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The map label for this gene is atpC

Identifier: 32265929

GI number: 32265929

Start: 414278

End: 414673

Strand: Direct

Name: atpC

Synonym: HH0430

Alternate gene names: 32265929

Gene position: 414278-414673 (Clockwise)

Preceding gene: 32265928

Following gene: 32265930

Centisome position: 23.03

GC content: 37.12

Gene sequence:

>396_bases
ATGGAAAATCTCACACTAAGTATTGTAACTCCTTATGGGAGCATCTATAATGGTGAAGTAAAATATGTTGTTATACCCGG
TAGTGAGGGAGAGTTTGGTGTTTTTCCAGGACATTGCAATCTTCTTTCGCTTCTTAAAGTTGGTGTTATTGAATTTGAAA
ACTTGGAAGGTAATAAAGGACTTGTAGCAATAAACTGGGGACACGCTCAAATATCAGATACTGATGTGAATATTATTGCT
GATGGTGCAGTTGCTATTGCAGGTAATACCGAATCCGAAATTGTTGCGGCCATCAGTGATGCCAAAACTCTTCTTAAAGA
AGCTTCAGATGATAGTGCTTTATTTGGTATGGTAGTTTCTCGTGTTGAAAGTGATTACAAGAACTTCATTAAGTAG

Upstream 100 bases:

>100_bases
GTAAATACGATGATATTCCTGAAAATGCTTTTTATTTGGTAGGCAATATCCAAGAAGCATTAGAAAAAGCTCAAAAGCTT
AAAAATGCCTAGGTGATAAT

Downstream 100 bases:

>100_bases
AATCTAGCAATGGGAACACTTAAAACTTTCTTTGAAGAAAGCACATTAACAACTATTATTGTGCTTTCTTGGCTCTCTCT
GTATTTTCTTATTACATTTT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MENLTLSIVTPYGSIYNGEVKYVVIPGSEGEFGVFPGHCNLLSLLKVGVIEFENLEGNKGLVAINWGHAQISDTDVNIIA
DGAVAIAGNTESEIVAAISDAKTLLKEASDDSALFGMVVSRVESDYKNFIK

Sequences:

>Translated_131_residues
MENLTLSIVTPYGSIYNGEVKYVVIPGSEGEFGVFPGHCNLLSLLKVGVIEFENLEGNKGLVAINWGHAQISDTDVNIIA
DGAVAIAGNTESEIVAAISDAKTLLKEASDDSALFGMVVSRVESDYKNFIK
>Mature_131_residues
MENLTLSIVTPYGSIYNGEVKYVVIPGSEGEFGVFPGHCNLLSLLKVGVIEFENLEGNKGLVAINWGHAQISDTDVNIIA
DGAVAIAGNTESEIVAAISDAKTLLKEASDDSALFGMVVSRVESDYKNFIK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_HELHP (Q7VJ20)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859961.1
- ProteinModelPortal:   Q7VJ20
- SMR:   Q7VJ20
- GeneID:   1493484
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0430
- NMPDR:   fig|235279.1.peg.430
- HOGENOM:   HBG663981
- OMA:   KKESDDR
- ProtClustDB:   PRK00571
- BioCyc:   HHEP235279:HH_0430-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020546
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF02823 ATP-synt_DE_N; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 13936; Mature: 13936

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLTLSIVTPYGSIYNGEVKYVVIPGSEGEFGVFPGHCNLLSLLKVGVIEFENLEGNKG
CCCEEEEEECCCCCEECCEEEEEEEECCCCCEEEECCCCHHHHHHHHCEEEEECCCCCCC
LVAINWGHAQISDTDVNIIADGAVAIAGNTESEIVAAISDAKTLLKEASDDSALFGMVVS
EEEEECCCEEECCCCEEEEECCEEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
RVESDYKNFIK
HHHHHHHHHCC
>Mature Secondary Structure
MENLTLSIVTPYGSIYNGEVKYVVIPGSEGEFGVFPGHCNLLSLLKVGVIEFENLEGNKG
CCCEEEEEECCCCCEECCEEEEEEEECCCCCEEEECCCCHHHHHHHHCEEEEECCCCCCC
LVAINWGHAQISDTDVNIIADGAVAIAGNTESEIVAAISDAKTLLKEASDDSALFGMVVS
EEEEECCCEEECCCCEEEEECCEEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
RVESDYKNFIK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12810954