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The map label for this gene is gidA

Identifier: 32265512

GI number: 32265512

Start: 11394

End: 13283

Strand: Direct

Name: gidA

Synonym: HH0013

Alternate gene names: 32265512

Gene position: 11394-13283 (Clockwise)

Preceding gene: 32265510

Following gene: 32265513

Centisome position: 0.63

GC content: 37.04

Gene sequence:

>1890_bases
TTGGTTATTGGAGGTGGACACGCAGGAGTTGAAGCAAGCATTGTAAGTGCAAAAATGGGTGCAAAAACACATCTTATCAC
ACTTCTAATTCAAAATATTGCCTTAGCGAGTTGTAATCCAGCCGTAGGGGGACTAGGAAAAGGACATCTTGTTAAGGAAA
TTGACGCACTTGGTGGCGTTATGGGTGTAATCACAGATAAATGCGGCATACAATTTAGAATCTTAAATGCCTCTAAGGGA
CCAGCTGTGCGTGGCACAAGAGCACAAATAGATATGGATAGATATAGTATTTTTGCAAAAGAAATAGCTCTTAATACTCC
TAATCTAACAATCTCTCAAGAAAGCGTAGAATCTTTAATTTATGAGCAAGATTCTAAAGGACGCTATATTGTAAAAGGCG
TAACAACTAACATTGGAAAAACTTATTTTGCAAAAAAAGTTATCCTTACCACAGGCACTTTTTTACGAGGGCTTGTGCAT
ATCGGAGAAACAAAATTACAAAATGGACGTTTTGGTGAAATGAGTCCACAGAATCTTAGCAATTCACTCCAAGATATGGG
CTTAACTCTTGGGCGATTAAAAACAGGGACTTGCGCAAGAATTGATGGACGAAGCATTGATTTTTCCGCTCTTGAAATAC
ATAATGGAGATGAGAAACCACCTCATTTTAGCTATAAAACGATAAATTTTTCACCCACACAACTTCCTTGTTTTGTAACT
TATACCAATGAAAACACTCATAAAATTATCCGCGATAACTTTCATCGCGCACCACTTTTTACAGGGCAAATTGAGGGTGT
AGGACCCCGTTATTGTCCAAGTATTGAAGATAAAGTCAATCGCTTTGCCGATAAAAGTCGTCATCAACTCTTTTTAGAGC
CGCAAACACAAGAGGCTGTGGAATACTATATCAATGGACTTTCTACTTCACTACCTATTGATGTGCAAGAAGCGGTGATT
CATAGCATTAAAGGACTAGAAAATGCACATATAACGCGCTATGGTTATGCTATTGAATATGATTATGTTGAACCTACTGA
GCTTTATCATACACTTGAGACAAAAAAATGCGCAAATCTCTTCCTCGCAGGACAAATTAATGGCACTACGGGCTATGAAG
AAGCTGCTGCACAAGGCATTATGGCAGGGATTAATGCTACACTTTCTTTGCAAAATAAATCTTTTACTCTTGCGCGAAAT
GAGGCTTATATTGGCGTAATGATTGATGATTTAGTAACAAAAGGCACAAAAGAACCCTATCGTGTTTTTACTTCACGTGC
CGAATATCGTCTTTTGCTGCGAGAGGATAATGCGTATTTGCGTCTTGGAACTTATGCATATAAATTTGGCTTAATAGATA
AGGTGCGTTATACACAAATAATGGCAGATAAAACTCATATTGAGCACACAATAAATTATTTACAAAATCATCATATCACA
CCCTCATCAAGCAATCTCACTATGCTTGCCTCATTAGGGCTTCCACCCATTAGCGATAAAGCACTCCTTATTCATATTGT
TGGTCGTGAAGAATTGGATTGTGCTCTTCTCCGCACTCTTTTGACGCATTTAGGAATAACAGATGTAGAATCTATGAGTG
ATTTAGCTATTGAACAGATTTTTATAGAATCTAAATATTTTGACTATATTCAAAAACAAAAGCAGCAAATAGGACAAATG
AGACAAATGCTACAAGTGGAAATTCCACGAGATTTTATCTTTGATAATATCCCCGGACTAAGCCTTGAAGTGATTGAAAA
ACTTAAAAAATTCACCCCTAAAAGCTTATTTGAGGCAAATGAAATTAGCGGAATCACGCCTGCAAGCATTGATGTCCTGC
ATTTATACATCCATTTGCACCATAAAAAAAAGTCTCAAATTTTGGTATAA

Upstream 100 bases:

>100_bases
CTAAAAATCCACTTTATATAAGCGTGAGGGTAGCAAAAATAATCAAATAAGAGTAAAATGCCATAAAATTTTTGAAGGAT
AATTTATGCAATATGATATT

Downstream 100 bases:

>100_bases
TATTACATTTTATAAGGAGTATCAATGAAACATATTCATAAAATTAAAAATTACGCTATGGTTGGAGGATTAGGAGTTAT
GGCTGTTTTCGCACTCAATG

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MVIGGGHAGVEASIVSAKMGAKTHLITLLIQNIALASCNPAVGGLGKGHLVKEIDALGGVMGVITDKCGIQFRILNASKG
PAVRGTRAQIDMDRYSIFAKEIALNTPNLTISQESVESLIYEQDSKGRYIVKGVTTNIGKTYFAKKVILTTGTFLRGLVH
IGETKLQNGRFGEMSPQNLSNSLQDMGLTLGRLKTGTCARIDGRSIDFSALEIHNGDEKPPHFSYKTINFSPTQLPCFVT
YTNENTHKIIRDNFHRAPLFTGQIEGVGPRYCPSIEDKVNRFADKSRHQLFLEPQTQEAVEYYINGLSTSLPIDVQEAVI
HSIKGLENAHITRYGYAIEYDYVEPTELYHTLETKKCANLFLAGQINGTTGYEEAAAQGIMAGINATLSLQNKSFTLARN
EAYIGVMIDDLVTKGTKEPYRVFTSRAEYRLLLREDNAYLRLGTYAYKFGLIDKVRYTQIMADKTHIEHTINYLQNHHIT
PSSSNLTMLASLGLPPISDKALLIHIVGREELDCALLRTLLTHLGITDVESMSDLAIEQIFIESKYFDYIQKQKQQIGQM
RQMLQVEIPRDFIFDNIPGLSLEVIEKLKKFTPKSLFEANEISGITPASIDVLHLYIHLHHKKKSQILV

Sequences:

>Translated_629_residues
MVIGGGHAGVEASIVSAKMGAKTHLITLLIQNIALASCNPAVGGLGKGHLVKEIDALGGVMGVITDKCGIQFRILNASKG
PAVRGTRAQIDMDRYSIFAKEIALNTPNLTISQESVESLIYEQDSKGRYIVKGVTTNIGKTYFAKKVILTTGTFLRGLVH
IGETKLQNGRFGEMSPQNLSNSLQDMGLTLGRLKTGTCARIDGRSIDFSALEIHNGDEKPPHFSYKTINFSPTQLPCFVT
YTNENTHKIIRDNFHRAPLFTGQIEGVGPRYCPSIEDKVNRFADKSRHQLFLEPQTQEAVEYYINGLSTSLPIDVQEAVI
HSIKGLENAHITRYGYAIEYDYVEPTELYHTLETKKCANLFLAGQINGTTGYEEAAAQGIMAGINATLSLQNKSFTLARN
EAYIGVMIDDLVTKGTKEPYRVFTSRAEYRLLLREDNAYLRLGTYAYKFGLIDKVRYTQIMADKTHIEHTINYLQNHHIT
PSSSNLTMLASLGLPPISDKALLIHIVGREELDCALLRTLLTHLGITDVESMSDLAIEQIFIESKYFDYIQKQKQQIGQM
RQMLQVEIPRDFIFDNIPGLSLEVIEKLKKFTPKSLFEANEISGITPASIDVLHLYIHLHHKKKSQILV
>Mature_629_residues
MVIGGGHAGVEASIVSAKMGAKTHLITLLIQNIALASCNPAVGGLGKGHLVKEIDALGGVMGVITDKCGIQFRILNASKG
PAVRGTRAQIDMDRYSIFAKEIALNTPNLTISQESVESLIYEQDSKGRYIVKGVTTNIGKTYFAKKVILTTGTFLRGLVH
IGETKLQNGRFGEMSPQNLSNSLQDMGLTLGRLKTGTCARIDGRSIDFSALEIHNGDEKPPHFSYKTINFSPTQLPCFVT
YTNENTHKIIRDNFHRAPLFTGQIEGVGPRYCPSIEDKVNRFADKSRHQLFLEPQTQEAVEYYINGLSTSLPIDVQEAVI
HSIKGLENAHITRYGYAIEYDYVEPTELYHTLETKKCANLFLAGQINGTTGYEEAAAQGIMAGINATLSLQNKSFTLARN
EAYIGVMIDDLVTKGTKEPYRVFTSRAEYRLLLREDNAYLRLGTYAYKFGLIDKVRYTQIMADKTHIEHTINYLQNHHIT
PSSSNLTMLASLGLPPISDKALLIHIVGREELDCALLRTLLTHLGITDVESMSDLAIEQIFIESKYFDYIQKQKQQIGQM
RQMLQVEIPRDFIFDNIPGLSLEVIEKLKKFTPKSLFEANEISGITPASIDVLHLYIHLHHKKKSQILV

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=643, Percent_Identity=40.746500777605, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI19882217, Length=668, Percent_Identity=39.2215568862275, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI183227703, Length=683, Percent_Identity=38.3601756954612, Blast_Score=412, Evalue=1e-115,
Organism=Escherichia coli, GI2367273, Length=620, Percent_Identity=48.5483870967742, Blast_Score=568, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17534255, Length=624, Percent_Identity=38.3012820512821, Blast_Score=386, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321202, Length=619, Percent_Identity=43.4571890145396, Blast_Score=475, Evalue=1e-135,
Organism=Drosophila melanogaster, GI24658174, Length=642, Percent_Identity=40.4984423676012, Blast_Score=426, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_HELHP (Q7VK79)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859544.1
- ProteinModelPortal:   Q7VK79
- SMR:   Q7VK79
- GeneID:   1493168
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0013
- NMPDR:   fig|235279.1.peg.13
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   HHEP235279:HH_0013-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 70071; Mature: 70071

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIGGGHAGVEASIVSAKMGAKTHLITLLIQNIALASCNPAVGGLGKGHLVKEIDALGGV
CEECCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCHH
MGVITDKCGIQFRILNASKGPAVRGTRAQIDMDRYSIFAKEIALNTPNLTISQESVESLI
HHHHCCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEECHHHHHHHH
YEQDSKGRYIVKGVTTNIGKTYFAKKVILTTGTFLRGLVHIGETKLQNGRFGEMSPQNLS
HCCCCCCCEEEEEEECCCCHHHHHHHHEEECCHHHHHHHHHCCHHCCCCCCCCCCHHHHH
NSLQDMGLTLGRLKTGTCARIDGRSIDFSALEIHNGDEKPPHFSYKTINFSPTQLPCFVT
HHHHHHCCCHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEE
YTNENTHKIIRDNFHRAPLFTGQIEGVGPRYCPSIEDKVNRFADKSRHQLFLEPQTQEAV
ECCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHH
EYYINGLSTSLPIDVQEAVIHSIKGLENAHITRYGYAIEYDYVEPTELYHTLETKKCANL
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCE
FLAGQINGTTGYEEAAAQGIMAGINATLSLQNKSFTLARNEAYIGVMIDDLVTKGTKEPY
EEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCEEEEEEEHHHHHCCCCCHH
RVFTSRAEYRLLLREDNAYLRLGTYAYKFGLIDKVRYTQIMADKTHIEHTINYLQNHHIT
HHHHCCCEEEEEEEECCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSSSNLTMLASLGLPPISDKALLIHIVGREELDCALLRTLLTHLGITDVESMSDLAIEQI
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FIESKYFDYIQKQKQQIGQMRQMLQVEIPRDFIFDNIPGLSLEVIEKLKKFTPKSLFEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCHHHHCHH
EISGITPASIDVLHLYIHLHHKKKSQILV
HCCCCCCCHHEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MVIGGGHAGVEASIVSAKMGAKTHLITLLIQNIALASCNPAVGGLGKGHLVKEIDALGGV
CEECCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCHH
MGVITDKCGIQFRILNASKGPAVRGTRAQIDMDRYSIFAKEIALNTPNLTISQESVESLI
HHHHCCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEECHHHHHHHH
YEQDSKGRYIVKGVTTNIGKTYFAKKVILTTGTFLRGLVHIGETKLQNGRFGEMSPQNLS
HCCCCCCCEEEEEEECCCCHHHHHHHHEEECCHHHHHHHHHCCHHCCCCCCCCCCHHHHH
NSLQDMGLTLGRLKTGTCARIDGRSIDFSALEIHNGDEKPPHFSYKTINFSPTQLPCFVT
HHHHHHCCCHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEE
YTNENTHKIIRDNFHRAPLFTGQIEGVGPRYCPSIEDKVNRFADKSRHQLFLEPQTQEAV
ECCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHH
EYYINGLSTSLPIDVQEAVIHSIKGLENAHITRYGYAIEYDYVEPTELYHTLETKKCANL
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCE
FLAGQINGTTGYEEAAAQGIMAGINATLSLQNKSFTLARNEAYIGVMIDDLVTKGTKEPY
EEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCEEEEEEEHHHHHCCCCCHH
RVFTSRAEYRLLLREDNAYLRLGTYAYKFGLIDKVRYTQIMADKTHIEHTINYLQNHHIT
HHHHCCCEEEEEEEECCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSSSNLTMLASLGLPPISDKALLIHIVGREELDCALLRTLLTHLGITDVESMSDLAIEQI
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FIESKYFDYIQKQKQQIGQMRQMLQVEIPRDFIFDNIPGLSLEVIEKLKKFTPKSLFEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCHHHHCHH
EISGITPASIDVLHLYIHLHHKKKSQILV
HCCCCCCCHHEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954