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The map label for this gene is trpS [H]

Identifier: 29349272

GI number: 29349272

Start: 5034089

End: 5035189

Strand: Reverse

Name: trpS [H]

Synonym: BT_3864

Alternate gene names: 29349272

Gene position: 5035189-5034089 (Counterclockwise)

Preceding gene: 29349275

Following gene: 29349248

Centisome position: 80.43

GC content: 48.23

Gene sequence:

>1101_bases
ATGGGAAAAGAAAAAATCATACTCACCGGTGACCGCCCTACCGGGAGACTTCATATCGGACACTATGTAGGTTCATTGAA
GCGCAGAGTTGACCTGCAAGATGCAGGTGATTATAGTAAGATGTTTATCTTTATTGCCGATTCACAAGCGTTGACGGACA
ATATAGATAATCCGGAGAAGGTACGTCAAAATGTAATTGAGGTTGCTCTTGACTATCTGGCATGTGGAATAGACCCGTCC
AAGGCTACCATCTTCATCCAGTCACAGATTCCGGAACTTTGCGAACTTAGTTTCTACTATATGGACCTCGTAAGCGTATC
CCGCTTACAACGTAACCCGACTGTGAAATCAGAAATACAGATGCGTAACTTTGAGGCAAGCATCCCTGTAGGGTTCTTCA
CTTATCCTATCAGTCAGGCTGCGGACATTACTGCCTTCCGGGCAACCACCGTCCCCGTCGGTGAAGACCAGGAACCGATG
CTCGAACAGGCTCGTGAAATCGTCCGCCGTTTCAACTATATCTATGGCGAAACGCTGGTAGAACCGGAAATCCTGTTGCC
GGACAACGCTGCCTGCCTGCGTCTGCCGGGAACGGACGGCAAAGCCAAGATGAGTAAATCACTCGGCAACTGTATCTACC
TGTCGGAAGAACCGGAAGAAATTCAGAAGAAAATCATGAGTATGTATACCGATCCGGGACACCTCCGCGTACAGGATCCG
GGCAAGATTGAAGGTAATACCGTATTTACATACCTGGATGCTTTCTGCCGTCCGGAACACTTCGAACGCTATCTGCCGGA
TTATCCGAATCTGGATGAACTGAAAGCGCATTATCAACGCGGTGGACTGGGTGATGTGAAGGTAAAACGCTTCCTGAACG
CTATCATGCAGGAAACACTGGAACCGATCCGCAATCGTCGTAAAGAGTTCAGCAAGGATATTCCTGCCGTTTACGAGATG
CTACAAAAAGGATGCGAAGTAGCCAGAGCTGCCGCTGCCGAAACATTGGCGGATGTGAAGAAGGCTATGAAGATCAACTA
TTTCGATGACAAAGAACTGATTGAAGAGCAGGTGAAACGCTTCGCGGCTTCACAGGAATAA

Upstream 100 bases:

>100_bases
GCAATAGTAAGCATTAGTAACGAAGTAGCTCCATTTTGACGCATCTTTCATTTTTTATCCTTATCTTTGTCGCTAAATCT
ATTATAATAAGGTAACAACA

Downstream 100 bases:

>100_bases
AGATAATAAAGACGAATATAATAAAGTAAAGGCTGCCGTCCACTTTCGAACAGGCAGCCTTTACTTTATTATATAGTCTG
CTCAATCAGTTTCATCTTCA

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGKEKIILTGDRPTGRLHIGHYVGSLKRRVDLQDAGDYSKMFIFIADSQALTDNIDNPEKVRQNVIEVALDYLACGIDPS
KATIFIQSQIPELCELSFYYMDLVSVSRLQRNPTVKSEIQMRNFEASIPVGFFTYPISQAADITAFRATTVPVGEDQEPM
LEQAREIVRRFNYIYGETLVEPEILLPDNAACLRLPGTDGKAKMSKSLGNCIYLSEEPEEIQKKIMSMYTDPGHLRVQDP
GKIEGNTVFTYLDAFCRPEHFERYLPDYPNLDELKAHYQRGGLGDVKVKRFLNAIMQETLEPIRNRRKEFSKDIPAVYEM
LQKGCEVARAAAAETLADVKKAMKINYFDDKELIEEQVKRFAASQE

Sequences:

>Translated_366_residues
MGKEKIILTGDRPTGRLHIGHYVGSLKRRVDLQDAGDYSKMFIFIADSQALTDNIDNPEKVRQNVIEVALDYLACGIDPS
KATIFIQSQIPELCELSFYYMDLVSVSRLQRNPTVKSEIQMRNFEASIPVGFFTYPISQAADITAFRATTVPVGEDQEPM
LEQAREIVRRFNYIYGETLVEPEILLPDNAACLRLPGTDGKAKMSKSLGNCIYLSEEPEEIQKKIMSMYTDPGHLRVQDP
GKIEGNTVFTYLDAFCRPEHFERYLPDYPNLDELKAHYQRGGLGDVKVKRFLNAIMQETLEPIRNRRKEFSKDIPAVYEM
LQKGCEVARAAAAETLADVKKAMKINYFDDKELIEEQVKRFAASQE
>Mature_365_residues
GKEKIILTGDRPTGRLHIGHYVGSLKRRVDLQDAGDYSKMFIFIADSQALTDNIDNPEKVRQNVIEVALDYLACGIDPSK
ATIFIQSQIPELCELSFYYMDLVSVSRLQRNPTVKSEIQMRNFEASIPVGFFTYPISQAADITAFRATTVPVGEDQEPML
EQAREIVRRFNYIYGETLVEPEILLPDNAACLRLPGTDGKAKMSKSLGNCIYLSEEPEEIQKKIMSMYTDPGHLRVQDPG
KIEGNTVFTYLDAFCRPEHFERYLPDYPNLDELKAHYQRGGLGDVKVKRFLNAIMQETLEPIRNRRKEFSKDIPAVYEML
QKGCEVARAAAAETLADVKKAMKINYFDDKELIEEQVKRFAASQE

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=341, Percent_Identity=29.9120234604106, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=37.1584699453552, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789786, Length=346, Percent_Identity=31.7919075144509, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71982800, Length=347, Percent_Identity=28.5302593659942, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982793, Length=344, Percent_Identity=28.1976744186047, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320474, Length=359, Percent_Identity=30.9192200557103, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24666151, Length=343, Percent_Identity=32.0699708454811, Blast_Score=158, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 41659; Mature: 41528

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKEKIILTGDRPTGRLHIGHYVGSLKRRVDLQDAGDYSKMFIFIADSQALTDNIDNPEK
CCCCCEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHCCCCCHHH
VRQNVIEVALDYLACGIDPSKATIFIQSQIPELCELSFYYMDLVSVSRLQRNPTVKSEIQ
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MRNFEASIPVGFFTYPISQAADITAFRATTVPVGEDQEPMLEQAREIVRRFNYIYGETLV
HHCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
EPEILLPDNAACLRLPGTDGKAKMSKSLGNCIYLSEEPEEIQKKIMSMYTDPGHLRVQDP
CCCEECCCCCCEEEECCCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCEEECCC
GKIEGNTVFTYLDAFCRPEHFERYLPDYPNLDELKAHYQRGGLGDVKVKRFLNAIMQETL
CCCCCCCHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EPIRNRRKEFSKDIPAVYEMLQKGCEVARAAAAETLADVKKAMKINYFDDKELIEEQVKR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FAASQE
HHCCCC
>Mature Secondary Structure 
GKEKIILTGDRPTGRLHIGHYVGSLKRRVDLQDAGDYSKMFIFIADSQALTDNIDNPEK
CCCCEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHCCCCCHHH
VRQNVIEVALDYLACGIDPSKATIFIQSQIPELCELSFYYMDLVSVSRLQRNPTVKSEIQ
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MRNFEASIPVGFFTYPISQAADITAFRATTVPVGEDQEPMLEQAREIVRRFNYIYGETLV
HHCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
EPEILLPDNAACLRLPGTDGKAKMSKSLGNCIYLSEEPEEIQKKIMSMYTDPGHLRVQDP
CCCEECCCCCCEEEECCCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCEEECCC
GKIEGNTVFTYLDAFCRPEHFERYLPDYPNLDELKAHYQRGGLGDVKVKRFLNAIMQETL
CCCCCCCHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EPIRNRRKEFSKDIPAVYEMLQKGCEVARAAAAETLADVKKAMKINYFDDKELIEEQVKR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FAASQE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA