Click here to switch to the map view.

The map label for this gene is argC

Identifier: 161546630

GI number: 161546630

Start: 647729

End: 648763

Strand: Direct

Name: argC

Synonym: HH0669

Alternate gene names: 161546630

Gene position: 647729-648763 (Clockwise)

Preceding gene: 32266167

Following gene: 32266169

Centisome position: 36.0

GC content: 39.42

Gene sequence:

>1035_bases
ATGTTAGCGCAACATATCAATGTCGGAATCATCGGAGTGAGTGGCTATACGGGCTTAGAACTTGTTAAGCTTATTCTTGC
TCACCCGATTTTTAAATTAAGCTACATCGCTAATACACAAGGAGAGATACATCTTGATGAGATTCATAAAATGCTCTTCT
CTCTTAGTCATCTGCCGGTTTGCAAGGCTGATGCCAAAGAAGCTGTAGATAAATGTGAGCTTATTTTCATTGCCCTGCCG
CATAAAAGTGCTATGACTATGGTGCGTGAGATTCTAAGCATTAAGCCAATAAAGATTGTTGATTTATCAGCTGACTACCG
CCTCAATGCGAAAAATTATACAGCGCATTATTGCCCTCATATTGATACAGAAAATCTCGCTAGCGCTGTGTATGGATTGC
CAGAATATAATCGTGCATTGATACAAAAATCTCATCTTGTGGCAAATCCGGGTTGCTATCCTACTGCTAGTCTTTTGGCT
CTGCTCCCTTTTTTGGATTATATTGATAGCTCTTGTGGTGTGTTTATTGATGCCAAAAGTGGTGTGAGTGGAGCAGGAAA
AAGCCTTACTGAGAATACACACTTTCCCCACATTAATGAGAATCTCTTTAGCTATTCCCCTCTTACACATCGTCACCAAA
TAGAAATTGCCGAAAAATGCCAAACTATTGGCGCTAAGGAAATGGATATTGTCTTTGTGCCACACCTTATGCCTATTACA
CGTGGTATGCTTATAAGCATATTTGCGACACTTCATTCACCACTAAACTCACAAGAAGCATATGAGATACTCCTGAATGC
CTATAAAAATGAGGCTTTTGTCCGAATCCGTAAGAGCCCTGTCAGTATTGCCCACGTTGTTGGTAGCCATTTTTGTGATA
TTTTTGTTGCTACTACGAACAAAAATATTTATATCAACTCTTCAATAGATAATCTTCTACGCGGAGCAAGCTCACAAGCT
TTGCTTAATGCTAACCTTATGTGTGGCTTAGATGAGCATTTAGGTGTGCCAAATATACCTTATGGTATTTTTTAG

Upstream 100 bases:

>100_bases
TTCATACTCCACATAGTCTTAATGAATGCCTTGATATGCGCGATTTTGAAATCTTTTGTGCTATTTTGCACGATTTTATT
ATCTCTTATAAGGGCTTATA

Downstream 100 bases:

>100_bases
GTTTTATTAATGAATCTAGCTCAAAGAGGTATTTTGCAAAATCAAGATACCAAAGATATTGCAAAAATATGGGAAGAGGC
ACCTTATATTAAAAATGATG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLAQHINVGIIGVSGYTGLELVKLILAHPIFKLSYIANTQGEIHLDEIHKMLFSLSHLPVCKADAKEAVDKCELIFIALP
HKSAMTMVREILSIKPIKIVDLSADYRLNAKNYTAHYCPHIDTENLASAVYGLPEYNRALIQKSHLVANPGCYPTASLLA
LLPFLDYIDSSCGVFIDAKSGVSGAGKSLTENTHFPHINENLFSYSPLTHRHQIEIAEKCQTIGAKEMDIVFVPHLMPIT
RGMLISIFATLHSPLNSQEAYEILLNAYKNEAFVRIRKSPVSIAHVVGSHFCDIFVATTNKNIYINSSIDNLLRGASSQA
LLNANLMCGLDEHLGVPNIPYGIF

Sequences:

>Translated_344_residues
MLAQHINVGIIGVSGYTGLELVKLILAHPIFKLSYIANTQGEIHLDEIHKMLFSLSHLPVCKADAKEAVDKCELIFIALP
HKSAMTMVREILSIKPIKIVDLSADYRLNAKNYTAHYCPHIDTENLASAVYGLPEYNRALIQKSHLVANPGCYPTASLLA
LLPFLDYIDSSCGVFIDAKSGVSGAGKSLTENTHFPHINENLFSYSPLTHRHQIEIAEKCQTIGAKEMDIVFVPHLMPIT
RGMLISIFATLHSPLNSQEAYEILLNAYKNEAFVRIRKSPVSIAHVVGSHFCDIFVATTNKNIYINSSIDNLLRGASSQA
LLNANLMCGLDEHLGVPNIPYGIF
>Mature_344_residues
MLAQHINVGIIGVSGYTGLELVKLILAHPIFKLSYIANTQGEIHLDEIHKMLFSLSHLPVCKADAKEAVDKCELIFIALP
HKSAMTMVREILSIKPIKIVDLSADYRLNAKNYTAHYCPHIDTENLASAVYGLPEYNRALIQKSHLVANPGCYPTASLLA
LLPFLDYIDSSCGVFIDAKSGVSGAGKSLTENTHFPHINENLFSYSPLTHRHQIEIAEKCQTIGAKEMDIVFVPHLMPIT
RGMLISIFATLHSPLNSQEAYEILLNAYKNEAFVRIRKSPVSIAHVVGSHFCDIFVATTNKNIYINSSIDNLLRGASSQA
LLNANLMCGLDEHLGVPNIPYGIF

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=338, Percent_Identity=33.7278106508876, Blast_Score=154, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6320913, Length=340, Percent_Identity=31.1764705882353, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37934; Mature: 37934

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQHINVGIIGVSGYTGLELVKLILAHPIFKLSYIANTQGEIHLDEIHKMLFSLSHLPV
CCCCEEEEEEEEECCCCHHHHHHHHHHCHHHEEEEEECCCCCEEHHHHHHHHHHHHCCCC
CKADAKEAVDKCELIFIALPHKSAMTMVREILSIKPIKIVDLSADYRLNAKNYTAHYCPH
CCCCHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCEEEECCC
IDTENLASAVYGLPEYNRALIQKSHLVANPGCYPTASLLALLPFLDYIDSSCGVFIDAKS
CCHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCC
GVSGAGKSLTENTHFPHINENLFSYSPLTHRHQIEIAEKCQTIGAKEMDIVFVPHLMPIT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
RGMLISIFATLHSPLNSQEAYEILLNAYKNEAFVRIRKSPVSIAHVVGSHFCDIFVATTN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCEEEEEEECC
KNIYINSSIDNLLRGASSQALLNANLMCGLDEHLGVPNIPYGIF
CEEEEECCHHHHHCCCCCCCEECCCEEECCHHHCCCCCCCCCCC
>Mature Secondary Structure
MLAQHINVGIIGVSGYTGLELVKLILAHPIFKLSYIANTQGEIHLDEIHKMLFSLSHLPV
CCCCEEEEEEEEECCCCHHHHHHHHHHCHHHEEEEEECCCCCEEHHHHHHHHHHHHCCCC
CKADAKEAVDKCELIFIALPHKSAMTMVREILSIKPIKIVDLSADYRLNAKNYTAHYCPH
CCCCHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCEEEECCC
IDTENLASAVYGLPEYNRALIQKSHLVANPGCYPTASLLALLPFLDYIDSSCGVFIDAKS
CCHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCC
GVSGAGKSLTENTHFPHINENLFSYSPLTHRHQIEIAEKCQTIGAKEMDIVFVPHLMPIT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
RGMLISIFATLHSPLNSQEAYEILLNAYKNEAFVRIRKSPVSIAHVVGSHFCDIFVATTN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCEEEEEEECC
KNIYINSSIDNLLRGASSQALLNANLMCGLDEHLGVPNIPYGIF
CEEEEECCHHHHHCCCCCCCEECCCEEECCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]