| Definition | Shigella flexneri 2a str. 2457T, complete genome. |
|---|---|
| Accession | NC_004741 |
| Length | 4,599,354 |
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The map label for this gene is yciK
Identifier: 30062793
GI number: 30062793
Start: 1322505
End: 1323263
Strand: Reverse
Name: yciK
Synonym: S1358
Alternate gene names: 30062793
Gene position: 1323263-1322505 (Counterclockwise)
Preceding gene: 30062795
Following gene: 30062792
Centisome position: 28.77
GC content: 52.44
Gene sequence:
>759_bases ATGCATTACCAGCCAAAACAAGATTTACTCAATGATCGCATTATCCTGGTGACGGGAGCCAGCGATGGGATTGGTCGTGA AGCCGCGATGACGTATGCACGCTATGGTGCGACAGTGATTCTGTTGGGCCGTAATGAAGAAAAATTACGTCAGGTAGCCA GCCACATAAACGAAGAAACTGGGCGTCAGCCACAGTGGTTTATTCTCGATTTGCTGACCTGCACGTCCGAAAATTGCCAA CAACTGGCACAGCGCATTGTCGTTAATTATCCGCGTCTGGATGGTGTTTTGCATAATGCCGGATTGCTCGGCGATGTTTG CCCAATGAGCGAACAAAATCCGCAGGTCTGGCAGGACGTCATGCAGATCAACGTTAATGCCACCTTTATGCTCACCCAGG CACTGCTTCCTTTATTACTCAAATCGGACGCCGGTTCACTGGTCTTTACTTCATCAAGCGTTGGACGTCAGGGACGAGCC AACTGGGGTGCATATGCAGCGTCGAAATTTGCCACCGAAGGGATGATGCAGGTACTGGCCGATGAATATCAGCAGCGCCT GCGCGTCAACTGCATTAACCCAGGCGGTACGCGCACCGCAATGCGCGCAAGCGCCTTCCCGACCGAAGATCCACAGAAAC TTAAAACACCCGCTGATATCATGCCGCTCTACCTCTGGCTGATGGGCGATGACAGCCGCCGTAAAACCGGCATGACCTTT GACGCCCAACCGGGCCGTAAACCAGGAATTTCCCAATGA
Upstream 100 bases:
>100_bases CGCCCCAGGCTGATTGAAATGCCCTTCTGTTTCAGGCATAAAGCCCCAAAGTCATAAAGTACACTGGCAGCGCGACAGAC AACGTCGTTGAGGAGTAGCC
Downstream 100 bases:
>100_bases GTGATGAACGCTACCAACAGCGTCAGCAGCGAGTGAAAGAAAAAGTAGATGCTCGTGTGGCCCAGGCCCAGGATGAACGC GGTATTATCATCGTCTTTAC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQPQWFILDLLTCTSENCQ QLAQRIVVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQINVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF DAQPGRKPGISQ
Sequences:
>Translated_252_residues MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQPQWFILDLLTCTSENCQ QLAQRIVVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQINVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF DAQPGRKPGISQ >Mature_252_residues MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQPQWFILDLLTCTSENCQ QLAQRIVVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQINVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF DAQPGRKPGISQ
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=31.0679611650485, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI142976729, Length=222, Percent_Identity=26.5765765765766, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=26.5873015873016, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI4504505, Length=236, Percent_Identity=26.6949152542373, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI10190704, Length=189, Percent_Identity=24.8677248677249, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=29.2682926829268, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI5031737, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI40807363, Length=207, Percent_Identity=25.1207729468599, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7657478, Length=222, Percent_Identity=29.2792792792793, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=28.1368821292776, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=25.4980079681275, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=26.6331658291457, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI59889578, Length=171, Percent_Identity=30.4093567251462, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI4557649, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=29.0476190476191, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=99.2063492063492, Blast_Score=523, Evalue=1e-150, Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=32.3770491803279, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=30.5220883534137, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=27.4193548387097, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1789208, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1786701, Length=206, Percent_Identity=28.6407766990291, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=22.7678571428571, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=28.0612244897959, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=25, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1787905, Length=232, Percent_Identity=27.5862068965517, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=30, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17551412, Length=219, Percent_Identity=28.7671232876712, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=34, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560150, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71997402, Length=253, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562906, Length=234, Percent_Identity=28.6324786324786, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=199, Percent_Identity=30.1507537688442, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=206, Percent_Identity=31.0679611650485, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508895, Length=212, Percent_Identity=26.8867924528302, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=30, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17570069, Length=203, Percent_Identity=27.5862068965517, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=27.710843373494, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=30.9644670050761, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=24.5210727969349, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI72000259, Length=202, Percent_Identity=27.7227722772277, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17562990, Length=191, Percent_Identity=28.2722513089005, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562904, Length=217, Percent_Identity=28.110599078341, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561402, Length=239, Percent_Identity=24.2677824267782, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17563726, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17560176, Length=180, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17562910, Length=193, Percent_Identity=26.4248704663212, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17564282, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538480, Length=211, Percent_Identity=25.1184834123223, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193204405, Length=212, Percent_Identity=27.3584905660377, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203117, Length=212, Percent_Identity=25, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17559104, Length=217, Percent_Identity=26.2672811059908, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=236, Percent_Identity=25.4237288135593, Blast_Score=80, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6322227, Length=215, Percent_Identity=28.8372093023256, Blast_Score=79, Evalue=9e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=226, Percent_Identity=27.4336283185841, Blast_Score=76, Evalue=6e-15, Organism=Saccharomyces cerevisiae, GI6322226, Length=194, Percent_Identity=27.319587628866, Blast_Score=72, Evalue=9e-14, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=28.5140562248996, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=28.1746031746032, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=32.0855614973262, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24640492, Length=182, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=26.7206477732794, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=34.1463414634146, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21358495, Length=209, Percent_Identity=29.1866028708134, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=26.5873015873016, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI281364892, Length=204, Percent_Identity=28.921568627451, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=28.042328042328, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=28.042328042328, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=28.3524904214559, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI45553409, Length=214, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24647948, Length=214, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24647946, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27975; Mature: 27975
Theoretical pI: Translated: 7.94; Mature: 7.94
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 6.0 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.4 %Met (Mature Protein) 6.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEET CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH GRQPQWFILDLLTCTSENCQQLAQRIVVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDV CCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH MQINVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMMQVLA HHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF HHHHHHHEEEEECCCCCCHHHCCCCCCCCCHHHHCCCHHHHHEEHEEECCCCCCCCCCEE DAQPGRKPGISQ CCCCCCCCCCCC >Mature Secondary Structure MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEET CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH GRQPQWFILDLLTCTSENCQQLAQRIVVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDV CCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH MQINVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMMQVLA HHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF HHHHHHHEEEEECCCCCCHHHCCCCCCCCCHHHHCCCHHHHHEEHEEECCCCCCCCCCEE DAQPGRKPGISQ CCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9097039; 9278503; 1885549 [H]