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The map label for this gene is atpD

Identifier: 32265928

GI number: 32265928

Start: 412869

End: 414269

Strand: Direct

Name: atpD

Synonym: HH0429

Alternate gene names: 32265928

Gene position: 412869-414269 (Clockwise)

Preceding gene: 32265927

Following gene: 32265929

Centisome position: 22.95

GC content: 38.62

Gene sequence:

>1401_bases
ATGCAAGGTAAAATTACACAAGTAATGGGTCCAGTGGTAGATGTTGAGTTTAGCTCCTATTTGCCAATGATTAATGAGGC
TATTGATGTTAATTTTGACATAGAGGGACGAAAAAATAATCTCGTTCTAGAGGTTGCGGCACATCTTGGAGATAATCGTG
TAAGAACAATTGCTATGGATATGACAGAAGGGCTTATACGCGGACAAGAAGTTAAAGCACGTGGCAAACCTATTGAAGTG
CCTGTAGGGGAAGCTGTCTTGGGAAGAATTTTTAATGTTACTGGTGATGTAATTGATGGAGGTAAACCTCTTGAAAGTGA
CCTTAAGTGGCCTATTCACCGAGAAGCTCCAAGCTTTGAGAATCAAAGTACAAGAACAGAAATGTTTGAAACAGGTATTA
AAGTCGTTGATCTTATAGCTCCTTATTCTAAAGGTGGAAAAGTTGGATTATTTGGTGGTGCAGGTGTGGGTAAAACGGTT
GTTATTATGGAACTCATTCATAATGTTGCCTATAAGCATAGTGGTTATTCTGTTTTTGCCGGTGTAGGGGAACGTACAAG
AGAAGGAAATGATTTATACCACGAAATGAAAGAAGGGGGGGTATTAGACAAAGTTGCTCTCTGCTATGGGCAAATGAATG
AACCACCGGGAGCGAGAAATCGTATTGCTTTTACAGGTTTGACAATGGCGGAATATTTCCGTGATGAAAAAGGACTCGAT
GTACTTATGTTTATTGATAACATTTTCAGATATGCACAATCTGGTTCTGAAATGTCAGCACTTCTTGGGCGTATTCCTTC
AGCAGTAGGTTATCAACCTACTCTTGCAGGTGAAATGGGTAAACTTCAAGAACGTATTACTTCAACCAAAAAAGGTTCAA
TTACTTCTGTTCAAGCTGTATATGTGCCAGCAGATGACTTAACTGACCCAGCTCCAGCATCTGTATTTGCACACCTTGAT
GCAACAACAGTGCTTGATAGAAAAATTTCTGAAAAGGGAATCTACCCTGCAGTAGATCCTCTTGGCTCAACATCAAGAAT
CCTTGACCCTCAAATTGTAGGAGAAGAACATCATAAAGTTGCAACAGGTGTACAACAAGTGCTACAAAAATACAAAGACT
TACAAGATATTATCGCTATTTTAGGTATGGACGAGCTTTCGGAAGAAGATAAACAAGTAGTTGCCCGAGCAAGAAAAATT
GAAAGATTCCTTTCTCAGCCTTTCTTTGTTGCAGAAATTTTTACAGGTAGTCCAGGCAAATATGTAACGCTTGAGGAAAC
ACTTGAAGGCTTTAAAGGTATTTTAGAAGGTAAATACGATGATATTCCTGAAAATGCTTTTTATTTGGTAGGCAATATCC
AAGAAGCATTAGAAAAAGCTCAAAAGCTTAAAAATGCCTAG

Upstream 100 bases:

>100_bases
AATCTCTCTTAATAAAGCTCGGCAAGAGGCAATCACAACAGAACTTGTTGAGATCAATGCTGGTGCTGAAGCGATAAAAT
AAATTTACAAAGGAGAATAA

Downstream 100 bases:

>100_bases
GTGATAATATGGAAAATCTCACACTAAGTATTGTAACTCCTTATGGGAGCATCTATAATGGTGAAGTAAAATATGTTGTT
ATACCCGGTAGTGAGGGAGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MQGKITQVMGPVVDVEFSSYLPMINEAIDVNFDIEGRKNNLVLEVAAHLGDNRVRTIAMDMTEGLIRGQEVKARGKPIEV
PVGEAVLGRIFNVTGDVIDGGKPLESDLKWPIHREAPSFENQSTRTEMFETGIKVVDLIAPYSKGGKVGLFGGAGVGKTV
VIMELIHNVAYKHSGYSVFAGVGERTREGNDLYHEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
VLMFIDNIFRYAQSGSEMSALLGRIPSAVGYQPTLAGEMGKLQERITSTKKGSITSVQAVYVPADDLTDPAPASVFAHLD
ATTVLDRKISEKGIYPAVDPLGSTSRILDPQIVGEEHHKVATGVQQVLQKYKDLQDIIAILGMDELSEEDKQVVARARKI
ERFLSQPFFVAEIFTGSPGKYVTLEETLEGFKGILEGKYDDIPENAFYLVGNIQEALEKAQKLKNA

Sequences:

>Translated_466_residues
MQGKITQVMGPVVDVEFSSYLPMINEAIDVNFDIEGRKNNLVLEVAAHLGDNRVRTIAMDMTEGLIRGQEVKARGKPIEV
PVGEAVLGRIFNVTGDVIDGGKPLESDLKWPIHREAPSFENQSTRTEMFETGIKVVDLIAPYSKGGKVGLFGGAGVGKTV
VIMELIHNVAYKHSGYSVFAGVGERTREGNDLYHEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
VLMFIDNIFRYAQSGSEMSALLGRIPSAVGYQPTLAGEMGKLQERITSTKKGSITSVQAVYVPADDLTDPAPASVFAHLD
ATTVLDRKISEKGIYPAVDPLGSTSRILDPQIVGEEHHKVATGVQQVLQKYKDLQDIIAILGMDELSEEDKQVVARARKI
ERFLSQPFFVAEIFTGSPGKYVTLEETLEGFKGILEGKYDDIPENAFYLVGNIQEALEKAQKLKNA
>Mature_466_residues
MQGKITQVMGPVVDVEFSSYLPMINEAIDVNFDIEGRKNNLVLEVAAHLGDNRVRTIAMDMTEGLIRGQEVKARGKPIEV
PVGEAVLGRIFNVTGDVIDGGKPLESDLKWPIHREAPSFENQSTRTEMFETGIKVVDLIAPYSKGGKVGLFGGAGVGKTV
VIMELIHNVAYKHSGYSVFAGVGERTREGNDLYHEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
VLMFIDNIFRYAQSGSEMSALLGRIPSAVGYQPTLAGEMGKLQERITSTKKGSITSVQAVYVPADDLTDPAPASVFAHLD
ATTVLDRKISEKGIYPAVDPLGSTSRILDPQIVGEEHHKVATGVQQVLQKYKDLQDIIAILGMDELSEEDKQVVARARKI
ERFLSQPFFVAEIFTGSPGKYVTLEETLEGFKGILEGKYDDIPENAFYLVGNIQEALEKAQKLKNA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=467, Percent_Identity=69.3790149892934, Blast_Score=649, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=28.3489096573209, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI19913428, Length=421, Percent_Identity=23.7529691211401, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913426, Length=424, Percent_Identity=23.8207547169811, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI50345984, Length=377, Percent_Identity=25.4641909814324, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4757810, Length=377, Percent_Identity=25.4641909814324, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1790170, Length=462, Percent_Identity=67.965367965368, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=377, Percent_Identity=28.1167108753316, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1790172, Length=391, Percent_Identity=25.3196930946292, Blast_Score=118, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=467, Percent_Identity=67.237687366167, Blast_Score=631, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=321, Percent_Identity=29.2834890965732, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17570191, Length=422, Percent_Identity=24.1706161137441, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=424, Percent_Identity=24.5283018867925, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988063, Length=354, Percent_Identity=24.5762711864407, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=354, Percent_Identity=24.2937853107345, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988074, Length=329, Percent_Identity=23.4042553191489, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=68.2505399568035, Blast_Score=634, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=424, Percent_Identity=25.9433962264151, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319370, Length=353, Percent_Identity=26.0623229461756, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=26.1802575107296, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24638766, Length=468, Percent_Identity=69.2307692307692, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=468, Percent_Identity=66.2393162393162, Blast_Score=611, Evalue=1e-175,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=28.3489096573209, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI20129479, Length=332, Percent_Identity=28.6144578313253, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583988, Length=324, Percent_Identity=29.0123456790123, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24583986, Length=324, Percent_Identity=29.0123456790123, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24583984, Length=324, Percent_Identity=29.0123456790123, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281361666, Length=351, Percent_Identity=25.6410256410256, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646341, Length=351, Percent_Identity=25.6410256410256, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136796, Length=351, Percent_Identity=25.6410256410256, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24658560, Length=355, Percent_Identity=24.5070422535211, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24638768, Length=94, Percent_Identity=57.4468085106383, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_HELHP (Q7VJ21)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859960.1
- ProteinModelPortal:   Q7VJ21
- SMR:   Q7VJ21
- GeneID:   1493483
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0429
- NMPDR:   fig|235279.1.peg.429
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   HHEP235279:HH_0429-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51046; Mature: 51046

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGKITQVMGPVVDVEFSSYLPMINEAIDVNFDIEGRKNNLVLEVAAHLGDNRVRTIAMD
CCCCHHHHHCCCEEECHHHHHHHHHHHEECEEEECCCCCCEEEEEEHHCCCCCEEEEEHH
MTEGLIRGQEVKARGKPIEVPVGEAVLGRIFNVTGDVIDGGKPLESDLKWPIHREAPSFE
HHHHHHCCCHHHCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCC
NQSTRTEMFETGIKVVDLIAPYSKGGKVGLFGGAGVGKTVVIMELIHNVAYKHSGYSVFA
CCHHHHHHHHHCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEE
GVGERTREGNDLYHEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCE
VLMFIDNIFRYAQSGSEMSALLGRIPSAVGYQPTLAGEMGKLQERITSTKKGSITSVQAV
EHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
YVPADDLTDPAPASVFAHLDATTVLDRKISEKGIYPAVDPLGSTSRILDPQIVGEEHHKV
EECCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHH
ATGVQQVLQKYKDLQDIIAILGMDELSEEDKQVVARARKIERFLSQPFFVAEIFTGSPGK
HHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
YVTLEETLEGFKGILEGKYDDIPENAFYLVGNIQEALEKAQKLKNA
EEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGKITQVMGPVVDVEFSSYLPMINEAIDVNFDIEGRKNNLVLEVAAHLGDNRVRTIAMD
CCCCHHHHHCCCEEECHHHHHHHHHHHEECEEEECCCCCCEEEEEEHHCCCCCEEEEEHH
MTEGLIRGQEVKARGKPIEVPVGEAVLGRIFNVTGDVIDGGKPLESDLKWPIHREAPSFE
HHHHHHCCCHHHCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCC
NQSTRTEMFETGIKVVDLIAPYSKGGKVGLFGGAGVGKTVVIMELIHNVAYKHSGYSVFA
CCHHHHHHHHHCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEE
GVGERTREGNDLYHEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLD
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCE
VLMFIDNIFRYAQSGSEMSALLGRIPSAVGYQPTLAGEMGKLQERITSTKKGSITSVQAV
EHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
YVPADDLTDPAPASVFAHLDATTVLDRKISEKGIYPAVDPLGSTSRILDPQIVGEEHHKV
EECCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHH
ATGVQQVLQKYKDLQDIIAILGMDELSEEDKQVVARARKIERFLSQPFFVAEIFTGSPGK
HHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
YVTLEETLEGFKGILEGKYDDIPENAFYLVGNIQEALEKAQKLKNA
EEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12810954