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The map label for this gene is rtn

Identifier: 30063619

GI number: 30063619

Start: 2273382

End: 2274938

Strand: Direct

Name: rtn

Synonym: S2392

Alternate gene names: 30063619

Gene position: 2273382-2274938 (Clockwise)

Preceding gene: 30063618

Following gene: 30063620

Centisome position: 49.43

GC content: 50.1

Gene sequence:

>1557_bases
ATGTTCATACGCGCTCCCAATTCTGGACGTAAGCTCCTGCTTACCTGCATTGTAGCAGGCGTGATGATTGCGATACTGGT
TAGCTGCCTTCAGTTTTTAGTGGCCTGGCATAAGCACGAAGTCAAATACGACACACTGATTATCGACGTACAAAAGTATC
TCGATACCTATTTTGCCGACCTGAAATCCACTACTGACCGGCTTCAGCCGCTGACCTTAGATACCTGCCAGCAGGCTAAC
CCCGAACTGACCGCTCGCGCGGCGTTTAGCATGAATGTCCGTACGTTTGTGCTGGTGAAAGATAAAAAAACATTCTGTTC
ATCTGCGACTGGTGAGATGGACATTCCACTCAATGAATTGATTCCGGCGCTCGACATTAATAAAAACGTCGATATGGCGA
TCTTACCCGGCACGCCGATGGTGCCGAACAAACCCGCAATCGTCATCTGGTATCGCAACCCTTTGCTGAAAAATAGCGGT
GTGTTTGCCGCTCTGAATCTCAACCTGACGCCTTCTCTCTTTTATAGTTCACGGCAGGAAGATTACGATGGCGTCGCCCT
CATTATTGGCAATACTGCGCTATCTACCTTTTCTTCACGTTTGATGAACGTTAATGAATTAACCGACATGCCGGTCCGTG
AAACTAAAATTGCGGGCATTCCTCTGACCGTTCGGCTTTATGCGGATGACTGGACATGGAACGATGTGTGGTACGCATTT
TTACTGGGCGGCATGAGTGGAACTGTCGTTGGCCTGCTTTGCTATTACCTGATGAGCGTACGTATGCGCCCCGACAGAGA
AATCATGACCGCCATCAAGCGCGAACAATTTTACGTGGCGTATCAACCGGTGGTGGATACACAAGCTTTGCGGGTAACGG
GCCTGGAAGTACTGCTACGCTGGCGGCATCCTGTAGCGGGAGAAATTCCCCCGGATGCCTTCATTAACTTTGCCGAATCG
CAAAAGATGATTGTGCCGCTGACTCAGCACCTGTTTGAGTTAATTGCCCGCGATGCCGCAGAATTAGAAAAAGTACTGCC
GGTAGGCGTCAAATTTGGCATTAACATTGCGCCGGACCATCTGCACAGCGAAAGCTTTAAAGCAGATATCCAGAAACTGC
TCACTTCCCTGCCCGCACACCATTTCCAGATTGTGCTGGAAATTACCGAGCGCGATATGCTGAAAGAGCAAGAAGCCACA
CAACTCTTCGCCTGGCTGCACTCGGTCGGCGTAGAAATTGCTATTGATGACTTCGGCACCGGGCACAGCGCGCTTATCTA
TCTTGAGCGTTTTACGCTCGATTATCTGAAAATTGACCGTGGATTTATCAACGCCATCGGTACGGAAACGATCACTTCAC
CCGTACTTGACGCGGTGCTGACGCTGGCGAAACGTCTCAATATGCTGACAGTTACTGAAGGGGTCGAAACGCCGGAACAA
GCGCGATGGCTAAGCGAACGCGGCGTTAATTTCATGCAAGGCTACTGGATTAGTCACCCGTTACCGCTGGACGATTTTGT
TCGCTGGCTGAAGAAACCGTATACGCCGCAGTGGTAA

Upstream 100 bases:

>100_bases
TTCATCAGAGAAAATGATGTTTCCGCGTCTTGATCCAGGCTATAGTCCGGTCATTGTTATCTTTTAAATGTTGTCGTAAT
TTCAGGAAATTAACGGAATC

Downstream 100 bases:

>100_bases
GGTGTGCTTACGTCCCTTATTATTCATAGTGAAAGCATGCCGGATTGCGGCTAATGATGAGTAAAAGGAAATCCGTTGCA
GATGATTGTGCGCATACTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLIIDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTVVGLLCYYLMSVRMRPDREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAES
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVTEGVETPEQ
ARWLSERGVNFMQGYWISHPLPLDDFVRWLKKPYTPQW

Sequences:

>Translated_518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLIIDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTVVGLLCYYLMSVRMRPDREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAES
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVTEGVETPEQ
ARWLSERGVNFMQGYWISHPLPLDDFVRWLKKPYTPQW
>Mature_518_residues
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLIIDVQKYLDTYFADLKSTTDRLQPLTLDTCQQAN
PELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
LLGGMSGTVVGLLCYYLMSVRMRPDREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAES
QKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEAT
QLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVTEGVETPEQ
ARWLSERGVNFMQGYWISHPLPLDDFVRWLKKPYTPQW

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=99.034749034749, Blast_Score=1059, Evalue=0.0,
Organism=Escherichia coli, GI87081980, Length=518, Percent_Identity=28.7644787644788, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=38.8888888888889, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=36.4372469635627, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=30.2788844621514, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081743, Length=270, Percent_Identity=31.1111111111111, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787541, Length=249, Percent_Identity=30.1204819277108, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081921, Length=241, Percent_Identity=29.8755186721992, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=30.4347826086957, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=28.2786885245902, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=29.2181069958848, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787055, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787410, Length=226, Percent_Identity=24.7787610619469, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58610; Mature: 58610

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLIIDVQKYLDTYFAD
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHEEEEHHHHHHHHHHH
LKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNEL
HHHHHHHCCCCCHHHHHCCCCCEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHC
IPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQE
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCC
DYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
CCCCEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHH
LLGGMSGTVVGLLCYYLMSVRMRPDREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLR
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHH
WRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDH
HCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCHH
LHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGT
HCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVTEGVETPEQ
CCEEEEEEEHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHH
ARWLSERGVNFMQGYWISHPLPLDDFVRWLKKPYTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLIIDVQKYLDTYFAD
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHEEEEHHHHHHHHHHH
LKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNEL
HHHHHHHCCCCCHHHHHCCCCCEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHC
IPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQE
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCC
DYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAF
CCCCEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHH
LLGGMSGTVVGLLCYYLMSVRMRPDREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLR
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHH
WRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDH
HCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCHH
LHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGT
HCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVTEGVETPEQ
CCEEEEEEEHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHH
ARWLSERGVNFMQGYWISHPLPLDDFVRWLKKPYTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]