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The map label for this gene is murG

Identifier: 29348857

GI number: 29348857

Start: 4441797

End: 4442915

Strand: Reverse

Name: murG

Synonym: BT_3448

Alternate gene names: 29348857

Gene position: 4442915-4441797 (Counterclockwise)

Preceding gene: 29348858

Following gene: 29348856

Centisome position: 70.97

GC content: 49.33

Gene sequence:

>1119_bases
ATGGAGAAAGAACTTAGAATTATCATCAGCGGTGGAGGCACAGGAGGACATATCTTCCCTGCCGTATCTATCGCCAACGC
TATAATAGAGCTGCGACCGGACGCGAAAATCTTATTTGTGGGAGCCGAGGGCCGTATGGAGATGCAGCGGGTTCCCGATG
CAGGCTATAAGATTATCGGGTTACCGATAGCCGGTTTTGACCGCAAACATTTATGGAAAAACGTATCCGTACTGATCAAA
CTGGCACGAAGCCAGTGGAAAGCGCGCAGCATCATCAAAAACTTCCGCCCACAAGTAGCGGTAGGCGTAGGAGGATACGC
CAGCGGACCGACACTCAAAACTGCCGGAATGATGGGAGTGCCGACTCTGATTCAGGAACAGAACTCGTATGCCGGAGTCA
CCAACAAGTTGCTGGCACAAAAAGCAAAGGCTATTTGTGTCGCTTATGATGGAATGGAAAAGTTCTTTCCTGCCGATAAG
ATTATAATGACCGGAAATCCCGTTCGCCAGAATCTGACGAAGGATATGCCGGAAAAAGGCGCGGCACTGCGTTCCTTTAA
TCTGCAGCCGGATAAGAAGACAATTCTGATTGTAGGCGGTAGCCTTGGCGCACGTACCATTAACAATACGCTGACCGCAG
CCTTAGCTACAATAAAAGAAAACAACGATATACAGTTCATCTGGCAGACCGGAAAATATTACTATCCGCAGGTGACAGAA
GCCGTACGGGCAGCAGGAGAACTTCCAAATCTGTACGTGACGGACTTCATCAAGGATATGGCAGCCGCTTACGCGGCTTC
CGACCTAGTGATTTCACGTGCGGGAGCCGGTTCTATTTCAGAGTTTTGTCTGTTGCACAAGCCTGTGGTTCTGGTTCCTT
CGCCCAATGTGGCAGAAGATCATCAGACCAAGAATGCACTGGCACTGGTAGACAAACAAGCCGCCATCTACGTAAAAGAC
AGCGAAGCAGAAGCAAAGTTGATGGATGTAGCCCTGAACACAGTAGCTGACGACCGGAAACTGAAAGAACTAAGTGAGAA
TATAGCCAAGTTGGCTTTGCCCGACTCTGCACGAATCATCGCGCAGGAAGTAATCAAGCTGGCAGAAGCAGAAAACTAG

Upstream 100 bases:

>100_bases
GCCGCCGAACCTACTGCACAGATTCTGAACAGCGATGCCAAGTTTGAGGATGAACATGATAGCAGTAAATGAAGATGAAC
GGATAGAAAAAAGGATTATT

Downstream 100 bases:

>100_bases
TTGAGGGAATGCAAAAATCGCAACTATCCCAATTAGGATTGACTAAAAAGTCAGTAGAATCTCCATTCTCCTCCTTCCAG
AAGGAGGAGAATGAAAATAC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MEKELRIIISGGGTGGHIFPAVSIANAIIELRPDAKILFVGAEGRMEMQRVPDAGYKIIGLPIAGFDRKHLWKNVSVLIK
LARSQWKARSIIKNFRPQVAVGVGGYASGPTLKTAGMMGVPTLIQEQNSYAGVTNKLLAQKAKAICVAYDGMEKFFPADK
IIMTGNPVRQNLTKDMPEKGAALRSFNLQPDKKTILIVGGSLGARTINNTLTAALATIKENNDIQFIWQTGKYYYPQVTE
AVRAAGELPNLYVTDFIKDMAAAYAASDLVISRAGAGSISEFCLLHKPVVLVPSPNVAEDHQTKNALALVDKQAAIYVKD
SEAEAKLMDVALNTVADDRKLKELSENIAKLALPDSARIIAQEVIKLAEAEN

Sequences:

>Translated_372_residues
MEKELRIIISGGGTGGHIFPAVSIANAIIELRPDAKILFVGAEGRMEMQRVPDAGYKIIGLPIAGFDRKHLWKNVSVLIK
LARSQWKARSIIKNFRPQVAVGVGGYASGPTLKTAGMMGVPTLIQEQNSYAGVTNKLLAQKAKAICVAYDGMEKFFPADK
IIMTGNPVRQNLTKDMPEKGAALRSFNLQPDKKTILIVGGSLGARTINNTLTAALATIKENNDIQFIWQTGKYYYPQVTE
AVRAAGELPNLYVTDFIKDMAAAYAASDLVISRAGAGSISEFCLLHKPVVLVPSPNVAEDHQTKNALALVDKQAAIYVKD
SEAEAKLMDVALNTVADDRKLKELSENIAKLALPDSARIIAQEVIKLAEAEN
>Mature_372_residues
MEKELRIIISGGGTGGHIFPAVSIANAIIELRPDAKILFVGAEGRMEMQRVPDAGYKIIGLPIAGFDRKHLWKNVSVLIK
LARSQWKARSIIKNFRPQVAVGVGGYASGPTLKTAGMMGVPTLIQEQNSYAGVTNKLLAQKAKAICVAYDGMEKFFPADK
IIMTGNPVRQNLTKDMPEKGAALRSFNLQPDKKTILIVGGSLGARTINNTLTAALATIKENNDIQFIWQTGKYYYPQVTE
AVRAAGELPNLYVTDFIKDMAAAYAASDLVISRAGAGSISEFCLLHKPVVLVPSPNVAEDHQTKNALALVDKQAAIYVKD
SEAEAKLMDVALNTVADDRKLKELSENIAKLALPDSARIIAQEVIKLAEAEN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=369, Percent_Identity=33.6043360433604, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BACTN (Q8A258)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_812360.1
- ProteinModelPortal:   Q8A258
- SMR:   Q8A258
- GeneID:   1075127
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_3448
- NMPDR:   fig|226186.1.peg.3447
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q8A258
- ProtClustDB:   PRK00726
- BioCyc:   BTHE226186:BT_3448-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40243; Mature: 40243

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKELRIIISGGGTGGHIFPAVSIANAIIELRPDAKILFVGAEGRMEMQRVPDAGYKIIG
CCCEEEEEEECCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCCCCHHHHCCCCCCEEEE
LPIAGFDRKHLWKNVSVLIKLARSQWKARSIIKNFRPQVAVGVGGYASGPTLKTAGMMGV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCC
PTLIQEQNSYAGVTNKLLAQKAKAICVAYDGMEKFFPADKIIMTGNPVRQNLTKDMPEKG
CHHHHCCCCCCHHHHHHHHHHHHEEEEEECCHHHHCCCCEEEECCCHHHHHHHHCCCCCC
AALRSFNLQPDKKTILIVGGSLGARTINNTLTAALATIKENNDIQFIWQTGKYYYPQVTE
CCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCHHHH
AVRAAGELPNLYVTDFIKDMAAAYAASDLVISRAGAGSISEFCLLHKPVVLVPSPNVAED
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCEEEECCCCCCCC
HQTKNALALVDKQAAIYVKDSEAEAKLMDVALNTVADDRKLKELSENIAKLALPDSARII
CCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHH
AQEVIKLAEAEN
HHHHHHHHCCCC
>Mature Secondary Structure
MEKELRIIISGGGTGGHIFPAVSIANAIIELRPDAKILFVGAEGRMEMQRVPDAGYKIIG
CCCEEEEEEECCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCCCCHHHHCCCCCCEEEE
LPIAGFDRKHLWKNVSVLIKLARSQWKARSIIKNFRPQVAVGVGGYASGPTLKTAGMMGV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCC
PTLIQEQNSYAGVTNKLLAQKAKAICVAYDGMEKFFPADKIIMTGNPVRQNLTKDMPEKG
CHHHHCCCCCCHHHHHHHHHHHHEEEEEECCHHHHCCCCEEEECCCHHHHHHHHCCCCCC
AALRSFNLQPDKKTILIVGGSLGARTINNTLTAALATIKENNDIQFIWQTGKYYYPQVTE
CCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCHHHH
AVRAAGELPNLYVTDFIKDMAAAYAASDLVISRAGAGSISEFCLLHKPVVLVPSPNVAED
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCEEEECCCCCCCC
HQTKNALALVDKQAAIYVKDSEAEAKLMDVALNTVADDRKLKELSENIAKLALPDSARII
CCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHH
AQEVIKLAEAEN
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663928