Click here to switch to the map view.

The map label for this gene is efp [H]

Identifier: 29349117

GI number: 29349117

Start: 4820156

End: 4820722

Strand: Reverse

Name: efp [H]

Synonym: BT_3709

Alternate gene names: 29349117

Gene position: 4820722-4820156 (Counterclockwise)

Preceding gene: 29349125

Following gene: 29349116

Centisome position: 77.0

GC content: 43.39

Gene sequence:

>567_bases
ATGATTAATGCTCAAGACATCAAAAACGGAACTTGTATCCGTATGGACGGAAAGCTCTATTTCTGTATAGAATTCCTGCA
TGTAAAACCAGGTAAAGGTAACACATTTATGCGTACCAAGCTGAAAGACGTAGTAAGCGGTTATGTTCTCGAACGCCGTT
TCAATATCGGTGAAAAACTGGAAGATGTACGCGTTGAACGTCGTCCATACCAATTCCTGTATAAAGAAGGAGAAGACTAT
ATCTTCATGAACCAGGAAACTTTTGACCAACACCCCATCGCTCACGACCTGATCAATGGTGTAGACTTCTTGCTCGAAGG
TGCAGTGCTGGACGTTGTTTCTGACGCTTCTACCGAAACTGTACTTTATGCAGACATGCCGATCAAAGTTCAGATGAAGG
TTACTTATACAGAACCGGGAATGAAAGGTGATACAGCCACCAACACACTGAAACCTGCTACCGTAGAATCAGGTGCAACA
GTACGTGTGCCTTTGTTCATCAGCGAAGGTGAAACAATTGAAATCGACACTCGTGACGGTTCTTACGTAGGACGCGTAAA
AGCATAA

Upstream 100 bases:

>100_bases
CTCAAAAGTTTTTGTGTTTTTTACTGATTTAGATTACTTTTGCACTCGAATTACGACGAAGACAATTAAATAACAATAAT
ATAATAAGAAAAACAGCAGT

Downstream 100 bases:

>100_bases
ATGTCATACAAATGACATAAAGAAACGGTGGATTTGCTTCGGCACTTCCACCGTTTTTTATTACCTTTGTCCATCACTAA
CCCTAATATTAAGATACAAA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MINAQDIKNGTCIRMDGKLYFCIEFLHVKPGKGNTFMRTKLKDVVSGYVLERRFNIGEKLEDVRVERRPYQFLYKEGEDY
IFMNQETFDQHPIAHDLINGVDFLLEGAVLDVVSDASTETVLYADMPIKVQMKVTYTEPGMKGDTATNTLKPATVESGAT
VRVPLFISEGETIEIDTRDGSYVGRVKA

Sequences:

>Translated_188_residues
MINAQDIKNGTCIRMDGKLYFCIEFLHVKPGKGNTFMRTKLKDVVSGYVLERRFNIGEKLEDVRVERRPYQFLYKEGEDY
IFMNQETFDQHPIAHDLINGVDFLLEGAVLDVVSDASTETVLYADMPIKVQMKVTYTEPGMKGDTATNTLKPATVESGAT
VRVPLFISEGETIEIDTRDGSYVGRVKA
>Mature_188_residues
MINAQDIKNGTCIRMDGKLYFCIEFLHVKPGKGNTFMRTKLKDVVSGYVLERRFNIGEKLEDVRVERRPYQFLYKEGEDY
IFMNQETFDQHPIAHDLINGVDFLLEGAVLDVVSDASTETVLYADMPIKVQMKVTYTEPGMKGDTATNTLKPATVESGAT
VRVPLFISEGETIEIDTRDGSYVGRVKA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=191, Percent_Identity=37.696335078534, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 21228; Mature: 21228

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAQDIKNGTCIRMDGKLYFCIEFLHVKPGKGNTFMRTKLKDVVSGYVLERRFNIGEKL
CCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHEEECCCCCHHH
EDVRVERRPYQFLYKEGEDYIFMNQETFDQHPIAHDLINGVDFLLEGAVLDVVSDASTET
HHHHHCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCHHEEEECCCCCCE
VLYADMPIKVQMKVTYTEPGMKGDTATNTLKPATVESGATVRVPLFISEGETIEIDTRDG
EEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCC
SYVGRVKA
CEEEEECC
>Mature Secondary Structure
MINAQDIKNGTCIRMDGKLYFCIEFLHVKPGKGNTFMRTKLKDVVSGYVLERRFNIGEKL
CCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHEEECCCCCHHH
EDVRVERRPYQFLYKEGEDYIFMNQETFDQHPIAHDLINGVDFLLEGAVLDVVSDASTET
HHHHHCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCHHEEEECCCCCCE
VLYADMPIKVQMKVTYTEPGMKGDTATNTLKPATVESGATVRVPLFISEGETIEIDTRDG
EEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCCC
SYVGRVKA
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA