Click here to switch to the map view.

The map label for this gene is btuR

Identifier: 30062792

GI number: 30062792

Start: 1321918

End: 1322508

Strand: Reverse

Name: btuR

Synonym: S1357

Alternate gene names: 30062792

Gene position: 1322508-1321918 (Counterclockwise)

Preceding gene: 30062793

Following gene: 30062788

Centisome position: 28.75

GC content: 51.1

Gene sequence:

>591_bases
ATGAGTGATGAACGCTACCAACAGCGTCAGCAGCGAGTGAAAGAAAAAGTAGATGCTCGTGTGGCCCAGGCCCAGGATGA
ACGCGGTATTATCATCGTCTTTACCGGCAATGGAAAAGGCAAAACCACCGCGGCATTTGGTACGGCAACACGCGCAGTTG
GTCACGGAAAAAAAGTGGGCGTCGTGCAGTTTATTAAAGGCACCTGGCCTAATGGCGAACGCAATCTGCTGGAGCCACAT
GGCGTTGAGTTTCAGGTGATGGCAACGGGCTTTACCTGGGATACACAAAACCGCGAGTCTGATACCGCCGCCTGCCGCGA
AGTCTGGCAACATGCAAAGCGGATGCTTGCTGATTCCTCACTGGATATGGTTTTGCTTGATGAACTGACGTATATGGTGG
CGTATGACTATTTGCCACTGGAAGAAGTGGTGCAGGCGTTAAATGAACGTCCACATCAACAGACGGTGATTATCACGGGT
CGAGGCTGTCATCGGGATATTCTTGAACTGGCGGATACGGTAAGTGAGCTGCGCCCCATCAGACATGCGTTTGATGCCGG
TGTTAAGGCGCAAATAGGGATTGATTATTAA

Upstream 100 bases:

>100_bases
ATATCATGCCGCTCTACCTCTGGCTGATGGGCGATGACAGCCGCCGTAAAACCGGCATGACCTTTGACGCCCAACCGGGC
CGTAAACCAGGAATTTCCCA

Downstream 100 bases:

>100_bases
TCTGTAAAAATGCCGGATATGACGTCCGGCATACTTTGATTAACCGTTATTACGCCCGCCAGAACGACGACTGCCGCTCA
CCTGACTGTGACGTTTCACC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
RGCHRDILELADTVSELRPIRHAFDAGVKAQIGIDY

Sequences:

>Translated_196_residues
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
RGCHRDILELADTVSELRPIRHAFDAGVKAQIGIDY
>Mature_195_residues
SDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHG
VEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGR
GCHRDILELADTVSELRPIRHAFDAGVKAQIGIDY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=98.9795918367347, Blast_Score=406, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22041; Mature: 21910

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCC
VVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSS
HHHHEECCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
LDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGRGCHRDILELADTVSELRPI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RHAFDAGVKAQIGIDY
HHHHCCCCEEEEECCC
>Mature Secondary Structure 
SDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCC
VVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSS
HHHHEECCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
LDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGRGCHRDILELADTVSELRPI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
RHAFDAGVKAQIGIDY
HHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]