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The map label for this gene is aspC [H]

Identifier: 29348784

GI number: 29348784

Start: 4351512

End: 4352672

Strand: Reverse

Name: aspC [H]

Synonym: BT_3375

Alternate gene names: 29348784

Gene position: 4352672-4351512 (Counterclockwise)

Preceding gene: 29348785

Following gene: 29348783

Centisome position: 69.53

GC content: 36.61

Gene sequence:

>1161_bases
ATGATACAATTATCAGAAATAACAAACTCTATATCCCCTTCCTTAACAAGGCGTCTATTTAATTTGGCCCAAAAATATGA
CAATGTTATAGACTTCACATTGGGAGACCCGGATATACATCCACACGATAAAATAAAAGAAGCTGGCTGTAAAGCGATAC
TGGAAGGTCGTACAAGATACTCCCCTAATGCCGGATTATTAGAATTAAGAGAAATAATATCTTCCAGATACAAGTTACAA
TATAATATAGAATACAACCCGACAAATGAGATTATGGTTACAGTTGGGGGAATGGAAGGATTATATTTAACCCTGCTAGC
CATTCTAAACAGAGGGGATGAAGTCATTATACCAGCTCCATATTGGATAAACTATGTACAGATGGTATGTATGTGTAGTG
GAGAGCCCATTATCACAGCTCCTGTCAGCACCAATGACTTATCGATATCTATAGAAAATATAAGGAAGGCAATCACTCCT
AAAACAAAAGCTATTATTTTAAATACGCCCAGCAACCCTTCCGGGCGGATAATTTCTGATGACTCCATCCAACAAATAGC
ACAGATAGCTATTGAGAATGATTTGATAGTAATAACAGATGAGGTATACAAAACACTACTTTATGATAATGCTCATTTCA
AAAGTATTGTTACATGCGACAAGATGAAGGAACGCACTGTTGTTATCAATAGTTTATCAAAAGAATTCTGTATGACCGGA
TGGCGTTTGGGTTATATAGCTGCACCTTCAGAGTTAATATCAGTGATGACAATGTTTCAAGAGAACATAGCTGCTTGTGC
TCCATTGCCGTCTCAGTATGCAGCTATAGAAGCACTAAGAAATTCGGAGAAATATTCGGCTGGTATGATTGAGGAATTCA
CTCTCCGCCGAAATGTTTTATTGGAAGAAGTTGCCAAAATCAAAACAATAACAGTCGATGCGCCACAAGGAACCTTCTAT
GCAATGTTAAATATAAAATCTACCGGATTAAAATCTGAGGAGTTCGCATATGCCCTTTTAGAAAAAGAACAAGTGGCAGT
GGTTCCTGGAATAACTTACGGTGATTGTTGCGAGGATTTTATCCGGATTGCTTTTACATTAGATATATATAAAATTAAAG
AAGGAATTCAAAGACTTAAGCGATTTGTCGAAAGTTTATAA

Upstream 100 bases:

>100_bases
ATAGCAACCCAAATGTCCAATAACGTCATCTGCTTGCCAATGCACCATGCTTTAAGTGAAAATGAAGTCGAGTATATCCT
CCAAATTATAAAGAAATAGT

Downstream 100 bases:

>100_bases
GATGAAAAAAGTTTTAATGCTAGGAGGCTCTTTATATCAGGTCTATGCGATTAAAGAAGCTGTAAAAATGGGATATTATG
TAATCACCTGCGATTACTTG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MIQLSEITNSISPSLTRRLFNLAQKYDNVIDFTLGDPDIHPHDKIKEAGCKAILEGRTRYSPNAGLLELREIISSRYKLQ
YNIEYNPTNEIMVTVGGMEGLYLTLLAILNRGDEVIIPAPYWINYVQMVCMCSGEPIITAPVSTNDLSISIENIRKAITP
KTKAIILNTPSNPSGRIISDDSIQQIAQIAIENDLIVITDEVYKTLLYDNAHFKSIVTCDKMKERTVVINSLSKEFCMTG
WRLGYIAAPSELISVMTMFQENIAACAPLPSQYAAIEALRNSEKYSAGMIEEFTLRRNVLLEEVAKIKTITVDAPQGTFY
AMLNIKSTGLKSEEFAYALLEKEQVAVVPGITYGDCCEDFIRIAFTLDIYKIKEGIQRLKRFVESL

Sequences:

>Translated_386_residues
MIQLSEITNSISPSLTRRLFNLAQKYDNVIDFTLGDPDIHPHDKIKEAGCKAILEGRTRYSPNAGLLELREIISSRYKLQ
YNIEYNPTNEIMVTVGGMEGLYLTLLAILNRGDEVIIPAPYWINYVQMVCMCSGEPIITAPVSTNDLSISIENIRKAITP
KTKAIILNTPSNPSGRIISDDSIQQIAQIAIENDLIVITDEVYKTLLYDNAHFKSIVTCDKMKERTVVINSLSKEFCMTG
WRLGYIAAPSELISVMTMFQENIAACAPLPSQYAAIEALRNSEKYSAGMIEEFTLRRNVLLEEVAKIKTITVDAPQGTFY
AMLNIKSTGLKSEEFAYALLEKEQVAVVPGITYGDCCEDFIRIAFTLDIYKIKEGIQRLKRFVESL
>Mature_386_residues
MIQLSEITNSISPSLTRRLFNLAQKYDNVIDFTLGDPDIHPHDKIKEAGCKAILEGRTRYSPNAGLLELREIISSRYKLQ
YNIEYNPTNEIMVTVGGMEGLYLTLLAILNRGDEVIIPAPYWINYVQMVCMCSGEPIITAPVSTNDLSISIENIRKAITP
KTKAIILNTPSNPSGRIISDDSIQQIAQIAIENDLIVITDEVYKTLLYDNAHFKSIVTCDKMKERTVVINSLSKEFCMTG
WRLGYIAAPSELISVMTMFQENIAACAPLPSQYAAIEALRNSEKYSAGMIEEFTLRRNVLLEEVAKIKTITVDAPQGTFY
AMLNIKSTGLKSEEFAYALLEKEQVAVVPGITYGDCCEDFIRIAFTLDIYKIKEGIQRLKRFVESL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=373, Percent_Identity=30.8310991957105, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI56713256, Length=373, Percent_Identity=30.8310991957105, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=24.8743718592965, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=24.8743718592965, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=23.1788079470199, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=21.3903743315508, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI187936925, Length=206, Percent_Identity=26.2135922330097, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI14211921, Length=206, Percent_Identity=26.2135922330097, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=28.3333333333333, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=23.8961038961039, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788627, Length=397, Percent_Identity=24.6851385390428, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=321, Percent_Identity=28.6604361370716, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71994472, Length=321, Percent_Identity=28.6604361370716, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=286, Percent_Identity=30.4195804195804, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=24.8, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=25.1889168765743, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28573069, Length=341, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646114, Length=341, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573067, Length=341, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573065, Length=341, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=20.4787234042553, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43310; Mature: 43310

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLSEITNSISPSLTRRLFNLAQKYDNVIDFTLGDPDIHPHDKIKEAGCKAILEGRTRY
CEEHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
SPNAGLLELREIISSRYKLQYNIEYNPTNEIMVTVGGMEGLYLTLLAILNRGDEVIIPAP
CCCCCHHHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECCH
YWINYVQMVCMCSGEPIITAPVSTNDLSISIENIRKAITPKTKAIILNTPSNPSGRIISD
HHHHHHHHHHHCCCCCEEECCCCCCCEEEEHHHHHHHHCCCCCEEEEECCCCCCCCEECC
DSIQQIAQIAIENDLIVITDEVYKTLLYDNAHFKSIVTCDKMKERTVVINSLSKEFCMTG
HHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
WRLGYIAAPSELISVMTMFQENIAACAPLPSQYAAIEALRNSEKYSAGMIEEFTLRRNVL
CEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
LEEVAKIKTITVDAPQGTFYAMLNIKSTGLKSEEFAYALLEKEQVAVVPGITYGDCCEDF
HHHHHHEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHH
IRIAFTLDIYKIKEGIQRLKRFVESL
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQLSEITNSISPSLTRRLFNLAQKYDNVIDFTLGDPDIHPHDKIKEAGCKAILEGRTRY
CEEHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
SPNAGLLELREIISSRYKLQYNIEYNPTNEIMVTVGGMEGLYLTLLAILNRGDEVIIPAP
CCCCCHHHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECCH
YWINYVQMVCMCSGEPIITAPVSTNDLSISIENIRKAITPKTKAIILNTPSNPSGRIISD
HHHHHHHHHHHCCCCCEEECCCCCCCEEEEHHHHHHHHCCCCCEEEEECCCCCCCCEECC
DSIQQIAQIAIENDLIVITDEVYKTLLYDNAHFKSIVTCDKMKERTVVINSLSKEFCMTG
HHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
WRLGYIAAPSELISVMTMFQENIAACAPLPSQYAAIEALRNSEKYSAGMIEEFTLRRNVL
CEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
LEEVAKIKTITVDAPQGTFYAMLNIKSTGLKSEEFAYALLEKEQVAVVPGITYGDCCEDF
HHHHHHEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHH
IRIAFTLDIYKIKEGIQRLKRFVESL
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]