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The map label for this gene is nadA [H]

Identifier: 29348573

GI number: 29348573

Start: 4034454

End: 4035392

Strand: Reverse

Name: nadA [H]

Synonym: BT_3164

Alternate gene names: 29348573

Gene position: 4035392-4034454 (Counterclockwise)

Preceding gene: 29348575

Following gene: 29348569

Centisome position: 64.46

GC content: 49.84

Gene sequence:

>939_bases
ATGAATAATCTCATAAAGGCTATTAATGAGCTGAAGAAAGAAAAGAATGCAATCATTCTGGGGCACTACTACCAGAAGGG
TGAAATACAAGATATCGCCGATTACGTTGGCGACAGTCTGGCGTTGGCTCAACTGGCTGCCAAAACGGAGGCGGACATCA
TTGTGATGTGCGGCGTTCACTTTATGGGTGAGACAGCGAAGGTGCTTTGTCCGGATAAGAAAGTGCTGGTGCCCGACATG
GAAGCGGGTTGTTCGCTGGCGGACAGTTGTCCGGCGGATCAGTTTGCGCAGTTTGTCAAAGAGCATCCGGGGCACACCGT
TATTTCGTACGTGAACACGACAGCTGCCGTGAAGGCGGTAACGGATGTGGTGGTGACTTCCACTAATGCCCGGCAGATCG
TGGAAAGTTTTCCCAAAGATGAGAAAATAATCTTTGGTCCGGACCGGAATCTGGGAAATTATATCAACTCAGTTACGAAC
AGGAATATGCTGCTTTGGGACGGAGCCTGTCATGTGCACGAACAGTTCTCGGTGGAAAAGATCGTGGAATTGAAAACGCA
GCATCCGGAAGCATTGGTGCTGGCACATCCCGAATGCAAAAGTACGGTGCTGAAACTGGCAGATGTGGTAGGGTCTACAG
CTGCACTGCTGAAGTATGCGGTGAACCACCCGGAGAATACGTATATCGTGGCTACCGAATCGGGTATCTTGCATGAGATG
CAGAAGAAGTGTCCGCAGACAACGTTTATCCCCGCTCCTCCGAACGATAGCACCTGTGGATGTAACGAGTGTAGCTTTAT
GCGGTTGAATACGTTAGAGAAGCTCTATGAGTGTCTGAAGAATGAGTCACCGGAGATTACTGTAGATCCCGAAATAGCGG
AGAAGGCAGTGAGGCCTATTCAGCGGATGCTGGAGATTTCGGCGAAGCTGGGATTATGA

Upstream 100 bases:

>100_bases
ATCCGGCAAGAAAAATCGTATTTATTTGCTAACACTATTAACAGGCTATCATCACTAACAAAGGATTTTTTTTAAAAGGA
AGAAATAAAAGAATATTATT

Downstream 100 bases:

>100_bases
TAGGATATACAAACGGTACCTTCCAATACATTAAACGGTACCATCCAACATACTGGATGGTACCGTTTAATGTATTGGAG
TGTACCATTCCGTGTATCAG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNNLIKAINELKKEKNAIILGHYYQKGEIQDIADYVGDSLALAQLAAKTEADIIVMCGVHFMGETAKVLCPDKKVLVPDM
EAGCSLADSCPADQFAQFVKEHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPKDEKIIFGPDRNLGNYINSVTN
RNMLLWDGACHVHEQFSVEKIVELKTQHPEALVLAHPECKSTVLKLADVVGSTAALLKYAVNHPENTYIVATESGILHEM
QKKCPQTTFIPAPPNDSTCGCNECSFMRLNTLEKLYECLKNESPEITVDPEIAEKAVRPIQRMLEISAKLGL

Sequences:

>Translated_312_residues
MNNLIKAINELKKEKNAIILGHYYQKGEIQDIADYVGDSLALAQLAAKTEADIIVMCGVHFMGETAKVLCPDKKVLVPDM
EAGCSLADSCPADQFAQFVKEHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPKDEKIIFGPDRNLGNYINSVTN
RNMLLWDGACHVHEQFSVEKIVELKTQHPEALVLAHPECKSTVLKLADVVGSTAALLKYAVNHPENTYIVATESGILHEM
QKKCPQTTFIPAPPNDSTCGCNECSFMRLNTLEKLYECLKNESPEITVDPEIAEKAVRPIQRMLEISAKLGL
>Mature_312_residues
MNNLIKAINELKKEKNAIILGHYYQKGEIQDIADYVGDSLALAQLAAKTEADIIVMCGVHFMGETAKVLCPDKKVLVPDM
EAGCSLADSCPADQFAQFVKEHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPKDEKIIFGPDRNLGNYINSVTN
RNMLLWDGACHVHEQFSVEKIVELKTQHPEALVLAHPECKSTVLKLADVVGSTAALLKYAVNHPENTYIVATESGILHEM
QKKCPQTTFIPAPPNDSTCGCNECSFMRLNTLEKLYECLKNESPEITVDPEIAEKAVRPIQRMLEISAKLGL

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=313, Percent_Identity=40.5750798722045, Blast_Score=250, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34309; Mature: 34309

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLIKAINELKKEKNAIILGHYYQKGEIQDIADYVGDSLALAQLAAKTEADIIVMCGVH
CCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCH
FMGETAKVLCPDKKVLVPDMEAGCSLADSCPADQFAQFVKEHPGHTVISYVNTTAAVKAV
HHCCCCEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
TDVVVTSTNARQIVESFPKDEKIIFGPDRNLGNYINSVTNRNMLLWDGACHVHEQFSVEK
HHHHEECCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHH
IVELKTQHPEALVLAHPECKSTVLKLADVVGSTAALLKYAVNHPENTYIVATESGILHEM
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHH
QKKCPQTTFIPAPPNDSTCGCNECSFMRLNTLEKLYECLKNESPEITVDPEIAEKAVRPI
HHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHH
QRMLEISAKLGL
HHHHHHHHHCCC
>Mature Secondary Structure
MNNLIKAINELKKEKNAIILGHYYQKGEIQDIADYVGDSLALAQLAAKTEADIIVMCGVH
CCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCH
FMGETAKVLCPDKKVLVPDMEAGCSLADSCPADQFAQFVKEHPGHTVISYVNTTAAVKAV
HHCCCCEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
TDVVVTSTNARQIVESFPKDEKIIFGPDRNLGNYINSVTNRNMLLWDGACHVHEQFSVEK
HHHHEECCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHH
IVELKTQHPEALVLAHPECKSTVLKLADVVGSTAALLKYAVNHPENTYIVATESGILHEM
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHH
QKKCPQTTFIPAPPNDSTCGCNECSFMRLNTLEKLYECLKNESPEITVDPEIAEKAVRPI
HHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHH
QRMLEISAKLGL
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]