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The map label for this gene is nagB [H]

Identifier: 29348995

GI number: 29348995

Start: 4641673

End: 4642458

Strand: Reverse

Name: nagB [H]

Synonym: BT_3587

Alternate gene names: 29348995

Gene position: 4642458-4641673 (Counterclockwise)

Preceding gene: 29348996

Following gene: 29348994

Centisome position: 74.16

GC content: 38.93

Gene sequence:

>786_bases
ATGTTATCTACAATCAATGAAACATACCTGTTTCAACAAGATCTATTAACAGTCAAAATGTTCCCTTCTATCCAACAGAT
GGGGAAATGTGCTGCGACAGAAGTTACTAACAAAATATGCGAACTTCTCAAAGAGAAAGCTGAAATCAATATGATTTTTG
CCGCAGCTCCTTCACAAAATGAATTCTTAAGTCATCTTATTCACAGTAAACAGATTGACTGGAGCAGAATCAACGCTTTC
CACATGGATGAATACATCGGCATTCATCCGGAAGCCCCACAAAGTTTCGGAAATTTTCTCCGTCAGCGCATCTTCGACAA
AGTCCCGTTCAAGACTGTAAACTATCTGAACGGACAAGCAGAAAACCTTGAAGAAGAATGCAAACGTTATTCCGAATTGC
TGCTTCGTCATCCTGTCGATATTGTCTGTCTGGGAATTGGAGAAAACGGTCATATTGCATTCAATGATCCGGATGTAGCC
AATTTCAACGACTCCCATTTAGTTAAAGTAGTAGAACTCGACCCGATATGTCGCCAGCAACAAGTGAATGAAAAATGCTT
TGAAGCATTCGACCTTGTTCCTGCTAAAGCACTGACTCTTACCATTCCAGCCTTATTAAAAGCGGACTGGATGTTCTGCA
TTGTGCCTTTTAAAAATAAAGCCAATGCAGTATACAACACTCTTTATGGAGAAATTTCCGAAAAATGTCCGGCCAGTATA
TTACGCAAAAAAGAAAATTCTTGTTTATATTTGGATCCTGAAAGTGCAGAACGAATAAACTTATAA

Upstream 100 bases:

>100_bases
CATGTGGATTCCCAAAAGGGTTCTTTGGAGGAAGGTAAAGATGCCGACATCGTCACCTTCGACAATCAAATTAACGTAAC
AACAACTATATCAAAAGGCC

Downstream 100 bases:

>100_bases
ATACATATGAAAAATATCTTATTTATCCTCCTTACTTTCTTGTCTGTCAGCTTCAGACTATATGCGCAGGATGTAATTAA
AATAGGAATTATCGGGCTCG

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLSTINETYLFQQDLLTVKMFPSIQQMGKCAATEVTNKICELLKEKAEINMIFAAAPSQNEFLSHLIHSKQIDWSRINAF
HMDEYIGIHPEAPQSFGNFLRQRIFDKVPFKTVNYLNGQAENLEEECKRYSELLLRHPVDIVCLGIGENGHIAFNDPDVA
NFNDSHLVKVVELDPICRQQQVNEKCFEAFDLVPAKALTLTIPALLKADWMFCIVPFKNKANAVYNTLYGEISEKCPASI
LRKKENSCLYLDPESAERINL

Sequences:

>Translated_261_residues
MLSTINETYLFQQDLLTVKMFPSIQQMGKCAATEVTNKICELLKEKAEINMIFAAAPSQNEFLSHLIHSKQIDWSRINAF
HMDEYIGIHPEAPQSFGNFLRQRIFDKVPFKTVNYLNGQAENLEEECKRYSELLLRHPVDIVCLGIGENGHIAFNDPDVA
NFNDSHLVKVVELDPICRQQQVNEKCFEAFDLVPAKALTLTIPALLKADWMFCIVPFKNKANAVYNTLYGEISEKCPASI
LRKKENSCLYLDPESAERINL
>Mature_261_residues
MLSTINETYLFQQDLLTVKMFPSIQQMGKCAATEVTNKICELLKEKAEINMIFAAAPSQNEFLSHLIHSKQIDWSRINAF
HMDEYIGIHPEAPQSFGNFLRQRIFDKVPFKTVNYLNGQAENLEEECKRYSELLLRHPVDIVCLGIGENGHIAFNDPDVA
NFNDSHLVKVVELDPICRQQQVNEKCFEAFDLVPAKALTLTIPALLKADWMFCIVPFKNKANAVYNTLYGEISEKCPASI
LRKKENSCLYLDPESAERINL

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=189, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19923881, Length=191, Percent_Identity=25.130890052356, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786893, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789530, Length=206, Percent_Identity=25.7281553398058, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17554876, Length=189, Percent_Identity=24.8677248677249, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581960, Length=191, Percent_Identity=23.5602094240838, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920764, Length=191, Percent_Identity=23.5602094240838, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 29789; Mature: 29789

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTINETYLFQQDLLTVKMFPSIQQMGKCAATEVTNKICELLKEKAEINMIFAAAPSQN
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHH
EFLSHLIHSKQIDWSRINAFHMDEYIGIHPEAPQSFGNFLRQRIFDKVPFKTVNYLNGQA
HHHHHHHHHCCCCHHHHCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCC
ENLEEECKRYSELLLRHPVDIVCLGIGENGHIAFNDPDVANFNDSHLVKVVELDPICRQQ
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHH
QVNEKCFEAFDLVPAKALTLTIPALLKADWMFCIVPFKNKANAVYNTLYGEISEKCPASI
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHHH
LRKKENSCLYLDPESAERINL
HHCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MLSTINETYLFQQDLLTVKMFPSIQQMGKCAATEVTNKICELLKEKAEINMIFAAAPSQN
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHH
EFLSHLIHSKQIDWSRINAFHMDEYIGIHPEAPQSFGNFLRQRIFDKVPFKTVNYLNGQA
HHHHHHHHHCCCCHHHHCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCC
ENLEEECKRYSELLLRHPVDIVCLGIGENGHIAFNDPDVANFNDSHLVKVVELDPICRQQ
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHH
QVNEKCFEAFDLVPAKALTLTIPALLKADWMFCIVPFKNKANAVYNTLYGEISEKCPASI
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHHH
LRKKENSCLYLDPESAERINL
HHCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA