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The map label for this gene is nahA [H]

Identifier: 29349006

GI number: 29349006

Start: 4659096

End: 4660709

Strand: Reverse

Name: nahA [H]

Synonym: BT_3598

Alternate gene names: 29349006

Gene position: 4660709-4659096 (Counterclockwise)

Preceding gene: 29349007

Following gene: 29349005

Centisome position: 74.45

GC content: 42.07

Gene sequence:

>1614_bases
ATGAAACTATTACTTACAACCTTGGCAATAGTCTATCTAAGTTTGTTCATGAGCCTGCAAGCACAAGAACAGGTACGGGT
TATCCCCTATCCTGCTGAAGTCACCATGCAAGCAGAAACGTGTAAACTCAAATCGGGTCAGAAAATCCACTATCTGGATG
CCAGTTTATATAAAGAAGCAGCATTCCTTGAAAAGAAACTCGCTGATTTAAACTATAAAATGAAAGTAATCCCCGGCAAA
AAAGCTGTGAAAGGAATCAACTTATCATTAAACAATAGACTGCAAAACAAAGAGGGCTATCAGCTGATTATCGCCCCCAA
ACAGGTCCTAATCAAAGGAGGAAGTCCAGCTGGAGTTTTCTATGGTATTCAAACGCTATTACAGCAGTTAACCAACGGAG
ATCTAAGATGTGGAACGATAGAAGACGCCCCGCGTTATGAATGGAGAGGATATATGCTTGATGAAGCACGTCACTTTTCC
GGCGAAAAAAGGGTAAAACAAATCCTTGACCTGATGGCATATTATAAGATGAATCGCTTCCATTGGCATCTGACAGACGC
ACAAGGATGGAGAATCGAAATTAAACAATACCCTAAACTGGCAACTATAGGAGGAGAAGGTTGCCATAGTGATCCGGATA
CACCGGCACAATATTATACACAAGAGCAGATCCGTGATATCATAGCATATGCCAAAGAACGTCATATTGAAATTATACCC
GAAATAGACATGCCCGGACATGCCACAGCAGCCAATAAAGCTTACCCGGAATACTCAGGCGGAGGAACGGAAGAACATCC
GGAATTCACTTTTAACGTCGGCAAAGAAGAAACTTATACTTATCTGACTAATATACTAAAAGAAATAGCTGCCTTATTCC
CTTCTCCATATTTACATATCGGAGGCGACGAAGTAGCTTACGGAATCAAGGCATGGGAAACAGACCCACATGTACAAGCA
CTATTGAAACGCGAAGGGTTACAAACTGTAAAGGAAGCAGAACGCTACTTTATGCATAGAATGACAGATGTAGTAAACTC
ACTAGGTAAAACTTTAGTCGGTTGGGATGAACTTCTCGACTTGAATGTAAAGCAAGATAATACTATCATTATGTGGTGGA
GACATGATAAACCCGATTACCTGCGCAAATCACTGACCAAAGGATATTCGACTATCATGTGTCCGCGCAAACCGCTTTAT
TTTGACTTCGTACAATATAAAGACCACAAATGGGGACGAATCTGGGACGGATTCTGCCCAATAGAAGATGTATATGCTTT
CCCCGACAAATGGTTTGCCGAATGGGGAGTGTCAGCCTCTGACCTCTCACATGTCAAAGGCATACAGGCCAATACATGGA
CGGAACTAATGCATACTAAAGATCGGGTAGATTTCATGATCTTTCCCCGCCTCTGCGCACTGGCAGAATCAGCTTGGTCC
GCACCGACAGTCAAAGACTACGACAAGTTCCTGTCACGTATGGAAGATGCATTCACCTTATTTGATAAGCTGAATATTTA
TTACTTTGATTATCGTAATCCTCAGCACCATCCGGAACCGGCTGGTCCTGTCATCAAAAAGAAAGAAAAAATACAAATGG
ATTTCCGTGACTAA

Upstream 100 bases:

>100_bases
CCCTAATGAGACCCGTACCATCACTGCGACAGTATCCATAGAGGATTTACATGGAGAAAATCCTATAATTATTATTAAAT
AACTAATAAAACCAAGAAAC

Downstream 100 bases:

>100_bases
AAAAAGAAATGCTACATGAAGATTCTTATCTACTTTTTAATAATTGTACTGTGGAGCATCAATATGGAGGCAAAAGTCAA
ATTGCCTCCACTACTTAGTG

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MKLLLTTLAIVYLSLFMSLQAQEQVRVIPYPAEVTMQAETCKLKSGQKIHYLDASLYKEAAFLEKKLADLNYKMKVIPGK
KAVKGINLSLNNRLQNKEGYQLIIAPKQVLIKGGSPAGVFYGIQTLLQQLTNGDLRCGTIEDAPRYEWRGYMLDEARHFS
GEKRVKQILDLMAYYKMNRFHWHLTDAQGWRIEIKQYPKLATIGGEGCHSDPDTPAQYYTQEQIRDIIAYAKERHIEIIP
EIDMPGHATAANKAYPEYSGGGTEEHPEFTFNVGKEETYTYLTNILKEIAALFPSPYLHIGGDEVAYGIKAWETDPHVQA
LLKREGLQTVKEAERYFMHRMTDVVNSLGKTLVGWDELLDLNVKQDNTIIMWWRHDKPDYLRKSLTKGYSTIMCPRKPLY
FDFVQYKDHKWGRIWDGFCPIEDVYAFPDKWFAEWGVSASDLSHVKGIQANTWTELMHTKDRVDFMIFPRLCALAESAWS
APTVKDYDKFLSRMEDAFTLFDKLNIYYFDYRNPQHHPEPAGPVIKKKEKIQMDFRD

Sequences:

>Translated_537_residues
MKLLLTTLAIVYLSLFMSLQAQEQVRVIPYPAEVTMQAETCKLKSGQKIHYLDASLYKEAAFLEKKLADLNYKMKVIPGK
KAVKGINLSLNNRLQNKEGYQLIIAPKQVLIKGGSPAGVFYGIQTLLQQLTNGDLRCGTIEDAPRYEWRGYMLDEARHFS
GEKRVKQILDLMAYYKMNRFHWHLTDAQGWRIEIKQYPKLATIGGEGCHSDPDTPAQYYTQEQIRDIIAYAKERHIEIIP
EIDMPGHATAANKAYPEYSGGGTEEHPEFTFNVGKEETYTYLTNILKEIAALFPSPYLHIGGDEVAYGIKAWETDPHVQA
LLKREGLQTVKEAERYFMHRMTDVVNSLGKTLVGWDELLDLNVKQDNTIIMWWRHDKPDYLRKSLTKGYSTIMCPRKPLY
FDFVQYKDHKWGRIWDGFCPIEDVYAFPDKWFAEWGVSASDLSHVKGIQANTWTELMHTKDRVDFMIFPRLCALAESAWS
APTVKDYDKFLSRMEDAFTLFDKLNIYYFDYRNPQHHPEPAGPVIKKKEKIQMDFRD
>Mature_537_residues
MKLLLTTLAIVYLSLFMSLQAQEQVRVIPYPAEVTMQAETCKLKSGQKIHYLDASLYKEAAFLEKKLADLNYKMKVIPGK
KAVKGINLSLNNRLQNKEGYQLIIAPKQVLIKGGSPAGVFYGIQTLLQQLTNGDLRCGTIEDAPRYEWRGYMLDEARHFS
GEKRVKQILDLMAYYKMNRFHWHLTDAQGWRIEIKQYPKLATIGGEGCHSDPDTPAQYYTQEQIRDIIAYAKERHIEIIP
EIDMPGHATAANKAYPEYSGGGTEEHPEFTFNVGKEETYTYLTNILKEIAALFPSPYLHIGGDEVAYGIKAWETDPHVQA
LLKREGLQTVKEAERYFMHRMTDVVNSLGKTLVGWDELLDLNVKQDNTIIMWWRHDKPDYLRKSLTKGYSTIMCPRKPLY
FDFVQYKDHKWGRIWDGFCPIEDVYAFPDKWFAEWGVSASDLSHVKGIQANTWTELMHTKDRVDFMIFPRLCALAESAWS
APTVKDYDKFLSRMEDAFTLFDKLNIYYFDYRNPQHHPEPAGPVIKKKEKIQMDFRD

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=412, Percent_Identity=30.3398058252427, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI4504373, Length=415, Percent_Identity=27.4698795180723, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17569815, Length=444, Percent_Identity=25.4504504504505, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281365639, Length=428, Percent_Identity=28.2710280373832, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24657474, Length=428, Percent_Identity=28.2710280373832, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24657468, Length=428, Percent_Identity=28.2710280373832, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17647501, Length=428, Percent_Identity=28.2710280373832, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24653074, Length=492, Percent_Identity=27.2357723577236, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45551090, Length=492, Percent_Identity=27.2357723577236, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17933586, Length=435, Percent_Identity=23.9080459770115, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 62208; Mature: 62208

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLTTLAIVYLSLFMSLQAQEQVRVIPYPAEVTMQAETCKLKSGQKIHYLDASLYKEA
CHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEHHHEECCCCCEEEEECHHHHHHH
AFLEKKLADLNYKMKVIPGKKAVKGINLSLNNRLQNKEGYQLIIAPKQVLIKGGSPAGVF
HHHHHHHHCCCCEEEEECCHHHHEECCEEECCCCCCCCCCEEEEECCEEEEECCCCCHHH
YGIQTLLQQLTNGDLRCGTIEDAPRYEWRGYMLDEARHFSGEKRVKQILDLMAYYKMNRF
HHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCCCE
HWHLTDAQGWRIEIKQYPKLATIGGEGCHSDPDTPAQYYTQEQIRDIIAYAKERHIEIIP
EEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
EIDMPGHATAANKAYPEYSGGGTEEHPEFTFNVGKEETYTYLTNILKEIAALFPSPYLHI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEE
GGDEVAYGIKAWETDPHVQALLKREGLQTVKEAERYFMHRMTDVVNSLGKTLVGWDELLD
CCCHHEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
LNVKQDNTIIMWWRHDKPDYLRKSLTKGYSTIMCPRKPLYFDFVQYKDHKWGRIWDGFCP
CEECCCCEEEEEEECCCHHHHHHHHHCCCCEEECCCCCCEEEHHHHCCCCCCCCCCCCCC
IEDVYAFPDKWFAEWGVSASDLSHVKGIQANTWTELMHTKDRVDFMIFPRLCALAESAWS
HHHHHCCCCHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHCC
APTVKDYDKFLSRMEDAFTLFDKLNIYYFDYRNPQHHPEPAGPVIKKKEKIQMDFRD
CCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MKLLLTTLAIVYLSLFMSLQAQEQVRVIPYPAEVTMQAETCKLKSGQKIHYLDASLYKEA
CHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEHHHEECCCCCEEEEECHHHHHHH
AFLEKKLADLNYKMKVIPGKKAVKGINLSLNNRLQNKEGYQLIIAPKQVLIKGGSPAGVF
HHHHHHHHCCCCEEEEECCHHHHEECCEEECCCCCCCCCCEEEEECCEEEEECCCCCHHH
YGIQTLLQQLTNGDLRCGTIEDAPRYEWRGYMLDEARHFSGEKRVKQILDLMAYYKMNRF
HHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCCCE
HWHLTDAQGWRIEIKQYPKLATIGGEGCHSDPDTPAQYYTQEQIRDIIAYAKERHIEIIP
EEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
EIDMPGHATAANKAYPEYSGGGTEEHPEFTFNVGKEETYTYLTNILKEIAALFPSPYLHI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEE
GGDEVAYGIKAWETDPHVQALLKREGLQTVKEAERYFMHRMTDVVNSLGKTLVGWDELLD
CCCHHEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
LNVKQDNTIIMWWRHDKPDYLRKSLTKGYSTIMCPRKPLYFDFVQYKDHKWGRIWDGFCP
CEECCCCEEEEEEECCCHHHHHHHHHCCCCEEECCCCCCEEEHHHHCCCCCCCCCCCCCC
IEDVYAFPDKWFAEWGVSASDLSHVKGIQANTWTELMHTKDRVDFMIFPRLCALAESAWS
HHHHHCCCCHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHCC
APTVKDYDKFLSRMEDAFTLFDKLNIYYFDYRNPQHHPEPAGPVIKKKEKIQMDFRD
CCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]