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The map label for this gene is ftsW [H]

Identifier: 29348858

GI number: 29348858

Start: 4442944

End: 4444260

Strand: Reverse

Name: ftsW [H]

Synonym: BT_3449

Alternate gene names: 29348858

Gene position: 4444260-4442944 (Counterclockwise)

Preceding gene: 29348859

Following gene: 29348857

Centisome position: 70.99

GC content: 50.27

Gene sequence:

>1317_bases
ATGGATTTATTAAAGAGCATATTTAAAGGCGACAAGGTAATCTGGATTATCTTCCTCTGTCTCTGCCTCATCTCGATTAT
CGAGGTGTTTTCGGCAGCATCGACGCTGACGTACAAAAGCGGCGACCACTGGGGACCGATAACACAGCACTCCATCATCC
TGATGGTGGGTGCCGTAGTAGTGGTATTTCTGCATAACGTCCCCTACAAATGGTTCCAGGTATTCCCCGTCTTCCTGTAT
CCGATTTCCCTCGTTCTGCTGGCATTCGTCACGCTGATGGGTATCATTACAGGCGACCGTGTCAATGGGGCAGCCCGCTG
GATGACCTTTATGGGACTGCAATTCCAGCCTTCGGAACTGGCAAAGATGGCTGTCATCATTGCCGTTTCGTTCATCCTGT
CCAAGAGGCAGGATGAAGAAGGAGCCAACCCCAAAGCCTTTAAATACATCATGATCCTTACCGGACTGGTCCTTTTGCTG
ATTGCTCCGGAAAACCTGTCAACAGCCATGTTGCTGTTCGGTGTCGTATTCATGATGATGTTCATCGGACGGGTAGCGGC
AAAGAAACTCCTTCTGTTGGCAGGAGGACTTGTGCTGATTGTCGCACTCGGCGTAGGTACGGTAGTTGCCATCCCTGCCA
AAACGCTGCACAATACCCCCGGACTTCATCGCCTGGAGACTTGGCAGAACCGTATCAAAGGCTTTTTTGATAAAGACGAA
GTGCCCGCAGCCAAATTCGATATAGACAAAGACGCACAGATCGCCCATGCCCGTATTGCCATCGCTACCAGTCACGTAGT
GGGCAAAGGACCGGGAAACTCCATCCAGCGTGATTTCCTCAGTCAGGCATTCTCCGACTTTATCTTTGCGATTGTCATCG
AAGAAATGGGATTGATAGGAGGTATATTTGTCGTATTCCTCTACCTCTGTCTGCTGATGCGGGCGGGACGCATCGCGCAA
AAGTGCGAACGGACCTTCCCCGCCTTCCTTGTCATGGGTATCGCTTTGCTTCTGGTATCGCAGGCGATACTGAATATGAT
GGTTGCCGTGGGACTGTTCCCCGTAACAGGCCAACCCCTGCCTTTGGTCAGCAAGGGAGGTACAAGTACACTGATCAACT
GTGCTTATATCGGAATGATATTAAGCGTGAGCCGATATACCGCTCATCTGGAAGAACAGAAAGCGCATGATGCACAGATT
CAGATGCAGATAGAAACCGGAACAGCTACTTCAGAAGCACAAGCCGCCGCCGAACCTACTGCACAGATTCTGAACAGCGA
TGCCAAGTTTGAGGATGAACATGATAGCAGTAAATGA

Upstream 100 bases:

>100_bases
GAAACCGTATTGTTAAGCCCCTGCTGCGCCTCATTCGACCTCTTCAAGAGTTACGAAGACCGCGGCGATCAGTTTAAGAA
ATATGTAAGAGAATTATAAA

Downstream 100 bases:

>100_bases
AGATGAACGGATAGAAAAAAGGATTATTATGGAGAAAGAACTTAGAATTATCATCAGCGGTGGAGGCACAGGAGGACATA
TCTTCCCTGCCGTATCTATC

Product: rod shape-determining protein rodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MDLLKSIFKGDKVIWIIFLCLCLISIIEVFSAASTLTYKSGDHWGPITQHSIILMVGAVVVVFLHNVPYKWFQVFPVFLY
PISLVLLAFVTLMGIITGDRVNGAARWMTFMGLQFQPSELAKMAVIIAVSFILSKRQDEEGANPKAFKYIMILTGLVLLL
IAPENLSTAMLLFGVVFMMMFIGRVAAKKLLLLAGGLVLIVALGVGTVVAIPAKTLHNTPGLHRLETWQNRIKGFFDKDE
VPAAKFDIDKDAQIAHARIAIATSHVVGKGPGNSIQRDFLSQAFSDFIFAIVIEEMGLIGGIFVVFLYLCLLMRAGRIAQ
KCERTFPAFLVMGIALLLVSQAILNMMVAVGLFPVTGQPLPLVSKGGTSTLINCAYIGMILSVSRYTAHLEEQKAHDAQI
QMQIETGTATSEAQAAAEPTAQILNSDAKFEDEHDSSK

Sequences:

>Translated_438_residues
MDLLKSIFKGDKVIWIIFLCLCLISIIEVFSAASTLTYKSGDHWGPITQHSIILMVGAVVVVFLHNVPYKWFQVFPVFLY
PISLVLLAFVTLMGIITGDRVNGAARWMTFMGLQFQPSELAKMAVIIAVSFILSKRQDEEGANPKAFKYIMILTGLVLLL
IAPENLSTAMLLFGVVFMMMFIGRVAAKKLLLLAGGLVLIVALGVGTVVAIPAKTLHNTPGLHRLETWQNRIKGFFDKDE
VPAAKFDIDKDAQIAHARIAIATSHVVGKGPGNSIQRDFLSQAFSDFIFAIVIEEMGLIGGIFVVFLYLCLLMRAGRIAQ
KCERTFPAFLVMGIALLLVSQAILNMMVAVGLFPVTGQPLPLVSKGGTSTLINCAYIGMILSVSRYTAHLEEQKAHDAQI
QMQIETGTATSEAQAAAEPTAQILNSDAKFEDEHDSSK
>Mature_438_residues
MDLLKSIFKGDKVIWIIFLCLCLISIIEVFSAASTLTYKSGDHWGPITQHSIILMVGAVVVVFLHNVPYKWFQVFPVFLY
PISLVLLAFVTLMGIITGDRVNGAARWMTFMGLQFQPSELAKMAVIIAVSFILSKRQDEEGANPKAFKYIMILTGLVLLL
IAPENLSTAMLLFGVVFMMMFIGRVAAKKLLLLAGGLVLIVALGVGTVVAIPAKTLHNTPGLHRLETWQNRIKGFFDKDE
VPAAKFDIDKDAQIAHARIAIATSHVVGKGPGNSIQRDFLSQAFSDFIFAIVIEEMGLIGGIFVVFLYLCLLMRAGRIAQ
KCERTFPAFLVMGIALLLVSQAILNMMVAVGLFPVTGQPLPLVSKGGTSTLINCAYIGMILSVSRYTAHLEEQKAHDAQI
QMQIETGTATSEAQAAAEPTAQILNSDAKFEDEHDSSK

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=389, Percent_Identity=28.0205655526992, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786853, Length=340, Percent_Identity=27.9411764705882, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47837; Mature: 47837

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]