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The map label for this gene is infC

Identifier: 32265942

GI number: 32265942

Start: 424120

End: 424644

Strand: Direct

Name: infC

Synonym: HH0443

Alternate gene names: 32265942

Gene position: 424120-424644 (Clockwise)

Preceding gene: 32265941

Following gene: 161546632

Centisome position: 23.57

GC content: 36.57

Gene sequence:

>525_bases
TTGAGCAAAGAAGAAGTATTACTCAATGAGGAGATAGATTTTAAGGAAGTGCGCTGCGTAAGTGATAATGGCGAGGTATA
CGGCATTATTTCATCTAAAGAAGCCTTAAATCTTGCCCATAAAGCTGGGCTTGATTTGGTGTTGATTTCACCTAATGCCA
AACCACCTGTGTGCAAAATAATGGATTATGGTAAATTTCGTTACCAAGCTGAAAAAAAGCAAAAAGAAGCACGCAAAAAG
CAAAAACAAATTGAGATTAAAGAGATTAAACTTTCAACTCAAATTGCCCAAAATGATATTAACTACAAAGTAAAGCACGC
GATTGAATTTTTAGAATCTGGTAAGCACGTAAAGTTTAAAGTATTTCTCAAACAACGTGAACTCAATATCCCCGATGCGG
GAATGGATACACTTGGCAAAGTCGCGGTTATGCTTGAGGATATTGCAATCGCAGAAAAAGAGCCAAAACTAGAGGGAAAA
CACCTTAATGTGCTCTATGTGCCAAAGAAAAAAGAAAAACACTAA

Upstream 100 bases:

>100_bases
AAATCCTTGCAATCCGAGATAGGCGGGAGAAATCACAATATGAGCTCCCTGAAGAAGCATTCATTGCTACATTGAAAACA
AAAATAGGAGAGGTTAGTTT

Downstream 100 bases:

>100_bases
ATCTTATGAAAGGAGAGAGATAATGCCAAAGATGAAAACAAATCGTGGTGCAGCAAAGCGTTTTAAGCTTAAAAAAAATG
CAATCAAACGTGGTAGTGCA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSKEEVLLNEEIDFKEVRCVSDNGEVYGIISSKEALNLAHKAGLDLVLISPNAKPPVCKIMDYGKFRYQAEKKQKEARKK
QKQIEIKEIKLSTQIAQNDINYKVKHAIEFLESGKHVKFKVFLKQRELNIPDAGMDTLGKVAVMLEDIAIAEKEPKLEGK
HLNVLYVPKKKEKH

Sequences:

>Translated_174_residues
MSKEEVLLNEEIDFKEVRCVSDNGEVYGIISSKEALNLAHKAGLDLVLISPNAKPPVCKIMDYGKFRYQAEKKQKEARKK
QKQIEIKEIKLSTQIAQNDINYKVKHAIEFLESGKHVKFKVFLKQRELNIPDAGMDTLGKVAVMLEDIAIAEKEPKLEGK
HLNVLYVPKKKEKH
>Mature_173_residues
SKEEVLLNEEIDFKEVRCVSDNGEVYGIISSKEALNLAHKAGLDLVLISPNAKPPVCKIMDYGKFRYQAEKKQKEARKKQ
KQIEIKEIKLSTQIAQNDINYKVKHAIEFLESGKHVKFKVFLKQRELNIPDAGMDTLGKVAVMLEDIAIAEKEPKLEGKH
LNVLYVPKKKEKH

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=44.578313253012, Blast_Score=122, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_HELHP (Q7VJ08)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859974.1
- ProteinModelPortal:   Q7VJ08
- GeneID:   1493497
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0443
- NMPDR:   fig|235279.1.peg.443
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   HHEP235279:HH_0443-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 19900; Mature: 19768

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEEVLLNEEIDFKEVRCVSDNGEVYGIISSKEALNLAHKAGLDLVLISPNAKPPVCKI
CCCCCEEECCCCCHHHEEEECCCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCEEEE
MDYGKFRYQAEKKQKEARKKQKQIEIKEIKLSTQIAQNDINYKVKHAIEFLESGKHVKFK
ECCCCHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
VFLKQRELNIPDAGMDTLGKVAVMLEDIAIAEKEPKLEGKHLNVLYVPKKKEKH
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
SKEEVLLNEEIDFKEVRCVSDNGEVYGIISSKEALNLAHKAGLDLVLISPNAKPPVCKI
CCCCEEECCCCCHHHEEEECCCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCEEEE
MDYGKFRYQAEKKQKEARKKQKQIEIKEIKLSTQIAQNDINYKVKHAIEFLESGKHVKFK
ECCCCHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
VFLKQRELNIPDAGMDTLGKVAVMLEDIAIAEKEPKLEGKHLNVLYVPKKKEKH
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954