937, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33552; Mature: 33552

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLAIIGGGPAGLSAGLYATRGGIKNVVLFEKGMPGGQITGSSEIENYPGVKDIVSGME
CEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
FMEPWQEQCFRFGLTHKMSEVSQITKKNDIFYIHQTDGSIDEAKAVIFCAGGSPKRANLK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCC
GEDEFWGRGISTCATCDGFFYKDQEVIVLGGGDTALEEAVYLSRICSKVHLVHRRNEFRA
CCHHHHCCCCCHHCCCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCC
APSTIEHVKKNDKIHIVTPAVVEEIKGDKSGVTSVLIKHTDSNTNEEIPVMGIFIFVGYN
CCHHHHHHHCCCCEEEECHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEECC
VNTATLKQDDGSMLCECDEYGSIKVDLSMKTSVEGLFAAGDVRTLAPKQVVCAAGDGATA
CCEEEEECCCCCEEEEECCCCCEEEEEEECCCCCEEEECCCCEECCCCEEEEECCCCHHH
ALQAIAYLEHK
HHHHHHHHCCC
>Mature Secondary Structure
MIDLAIIGGGPAGLSAGLYATRGGIKNVVLFEKGMPGGQITGSSEIENYPGVKDIVSGME
CEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
FMEPWQEQCFRFGLTHKMSEVSQITKKNDIFYIHQTDGSIDEAKAVIFCAGGSPKRANLK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCC
GEDEFWGRGISTCATCDGFFYKDQEVIVLGGGDTALEEAVYLSRICSKVHLVHRRNEFRA
CCHHHHCCCCCHHCCCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCC
APSTIEHVKKNDKIHIVTPAVVEEIKGDKSGVTSVLIKHTDSNTNEEIPVMGIFIFVGYN
CCHHHHHHHCCCCEEEECHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEECC
VNTATLKQDDGSMLCECDEYGSIKVDLSMKTSVEGLFAAGDVRTLAPKQVVCAAGDGATA
CCEEEEECCCCCEEEEECCCCCEEEEEEECCCCCEEEECCCCEECCCCEEEEECCCCHHH
ALQAIAYLEHK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]