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The map label for this gene is yicI [C]

Identifier: 29348708

GI number: 29348708

Start: 4229123

End: 4231174

Strand: Reverse

Name: yicI [C]

Synonym: BT_3299

Alternate gene names: 29348708

Gene position: 4231174-4229123 (Counterclockwise)

Preceding gene: 29348709

Following gene: 29348707

Centisome position: 67.59

GC content: 43.47

Gene sequence:

>2052_bases
ATGGTTGGGGACGGAATCGCAAAATTCATCCCGGAAGGCTTCGACGCTCAAAAGATACCTTCTTTTGCAATAGAAAAAGA
ACCACGCGAACAAGGAGCACTTCCTGCCGACTGGGTACTTGTTCCCGAGTTCTCACTCACGGATGGTAAAGCAAACGCAT
CATTAACAGTGCCGGAAGGTACAAGCATCTATGGCGGTGGTGAAGTGACCGGTTCACTTCTGAGAAATGGAAAGACCATC
AAATTATGGAATACAGACTCAGGAGCTTATGGTGTAGACAAAGGTACTCGTCTGTATCAATCACATCCTTGGATGATGGG
AGTGCGAAAGGACGGAACAGCTTTTGGAATTTTATTCGATACTACTTGGAAAGCAGAACTAAGCAGTACAGACGAAAAAA
TCGAATTAAAAAGTGAAGGAATACCCTTTCGGGTATTCATCATTGACAGGGAATCTCCACAAGCAGTCATTCGCGGACTA
TCCGAACTGACCGGCACAATGCCAATGATTCCTCGCTGGGCACTAGGTTATCAGCAATGCCGGTTCTCATATTCTCCCGA
CAGCCGTGTCATTGAAATAGCAGATACTTTCAGACTAAAAAGAATACCATGTGATGTTATCTGGATGGACATTGATTATA
TGGACGGATACCGCATCTTTACCTTTAATCCGAAAAGTTTTCCGAATCCTAAAGCGGTGAACCGTGATTTGCACATACGT
GGATTCCATTCTGCATGGATGATTGACCCGGGAGCAAAAGTTGACCCTAACTATTTCGTATATAAATCGGGAACAGAAAA
TGACGTTTGGGTGAAAACAGCAGACGGTAAGAACTTCCACGGTGATGCATGGCCGGGAGCAGCAGCATTCCCTGATTTTA
CTTCTCCTAAAGTAAACAAATGGTGGAGAAACTTATATAAAGATTTTCTAGCACAAGGAGTAGATGGCGTATGGAATGAT
GTTAACGAACCCCAGATCAATGATACGCCCAACAAAACAATGCCGGAAGACAACCTGCATCGTGGAGGAGGAAAGCTTCC
GGCAGGTACACATCTTCAGTATCATAATGTATATGGCTTCCTGATGGTTAAAGCATCCAGGGAAGGTATACTGGATGCTC
GTCCAGAAAAACGTCCTTTCATTCTGACACGTTCCAACTTCCTTGGGGGACAACGTTATGCCGCTACATGGACTGGCGAC
AACGGTTCTTGCTGGGATCATCTAAAAATGTCAGTTCCCATGTCATTAACATTGGGATTATCCGGTCAACCGTTTAGTGG
TGCAGATATAGGCGGTTTCTTATTCAATGCTGATGCTGACTTATTCGGCAACTGGATTGGTTTCGGTGCCTTTTATCCTT
TCGCACGTGGTCATGCTTGCGCCGGAACAAACAACAAGGAACCATGGGTATTTGGACAAAAAGTAGAAGATGCCTCACGC
ATCGCTTTGGAACGTAGATATATACTACTACCCTACTTTTATACACTCTTACACGAAGCCTCAACTAATGGCATGCCTAT
TATGCGTCCTGTCTTCTTCTCCGACCCTAAAGACTTGTCACTGAGAGCAGAGGAAGAAGCTTTCCTTGTCGGTGATAATT
TACTTATCATTCCAGCATTTGCTAATCAACCGGCACTTCCGAAAGGGATCTGGAAAGAACTGTCACTTGTAGAAGGAGAT
CAGAATGATAAATATCAGGCAAAAATGAAGATTCGTGGGGGAGCTATCATTCCGACTGGAAAAATAATTCAGAACACTAC
AGAAAATTCATTAGATCCTCTGACATTACTAGTGTGTCTGGACGAACAGGGCAAAGCTTCCGGAAATATGTATTGGGATG
CGGGAGATGGTTGGTCTTACAAAAAAGGGGACTATAGCCTGCTACAATTTGTCGCAGAGCGAAATGGTGATAAAGTGACT
GTAAAGCTAACAAAGAAAACCGGAAAATACAACACTGAGAATAAAGACATGGCAGTGATTAAAATTATAACAGATCAAGG
CATACGTCAAGCCAGTGGAAATCTAGTGGAAGGTATTGAAATAAGACTATAA

Upstream 100 bases:

>100_bases
GAAATATATTTGTATCAAAACTGTAGCAATTTACTTGCTCGCAACCTTACCTTTATTGGCGAACGCCTCAACACACAAGG
TAAAAATTACACATAGCGTC

Downstream 100 bases:

>100_bases
AAAAGCACTATACTTTGTTTGGAAACCTAAAAAAAAAGTTTTATGAAAAAAGAGCACATGAAAAAGCAATATCCCCATTG
GTGCGGGGTATTGCTACTGT

Product: alpha-glucosidase II

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MVGDGIAKFIPEGFDAQKIPSFAIEKEPREQGALPADWVLVPEFSLTDGKANASLTVPEGTSIYGGGEVTGSLLRNGKTI
KLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGILFDTTWKAELSSTDEKIELKSEGIPFRVFIIDRESPQAVIRGL
SELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFRLKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIR
GFHSAWMIDPGAKVDPNYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQGVDGVWND
VNEPQINDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGFLMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGD
NGSCWDHLKMSVPMSLTLGLSGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASR
IALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIPAFANQPALPKGIWKELSLVEGD
QNDKYQAKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCLDEQGKASGNMYWDAGDGWSYKKGDYSLLQFVAERNGDKVT
VKLTKKTGKYNTENKDMAVIKIITDQGIRQASGNLVEGIEIRL

Sequences:

>Translated_683_residues
MVGDGIAKFIPEGFDAQKIPSFAIEKEPREQGALPADWVLVPEFSLTDGKANASLTVPEGTSIYGGGEVTGSLLRNGKTI
KLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGILFDTTWKAELSSTDEKIELKSEGIPFRVFIIDRESPQAVIRGL
SELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFRLKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIR
GFHSAWMIDPGAKVDPNYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQGVDGVWND
VNEPQINDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGFLMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGD
NGSCWDHLKMSVPMSLTLGLSGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASR
IALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIPAFANQPALPKGIWKELSLVEGD
QNDKYQAKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCLDEQGKASGNMYWDAGDGWSYKKGDYSLLQFVAERNGDKVT
VKLTKKTGKYNTENKDMAVIKIITDQGIRQASGNLVEGIEIRL
>Mature_683_residues
MVGDGIAKFIPEGFDAQKIPSFAIEKEPREQGALPADWVLVPEFSLTDGKANASLTVPEGTSIYGGGEVTGSLLRNGKTI
KLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGILFDTTWKAELSSTDEKIELKSEGIPFRVFIIDRESPQAVIRGL
SELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFRLKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIR
GFHSAWMIDPGAKVDPNYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQGVDGVWND
VNEPQINDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGFLMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGD
NGSCWDHLKMSVPMSLTLGLSGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASR
IALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIPAFANQPALPKGIWKELSLVEGD
QNDKYQAKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCLDEQGKASGNMYWDAGDGWSYKKGDYSLLQFVAERNGDKVT
VKLTKKTGKYNTENKDMAVIKIITDQGIRQASGNLVEGIEIRL

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=621, Percent_Identity=33.9774557165861, Blast_Score=343, Evalue=2e-94,
Organism=Homo sapiens, GI38202257, Length=621, Percent_Identity=33.9774557165861, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI66346737, Length=631, Percent_Identity=32.9635499207607, Blast_Score=333, Evalue=4e-91,
Organism=Homo sapiens, GI119393895, Length=612, Percent_Identity=32.1895424836601, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI119393893, Length=612, Percent_Identity=32.1895424836601, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI119393891, Length=612, Percent_Identity=32.1895424836601, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI221316699, Length=658, Percent_Identity=30.0911854103343, Blast_Score=269, Evalue=7e-72,
Organism=Homo sapiens, GI157364974, Length=621, Percent_Identity=30.1127214170692, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI310115361, Length=629, Percent_Identity=27.9809220985692, Blast_Score=231, Evalue=1e-60,
Organism=Escherichia coli, GI2367256, Length=506, Percent_Identity=26.4822134387352, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI2367323, Length=522, Percent_Identity=21.6475095785441, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71991189, Length=684, Percent_Identity=33.3333333333333, Blast_Score=347, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI17560798, Length=653, Percent_Identity=32.312404287902, Blast_Score=344, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI17560800, Length=653, Percent_Identity=32.312404287902, Blast_Score=344, Evalue=9e-95,
Organism=Caenorhabditis elegans, GI71985706, Length=649, Percent_Identity=28.1972265023112, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI32563849, Length=697, Percent_Identity=25.3945480631277, Blast_Score=171, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319706, Length=659, Percent_Identity=30.804248861912, Blast_Score=291, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24643749, Length=625, Percent_Identity=32.64, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24643753, Length=625, Percent_Identity=32.64, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24643751, Length=625, Percent_Identity=32.64, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24643746, Length=625, Percent_Identity=32.64, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI21357605, Length=625, Percent_Identity=32.64, Blast_Score=329, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 76154; Mature: 76154

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGDGIAKFIPEGFDAQKIPSFAIEKEPREQGALPADWVLVPEFSLTDGKANASLTVPEG
CCCCCHHHHCCCCCCHHCCCCCCCCCCHHHCCCCCCCEEEECCEECCCCCCCCEEECCCC
TSIYGGGEVTGSLLRNGKTIKLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGILFD
CEEECCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCEEEEEECCCCEEEEEEE
TTWKAELSSTDEKIELKSEGIPFRVFIIDRESPQAVIRGLSELTGTMPMIPRWALGYQQC
CCCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHCCHHHE
RFSYSPDSRVIEIADTFRLKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIR
EECCCCCCCEEEEECCEEEECCCCEEEEEEEEECCCEEEEEECCCCCCCHHHCCCCEEEE
GFHSAWMIDPGAKVDPNYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNK
EECCEEEECCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
WWRNLYKDFLAQGVDGVWNDVNEPQINDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGF
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECEEEE
LMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGDNGSCWDHLKMSVPMSLTLGL
EEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCEEEEECC
SGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASR
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCEEECCCCCHHHH
IALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIPAF
HHHHCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEECCCEEEECCCEEEEEEC
ANQPALPKGIWKELSLVEGDQNDKYQAKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCL
CCCCCCCHHHHHHHHEEECCCCCCEEEEEEECCCEECCCCHHHHCCCCCCCCCEEEEEEE
DEQGKASGNMYWDAGDGWSYKKGDYSLLQFVAERNGDKVTVKLTKKTGKYNTENKDMAVI
CCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEE
KIITDQGIRQASGNLVEGIEIRL
EEEECCCCHHHCCCEECCEEEEC
>Mature Secondary Structure
MVGDGIAKFIPEGFDAQKIPSFAIEKEPREQGALPADWVLVPEFSLTDGKANASLTVPEG
CCCCCHHHHCCCCCCHHCCCCCCCCCCHHHCCCCCCCEEEECCEECCCCCCCCEEECCCC
TSIYGGGEVTGSLLRNGKTIKLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGILFD
CEEECCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCEEEEEECCCCEEEEEEE
TTWKAELSSTDEKIELKSEGIPFRVFIIDRESPQAVIRGLSELTGTMPMIPRWALGYQQC
CCCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHCCHHHE
RFSYSPDSRVIEIADTFRLKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIR
EECCCCCCCEEEEECCEEEECCCCEEEEEEEEECCCEEEEEECCCCCCCHHHCCCCEEEE
GFHSAWMIDPGAKVDPNYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNK
EECCEEEECCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
WWRNLYKDFLAQGVDGVWNDVNEPQINDTPNKTMPEDNLHRGGGKLPAGTHLQYHNVYGF
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECEEEE
LMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGDNGSCWDHLKMSVPMSLTLGL
EEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCEEEEECC
SGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKVEDASR
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCEEECCCCCHHHH
IALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLLIIPAF
HHHHCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEECCCEEEECCCEEEEEEC
ANQPALPKGIWKELSLVEGDQNDKYQAKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCL
CCCCCCCHHHHHHHHEEECCCCCCEEEEEEECCCEECCCCHHHHCCCCCCCCCEEEEEEE
DEQGKASGNMYWDAGDGWSYKKGDYSLLQFVAERNGDKVTVKLTKKTGKYNTENKDMAVI
CCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEE
KIITDQGIRQASGNLVEGIEIRL
EEEECCCCHHHCCCEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]