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The map label for this gene is argD

Identifier: 30065355

GI number: 30065355

Start: 4313314

End: 4314534

Strand: Direct

Name: argD

Synonym: S4385

Alternate gene names: 30065355

Gene position: 4313314-4314534 (Clockwise)

Preceding gene: 30065354

Following gene: 30065358

Centisome position: 93.78

GC content: 54.38

Gene sequence:

>1221_bases
ATGGCAATTGAACAAACAGCAATTACACGCGCGACTTTCGATGAAGTGATCCTGCCGATTTATGCTCCGGCAGAGTTTAT
TCCGGTAAAAGGTCAGGGCAGCCGAATCTGGGATCAGCAAGGCAAGGAGTATGTCGATTTCGCGGGTGGCATTGCAGTTA
CGGCGTTGGGCCATTGCCATCCTGCGCTGGTGAACGCGTTAAAAACCCAGGGCGAAACTCTGTGGCATATCAGTAACGTT
TTCACCAATGAACCGGCGCTGCGTCTTGGGCGCAAACTGATTGAGGCGACGTTTGCCGAACGCGTGGTGTTTATGAACTC
CGGCACGGAAGCTAACGAAACCGCCTTTAAACTGGCACGCCATTACGCCTGTGTGCGTCATAGCCCGTTCAAAACCAAAA
TTATTGCCTTCCATAACGCTTTTCATGGTCGCTCGCTGTTTACCGTTTCGGTGGGTGGGCAGCCAAAATATTCCGACGGC
TTTGGGCCGAAACCGGCAGACATCATCCACGTTCCCTTTAACGATCTCCATGCAGTGAAAGCGGTGATGGATGATCACAC
CTGTGCGGTGGTGGTTGAGCCGATCCAGGGCGAGGGCGGTGTGACGGCAGCGACGCCAGAGTTTTTGCAGGGCTTGCGCG
AGCTGTGCGATCAACATCAGGCATTATTGGTGTTTGATGAAGTGCAGTGCGGGATGGGGCGGACTGGCGATTTGTTTGCT
TACAGGTACTACGGTGTGACGCCGGATATTCTGACTTCTGCGAAAGCGTTAGGCGGCGGCTTCCCGATTAGCGCCATGCT
GACCACGGCGGAAATTGCTTCTGCGTTTCATCCTGGTTCTCACGGTTCCACCTACGGCGGTAATCCTCTGGCCTGTGCAG
TAGCGGGCGCGGCGTTTGATATCATCAATACCCCTGAAGTGCTGGAAGGCATTCAGGCGAAACGCCAGCGTTTTGTTGAC
CATTTGCAGAAGATCGATCAGCAGTACGATGTGTTTAGCGATATTCGCGGTATGGGGCTGTTAATTGGCGCGGAGCTGAA
ACCACACTACAAAGGTCGGGCGCGTGATTTCCTGTATGCGGGTGCAGAGGTTGGCGTAATGGTGCTGAATGCCGGACCGG
ATGTGATGCGTTTAGCACCGTCGCTGGTGGTGGAAGATGCGGATATCGATGAAGGGATGCAACGTTTCGCCCACGCGGTG
GCGAAGGTGGTTGGGGCGTAA

Upstream 100 bases:

>100_bases
TTCCTGCATCTCTGATTTCCGATTGCCATTCAGTGATTTTTTATGCATATTTTGTGATTATAATTTCACATTTATTTATG
CGTAACAGGGTGATCATGAG

Downstream 100 bases:

>100_bases
ATAAGACGTATCAGGCAAAATATGTCGGATGCGGCGTGAATGCCTTATCCGATGGTTTAGCCTGTATTACGCCTTCGAAT
CCCGCAACTTGCGACTCAGC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YRYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYAGAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAV
AKVVGA

Sequences:

>Translated_406_residues
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YRYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYAGAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAV
AKVVGA
>Mature_405_residues
AIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVF
TNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFAY
RYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDH
LQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYAGAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAVA
KVVGA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=37.037037037037, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=38.7755102040816, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28.9411764705882, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=31.1720698254364, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=31.5508021390374, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226442705, Length=401, Percent_Identity=29.925187032419, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24119277, Length=349, Percent_Identity=28.080229226361, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=98.7684729064039, Blast_Score=826, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=59.1939546599496, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1789016, Length=413, Percent_Identity=35.5932203389831, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=32.6732673267327, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=34.0966921119593, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=32.1766561514196, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=29.4685990338164, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=35.7333333333333, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=28.4064665127021, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=36.5384615384615, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=420, Percent_Identity=28.5714285714286, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=25.2873563218391, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=32.3170731707317, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=38.0352644836272, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=32.258064516129, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=29.2993630573248, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=439, Percent_Identity=25.2847380410023, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=34.7480106100796, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=27.9342723004695, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=27.790973871734, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=30.6413301662708, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281366494, Length=430, Percent_Identity=22.093023255814, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667139, Length=430, Percent_Identity=22.093023255814, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667143, Length=430, Percent_Identity=22.093023255814, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43822; Mature: 43690

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCH
CCCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YRYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFD
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHEEE
GAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAVAKVVGA
CCCCCEEEEECCCHHHHHCHHHEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCH
CCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YRYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFD
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHEEE
GAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAVAKVVGA
CCCCCEEEEECCCHHHHHCHHHEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]